Simple and robust digital holography for high-resolution imaging

Based on the point spread function of holographic system,the lateral resolution of digital holographic imaging system without any pre-magnification is studied.The expression of resolution limitation of holographic imaging system is thus presented.We investigate the possibilities to improve the lateral resolution.The simple experimental setup with an off-axis arrangement is built.By using a U.S.Air Force(USAF)test target as microscopic object,the recorded holograms are reconstructed digitally based on the principle of Fresnel diffraction.The lateral resolution of 2.76 μm without any pre-magnification is demonstrated experimentally,which matches the theoretical prediction well.     

Oral fluid/plasma cannabinoid ratios following controlled oral THC and smoked cannabis administration

Oral fluid (OF) is a valuable biological alternative for clinical and forensic drug testing. Evaluating OF to plasma (OF/P) cannabinoid ratios provides important pharmacokinetic data on the disposition of drug and factors influencing partition between matrices. Eleven chronic cannabis smokers resided on a closed research unit for 51 days. There were four 5-day sessions of 0, 30, 60, and 120 mg oral ?⁹-tetrahydrocannabinol (THC)/day followed by a five-puff smoked cannabis challenge on Day 5. Each session was separated by 9 days ad libitum cannabis smoking. OF and plasma specimens were analyzed for THC and metabolites. During ad libitum smoking, OF/P THC ratios were high (median, 6.1; range, 0.2–348.5) within 1 h after last smoking, decreasing to 0.1–20.7 (median, 2.1) by 13.0–17.1 h. OF/P THC ratios also decreased during 5-days oral THC dosing, and after the smoked cannabis challenge, median OF/P THC ratios decreased from 1.4 to 5.5 (0.04–245.6) at 0.25 h to 0.12 to 0.17 (0.04–5.1) at 10.5 h post-smoking. In other studies, longer exposure to more potent cannabis smoke and oromucosal cannabis spray was associated with increased OF/P THC peak ratios. Median OF/P 11-nor-9-carboxy-THC (THCCOOH) ratios were 0.3–2.5 (range, 0.1–14.7) ng/μg, much more consistent in various dosing conditions over time. OF/P THC, but not THCCOOH, ratios were significantly influenced by oral cavity contamination after smoking or oromucosal spray of cannabinoid products, followed by time-dependent decreases. Establishing relationships between OF and plasma cannabinoid concentrations is essential for making inferences of impairment or other clinical outcomes from OF concentrations.     

Beam quality factor of mixed modes emerging from a multimode step-index fiber

The beam quality factors (or M² parameter) of coherent and incoherent superposition of the several lower-order LP modes emerging from a step-index fiber have been calculated by using the second-order moment method. The results indicate that, for an individual LP mode, the M² parameter takes its maximum value when the normalized frequency V of the step-index fiber approaches the cut-off frequency, and it gradually becomes constant as V increases. In the case of incoherent superposition, the larger the fraction intensity carried by the higher-order mode, the larger the beam quality factor M². Under certain circumstances, the value of the M² parameter of the mixed mode that comprises several LP-modes contents may become even smaller and closer to the ideal Gaussian beam than that of the fundamental mode in a step-index fiber. However, in the case of the coherent superposition, the value of the M² parameter of the mixed mode may be greater than that of the higher-order constituent mode. The results reported here could be helpful for the application of the high-power fiber laser systems.     

Scattering of simple harmonic waves by a circular cavity in a fluid-infiltrated poro-elastic medium

Scattering by a cylindrical cavity in a porous solid is studied by the boundary layer approximation of Mei and Foda. Quantitative results will be presented for two cases: (1) vacuum cavity and (2) cavity filled with fluid. In each case both P and SV incident waves will be studied. Focus will be on the stress distribution near the cavity surface and contrast to the non-porous case will be pointed out. The effect of fluid compressibility due to possible entrainment of air will be discussed. These results should be of interest to the design of long tunnels subject to earthquakes.     

Mathematical method to predict the diffraction efficiency of holograms

In this paper, a method is presented which uses a multi-factorial decision model of fuzzy-set theory to predict the diffraction efficiency of holograms. A prediction fitting rate of 85% has been obtained. This method can be used as a guide to processing holograms.     

O2-2,4-二硝基苯基偶氮二醇盐类化合物的设计、合成及抗肿瘤活性

以O2-2,4-二硝基苯基偶氮二醇盐(PABA/NO)为先导化合物,选择适当的仲胺作为偶氮二醇盐中相应的胺片段,并用碳氮键取代苯环5位的碳氧酯键,设计合成了化合物2a,2b和4a~4j,以期获得活性更强且稳定性好的抗肿瘤药物.目标化合物经1H NMR,13C NMR及HRMS进行了结构确证.生物活性测试结果表明,目标化合物可不同程度地抑制结肠癌HCT-116细胞的增殖,其中化合物4h的活性最强(IC50=7.945±0.421 μmol/L),优于PABA/NO(IC50=12.134±0.675 μmol/L).NO释放实验结果表明,此类化合物的NO释放量与细胞毒性呈正相关.化合物4h在HCT-116细胞中释放NO的量最多,约是正常细胞的2倍.此外,化合物4h在大鼠血浆中的体外稳定性显著优于PABA/NO,值得进一步研究.     

MSM结构Mg0.2Zn0.8O可见盲光电探测器

采用射频磁控溅射,通过传统的紫外曝光和湿法腐蚀的方法,制备了不同电极间距的金属-半导体-金属(MSM)结构Mg0.2Zn0.8O可见盲光电探测器.研究了器件的暗电流和响应度随电极间距的变化关系,当施加的电压没有达到贯穿电压的时候,暗电流和响应度均随着电极间距的增加而减小,并对其具体的机制进行了研究.     

模糊层次分析法及其在优化建材连锁配送方案中的应用

本文首先说明模糊ＡＨＰ方法是在传统的ＡＨＰ方法的基础上，考虑到人们对复杂事物判断的模糊性，提出程度分析和综合决策理论，并介绍了模糊ＡＨＰ方法的主要理论及步骤。最后把它用于建材连锁配送系统模式的评价，可将专家对诸方案指标体系所进行的带有模糊性判断，通过定量计算，转化为对连锁配送系统模式的排序，从而达到选优的目的。     

Distributed optical fiber surface plasmon resonance sensors

The relationships of the resonant wavelength of optical fiber surface plasmon resonance (SPR) sensors to the modulation layer refractive index, thickness and the refractive index of the bulk medium are obtained by using theoretical calculation model of optical fiber SPR sensors under certain conditions, which indicates that resonant wavelength of the sensors is approximately linear with modulation layer thickness. Based on the linear relationship, multiple SPR sensors with different resonant wavelengths can be fabricated in a single optical fiber named as distributed optical fiber surface plasmon resonance sensors (DOFSPRSs).Experimental results are presented, showing that it is practical to fabricate more than one SPR sensors in a single optical fiber.     

曲面钣金件伸长翻边数值与解析研究

采用弹塑性大变形有限元方法研究了几何形状和材料参数对"V"型零件翻边的影响; 同时基于全量塑性理论及膜应变假定,推导了轴对称情况(管形件翻边)的解析计算模型,通过与有限元结果的比较,分析了解析模型的适用性.