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991.
通过三维动力学有限元法,以空间杆单元模拟缝线的增强作用,建立了缝合复合材料层板在横向低速冲击载荷作用下的渐近损伤分析模型。该模型考虑了缝合层板受低速冲击时的纤维断裂、基体开裂及分层等五种典型损伤形式,采用基于应变描述的Hashin失效准则和Yeh分层失效准则,并将其嵌入ABAQUS/Explicit用户子程序以实现相应损伤类型的判断及其材料性能退化。针对相同铺层的缝合与未缝合层板,模拟了低速冲击作用下的冲击响应和渐进损伤过程,数值结果与试验吻合较好,证明了该方法的合理有效性。同时探讨了冲击速度、缝合密度等对缝合层板冲击响应和损伤的影响。结果表明:有、无缝合层板的低速冲击响应具有类似的变化规律,缝合能够有效减小冲击损伤面积。随着缝合密度和缝线强度的增大,缝合对冲击损伤的抑制作用更为明显。  相似文献   
992.
MicroRNA(miRNA)是一种内源性的非编码单链RNA,通过与mRNA的3'端非翻译区(UTR)的不完全互补或完全互补结合抑制靶mRNA的翻译或促使靶mRNA的降解来调控基因的表达,参与细胞的增殖、凋亡、分化和代谢等重要过程。MiRNA表达的变化可以起到癌基因和抑癌基因的作用,是一种潜在的肿瘤标志物,因此,miRNA的检测技术引起了人们的关注。由于电化学检测方法具有灵敏、快速、低成本和低能耗等特点,研究者广泛开展了应用电化学技术来发展miRNA检测的研究。本文将对基于电化学技术的miRNA检测方法进行综述。  相似文献   
993.
In this paper,the singular value decomposition(SVD) method as a filter is applied before the tomographic inversion of soft-X-ray emission.Series of ’filtered’ signals including specific chronos and topos are obtained.(Here,chronos and topos are the decomposed spatial vectors and the decomposed temporal vectors,respectively).Given specific magnetic flux function with coupling m = 1 and m = 2 modes,the line-integrated soft-X-ray signals at all chords have been obtained.Then m = 1 and m = 2 modes have been identified by tomography of simulated ’filtered’ signals extracted by the SVD method.Finaly,using the experimental line-integrated soft-X-ray signals,m = 2 competent mode of complex magnetohydrodynamics(MHD) activities during internal soft disruption is observed.This result demonstrates that m = 2 mode plays an important role in internal disruption(Here,m is the poloidal mode number).  相似文献   
994.
采用G3B3//B3LYP/6-311++G(d,p)方法研究了HNCX (X=O, S)与F原子的反应机理. 找到了六条可能的反应通道, 计算结果表明, 该反应的主产物为HF+NCX (X=O, S). 对反应过程进行了电子密度拓扑分析, 讨论了反应过程中化学键的断裂和生成规律, 找到了HNCX (X=O, S)和F反应过程中的T型结构过渡态、三元环状结构过渡区和四元环状结构过渡区.  相似文献   
995.
In this work, ZnO nanorod/Cu2O composite nanostructure solar cells were prepared using hydrothermal growth and electrodeposition. The CdS layer was added between ZnO and Cu2O to suppress carrier reverse recombination. Nondestructive interface deposition methods were employed to prepare CdS and Cu2O functional layers. The CdS layers were unconventionally deposited in non-alkaline solution, which can inhibit etching on the ZnO surface, and Cu2O layers were electrodeposited in ZnO-buffered alkaline solution which can also inhibit etching on the ZnO surface. Finally, the performance of solar cells was improved by adding a highly resistive CdS intermediate layer between ZnO and Cu2O layers. This work demonstrated the nondestructive interface approach of chemical solution deposition of functional layers on ZnO and possibilities for further improvements to the performance of Cu2O-based nanostructure solar cells with the addition of an intermediated layer.  相似文献   
996.
A \(\gamma \)-ray spectroscopy system based on a 1\(^{\prime \prime }\times 1^{\prime \prime }\) NaI(Tl) detector and 1.5\(^{\prime \prime }\) photomultiplier tube has been developed at IUAC for teaching laboratory applications involving radioactive sources. Following along the lines of the Phoenix and Expeyes hardware developed in the laboratory earlier, a low-cost, light weight multichannel analyser also has been developed. Here the details about the same are presented. The detector–analyser system has been used as a part of the postgraduate curriculum for measuring \(^{40}\)K content in some potassium salts and common building materials like brick, cement, concrete and sand.  相似文献   
997.
