Gamma peak search and peak fitting algorithm for a low-resolution detector with applications in gamma spectroscopy

A Savitzky–Golay filtering for smoothing and peak search written in Python is presented in this paper alongside its applications in the list-mode digital data acquisition dual gamma–gamma coincidence bismuth germanate (BGO) detector. The study has demonstrated that the software provides a reliable and effective way to quantify trace amounts of ²²Na and ⁷Be in aerosol samples collected at Resolute Bay, Canada with a critical limit of 3 mBq and 5 Bq respectively for a 20 h counting interval, which are believed to be the inherent limitations of the dual-BGO system.

     

不同杂环取代(E)-β-Farnesene类似物的合成及生物活性研究

为了寻求新型蚜虫控制剂,以蚜虫报警信息素(E)-β-farnesene(EBF)为先导,引入不同类型的杂环取代EBF结构中不稳定的共轭双键,设计合成了一系列不同杂环取代的EBF类似物.所有化合物结构均通过1H NMR、13C NMR、IR及HRMS确证.对化合物进行了生物活性测试及初步构效关系分析.结果表明,所有化合物均对桃蚜和大豆蚜表现出一定的生物活性,部分化合物的杀虫活性优于先导EBF,酯基的引入则对驱避活性有利.     

Preparation and gas sensing activity of La and Y co-doped titania nanoparticles

Journal of Sol-Gel Science and Technology - A novel gas sensing material, La–Y co-doped TiO2 nanoparticles, was synthesized by sol–gel method and applied to detect organic pollutants...     

A dynamic dissemination model for recurring online public opinion

Nonlinear Dynamics - With an increasing number of people sharing feelings and opinions online, the online platforms have become one of the most important channels for public opinion dissemination....     

Identification of the Enzymes Mediating the Maturation of the Seryl-tRNA Synthetase Inhibitor SB-217452 during the Biosynthesis of Albomycins

Albomycin δ₂ is a sulfur-containing sideromycin natural product that shows potent antibacterial activity against clinically important pathogens. The l -serine-thioheptose dipeptide partial structure, known as SB-217452, has been found to be the active seryl-tRNA synthetase inhibitor component of albomycin δ₂. Herein, it is demonstrated that AbmF catalyzes condensation between the 6′-amino-4′-thionucleoside with the d -ribo configuration and seryl-adenylate supplied by the serine adenylation activity of AbmK. Formation of the dipeptide is followed by C3′-epimerization to produce SB-217452 with the d -xylo configuration, which is catalyzed by the radical S-adenosyl-l -methionine enzyme AbmJ. Gene deletion suggests that AbmC is involved in peptide assembly linking SB-217452 with the siderophore moiety. This study establishes how the albomycin biosynthetic machinery generates its antimicrobial component SB-217452.