排序方式: 共有89条查询结果,搜索用时 31 毫秒
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We introduce a class of matrix-valued radial basis functions (RBFs) of compact support that can be customized, e.g. chosen to be divergence-free. We then derive and discuss error estimates for interpolants and derivatives based on these matrix-valued RBFs. 相似文献
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Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions 下载免费PDF全文
Dr. Svenja Morsbach Dr. Grazia Gonella Prof. Dr. Volker Mailänder Dr. Seraphine Wegner Dr. Si Wu Prof. Dr. Tobias Weidner Dr. Rüdiger Berger Dr. Kaloian Koynov Prof. Dr. Doris Vollmer Dr. Noemí Encinas Dr. Seah Ling Kuan Dr. Tristan Bereau Prof. Kurt Kremer Prof. Dr. Tanja Weil Prof. Dr. Mischa Bonn Prof. Dr. Hans‐Jürgen Butt Prof. Dr. Katharina Landfester 《Angewandte Chemie (International ed. in English)》2018,57(39):12626-12648
Once materials come into contact with a biological fluid containing proteins, proteins are generally—whether desired or not—attracted by the material's surface and adsorb onto it. The aim of this Review is to give an overview of the most commonly used characterization methods employed to gain a better understanding of the adsorption processes on either planar or curved surfaces. We continue to illustrate the benefit of combining different methods to different surface geometries of the material. The thus obtained insight ideally paves the way for engineering functional materials that interact with proteins in a predetermined manner. 相似文献
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Fleischer S Werkmeister S Zhou S Junge K Beller M 《Chemistry (Weinheim an der Bergstrasse, Germany)》2012,18(29):9005-9010
Enantiomerically pure chiral amines are of increasing importance and commercial value in the fine chemical, pharmaceutical, and agrochemical industries. Here, we describe the straightforward synthesis of chiral amines by combining the atom-economic and environmentally friendly hydroamination of alkynes with an enantioselective hydrogenation of in situ generated imines by using inexpensive hydrogen. By following this novel approach, a wide range of terminal alkynes can be reductively hydroaminated with primary amines including alkyl-, and arylalkynes as well as aryl and heteroaryl amines. Excellent yields and selectivities up to 94?%?ee and 96?% isolated yield were obtained. 相似文献
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Srividya Ganapathy Svenja Kratz Que Chen Klaas J. Hellingwerf Huub J.M. de Groot Kenneth J. Rothschild Willem J. de Grip 《Photochemistry and photobiology》2019,95(4):959-968
Archaerhodopsin‐3 (AR3) is a member of the microbial rhodopsin family of hepta‐helical transmembrane proteins, containing a covalently bound molecule of all‐trans retinal as a chromophore. It displays an absorbance band in the visible region of the solar spectrum (λmax 556 nm) and functions as a light‐driven proton pump in the archaeon Halorubrum sodomense. AR3 and its mutants are widely used in neuroscience as optogenetic neural silencers and in particular as fluorescent indicators of transmembrane potential. In this study, we investigated the effect of analogs of the native ligand all‐trans retinal A1 on the spectral properties and proton‐pumping activity of AR3 and its single mutant AR3 (F229S). While, surprisingly, the 3‐methoxyretinal A2 analog did not redshift the absorbance maximum of AR3, the analogs retinal A2 and 3‐methylamino‐16‐nor‐1,2,3,4‐didehydroretinal (MMAR) did generate active redshifted AR3 pigments. The MMAR analog pigments could even be activated by near‐infrared light. Furthermore, the MMAR pigments showed strongly enhanced fluorescence with an emission band in the near‐infrared peaking around 815 nm. We anticipate that the AR3 pigments generated in this study have widespread potential for near‐infrared exploitation as fluorescent voltage‐gated sensors in optogenetics and artificial leafs and as proton pumps in bioenergy‐based applications. 相似文献
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Dr. Manuel Hodecker Dr. Yury Kozhemyakin Svenja Weigold Dr. Frank Rominger Dr. Jan Freudenberg Prof. Dr. Andreas Dreuw Prof. Dr. Uwe H. F. Bunz 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(71):16990-16993
The synthesis of a doubly bridged 1,4-bis(phenylethynyl)benzene is reported. The target displays photophysical properties, distinctly different from that of its congeners, the singly bridged tolans. Quantum-chemical calculations suggest a lack of planarization of the bridged bis(phenylethynyl)benzene in the first excited state. 相似文献