Local stationarity in small area estimation models

Small area estimators are often based on linear mixed models under the assumption that relationships among variables are stationary across the area of interest (Fay–Herriot models). This hypothesis is patently violated when the population is divided into heterogeneous latent subgroups. In this paper we propose a local Fay–Herriot model assisted by a Simulated Annealing algorithm to identify the latent subgroups of small areas. The value minimized through the Simulated Annealing algorithm is the sum of the estimated mean squared error (MSE) of the small area estimates. The technique is employed for small area estimates of erosion on agricultural land within the Rathbun Lake Watershed (IA, USA). The results are promising and show that introducing local stationarity in a small area model may lead to useful improvements in the performance of the estimators.     

Alternative estimator for the parameters of a mixture of two binomial distributions

The method of moments has been widely used as a simple alternative to the maximum likelihood method, mainly because of its efficiency and simplicity in obtaining parameter estimators of a mixture of two binomial distributions. In this paper, an alternative estimate is proposed which is as competitive as of the method of moments when comparing the mean squared error and computational effort.     

On-Line Process Control using Attributes with Misclassification Errors: An Economical Design for Short-Run Production

On-line process control consists of inspecting a single item for every m (integer and m ≥ 2) produced items. Based on the results of the inspection, it is decided whether the process is in-control (the fraction of conforming items is p ₁; State I) or out-of-control (the fraction of conforming items is p ₂ < p ₁; State II). If the inspected item is non conforming, it is determined that the process is out-of-control, and the production process is stopped for an adjustment; otherwise, production continues. As most designs of on-line process control assume a long-run production, this study can be viewed as an extension because it is concerned with short-run production and the decision regarding the process is subject to misclassification errors. The probabilistic model of the control system employs properties of an ergodic Markov chain to obtain the expression of the average cost of the system per unit produced, which can be minimised as a function of the sampling interval, m. The procedure is illustrated by a numerical example.     

Estimates based on preliminary data from a specific subsample and from respondents not included in the subsample

Various approaches to obtaining estimates based on preliminary data are outlined. A case is then considered which frequently arises when selecting a subsample of units, the information for which is collected within a deadline that allows preliminary estimates to be produced. At the moment when these estimates have to be produced it often occurs that, although the collection of data on subsample units is still not complete, information is available on a set of units which does not belong to the sample selected for the production of the preliminary estimates. An estimation method is proposed which allows all the data available on a given date to be used to the full-and the expression of the expectation and variance are derived. The proposal is based on two-phase sampling theory and on the hypothesis that the response mechanism is the result of random processes whose parameters can be suitably estimated. An empirical analysis of the performance of the estimator on the Italian Survey on building permits concludes the work. The Sects. 1,2,3,4 and the technical appendixes have been developed by Giorgio Alleva and Piero Demetrio Falorsi; Sect. 5 has been done by Fabio Bacchini and Roberto Iannaccone. Piero Demetrio Falorsi is chief statisticians at Italian National Institute of Statistics (ISTAT); Giorgio Alleva is Professor of Statistics at University “La Sapienza” of Rome, Fabio Bacchini and Roberto Iannaccone are researchers at ISTAT.     

A sequential approach to testing seasonal unit roots in high frequency data

In this paper we introduce a sequential seasonal unit root testing approach which explicitly addresses its application to high frequency data. The main idea is to see which unit roots at higher frequency data can also be found in temporally aggregated data. We illustrate our procedure to the analysis of monthly data, and we find, upon analysing the aggregated quarterly data, that a smaller amount of test statistics can sometimes be considered. Monte Carlo simulation and empirical illustrations emphasize the practical relevance of our method.     

Older women's experiences with chronic pain: daily challenges and self-care practices

The subjective nature of chronic pain leads to challenges in describing, treating, and accommodating pain. Twenty older women, who engaged in focus groups, and eight of whom also participated in individual interviews, discussed the influence of chronic pain on their perception of self as well as daily functioning. Managing pain forced many of the women to withdraw from social activities that they valued and interfered with sleep patterns, household tasks and recreational activities. Varied acceptance by social network members added to the challenge of adjusting to complications associated with pain. Self-care practices that supported independence contributed to women's perceived success in daily functioning.     

Statistical methods for handling missing data to align with treatment policy strategy

The International Council for Harmonization (ICH) E9(R1) addendum recommends choosing an appropriate estimand based on the study objectives in advance of trial design. One defining attribute of an estimand is the intercurrent event, specifically what is considered an intercurrent event and how it should be handled. The primary objective of a clinical study is usually to assess a product's effectiveness and safety based on the planned treatment regimen instead of the actual treatment received. The estimand using the treatment policy strategy, which collects and analyzes data regardless of the occurrence of intercurrent events, is usually utilized. In this article, we explain how missing data can be handled using the treatment policy strategy from the authors' viewpoint in connection with antihyperglycemic product development programs. The article discusses five statistical methods to impute missing data occurring after intercurrent events. All five methods are applied within the framework of the treatment policy strategy. The article compares the five methods via Markov Chain Monte Carlo simulations and showcases how three of these five methods have been applied to estimate the treatment effects published in the labels for three antihyperglycemic agents currently on the market.