黄浩  张侃  吴明  李虎  王敏涓  张书铭  陈建宏  文懋 《物理学报》2018,67(19):197203-197203
准确测量和分析SiC纤维增强Ti合金复合材料(SiC_f/Ti)中残余应力状态对优化复合材料的成型工艺和理解其失效模式具有重要意义,但其残余应力的实验测量和分析仍是一个挑战.石墨C涂层作为SiC纤维与Ti17基体合金之间必需的扩散障涂层,承载了由纤维与基体之间热不匹配引入的残余应力.本文采用显微拉曼光谱法对比测量纤维表面C涂层在复合材料中和去掉基体无应力态下G峰的峰位,通过石墨C涂层应力态下峰位移动计算出SiCf/C/Ti17复合材料中SiC纤维受到~705.0 MPa的残余压应力.采用X射线衍射方法测量了不同方向上该复合材料中基体钛合金的晶面间距以获取其空间应变,根据三轴应力模型分析了复合材料中基体钛合金沿轴向方向的残余应力为~701.3 MPa的张应力,并通过线性弹性理论转化为SiC纤维的残余压应力为~759.4 MPa.两种测试方法都确定了SiC纤维在成型过程中受到残余压应力,且获得的应力值较为接近,都可以用于对SiC_f/Ti复合材料的残余应力测量.  相似文献   
998.
Stimuli-activatable and subcellular organelle-targeted agents with multimodal therapeutics are urgently desired for highly precise and effective cancer treatment. Herein, a CO/light dual-activatable Ru(ii)-oligo-(thiophene ethynylene) (Ru-OTE) for lysosome-targeted cancer therapy is reported. Ru-OTE is prepared via the coordination-driven self-assembly of a cationic conjugated oligomer (OTE-BN) ligand and a Ru(ii) center. Upon the dual-triggering of internal gaseous signaling molecular CO and external light, Ru-OTE undergoes ligand substitution and releases OTE-BN followed by dramatic fluorescence recovery, which could be used for monitoring drug delivery and imaging guided anticancer treatments. The released OTE-BN selectively accumulates in lysosomes, physically breaking their integrity. Then, the generated cytotoxic singlet oxygen (1O2) causes severe lysosome damage, thus leading to cancer cell death via photodynamic therapy (PDT). Meanwhile, the release of the Ru(ii) core also suppresses cancer cell growth as an anticancer metal drug. Its significant anticancer effect is realized via the multimodal therapeutics of physical disruption/PDT/chemotherapy. Importantly, Ru-OTE can be directly photo-activated using a two-photon laser (800 nm) for efficient drug release and near-infrared PDT. Furthermore, Ru-OTE with light irradiation inhibits tumor growth in an MDA-MB-231 breast tumor model with negligible side effects. This study demonstrates that the development of an activatable Ru(ii)-conjugated oligomer potential drug provides a new strategy for effective subcellular organelle-targeted multimodal cancer therapeutics.

The anticancer therapeutics of lysosome disruption/PDT/chemotherapy based on Ru-OTE complex was achieved, which provides a new strategy for developing multimodal and effective stimuli-activatable subcellular organelle-targeted cancer therapeutics.  相似文献   
999.
We consider a group of agents playing the Hawk-Dove game. These agents have a finite memory of past interactions which they use to optimize their play. By both analytical and numerical approaches, we show that an instability occurs at a critical memory length, and we provide its characterization. We show also that when the game is stable, having a long memory is beneficial but that instability, which may be produced by excessively long memory, hands the advantage to those with shorter memories.  相似文献   
1000.
Implementing an arbitrated quantum signature(QAS) through complex networks is an interesting cryptography technology in the literature. In this paper, we propose an arbitrated quantum signature for the multi-user-involved networks, whose topological structures are established by the encoded graph state. The determinative transmission of the shared keys, is enabled by the appropriate stabilizers performed on the graph state. The implementation of this scheme depends on the deterministic distribution of the multi-user-shared graph state on which the encoded message can be processed in signing and verifying phases. There are four parties involved, the signatory Alice, the verifier Bob, the arbitrator Trent and Dealer who assists the legal participants in the signature generation and verification. The security is guaranteed by the entanglement of the encoded graph state which is cooperatively prepared by legal participants in complex quantum networks.  相似文献   
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