全文获取类型
收费全文 | 497篇 |
免费 | 31篇 |
国内免费 | 2篇 |
学科分类
医药卫生 | 530篇 |
出版年
2023年 | 3篇 |
2022年 | 8篇 |
2021年 | 11篇 |
2020年 | 10篇 |
2019年 | 10篇 |
2018年 | 18篇 |
2017年 | 7篇 |
2016年 | 18篇 |
2015年 | 25篇 |
2014年 | 25篇 |
2013年 | 21篇 |
2012年 | 36篇 |
2011年 | 42篇 |
2010年 | 25篇 |
2009年 | 14篇 |
2008年 | 27篇 |
2007年 | 27篇 |
2006年 | 40篇 |
2005年 | 22篇 |
2004年 | 23篇 |
2003年 | 23篇 |
2002年 | 20篇 |
2001年 | 3篇 |
2000年 | 10篇 |
1999年 | 12篇 |
1998年 | 4篇 |
1997年 | 6篇 |
1996年 | 3篇 |
1995年 | 1篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1991年 | 1篇 |
1988年 | 2篇 |
1987年 | 4篇 |
1984年 | 1篇 |
1983年 | 3篇 |
1982年 | 4篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1978年 | 1篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1975年 | 3篇 |
1974年 | 2篇 |
1973年 | 5篇 |
排序方式: 共有530条查询结果,搜索用时 15 毫秒
81.
B Girolami E Bernardi M H Prins J W ten Cate P Prandoni P Simioni G M Andreozzi A Girolami H R Büller 《European journal of vascular and endovascular surgery》2000,19(4):370-380
OBJECTIVES: To evaluate the efficacy of conservative adjuvant therapy after revascularisation procedures in patients with peripheral arterial disease. DESIGN: meta-analysis. MATERIALS: English-language studies published from 1976 to 1997. METHODS: Reports on conservative therapies in patients with peripheral arterial disease after percutaneous transluminal angioplasty, endarterectomy, thromboendarterectomy or bypass grafting were eligible. Uncontrolled or retrospective studies, double reports or trials without clinical outcomes were excluded. Included studies were graded as level 1 (randomised and double- or assessor-blind), level 2 (open randomised), or level 3 (non-randomised comparative). (Loss of) patency, amputation, vascular events and mortality were the outcomes considered. When feasible, end-of-treatment results, either continuous or binary, were combined with appropriate statistical methods. RESULTS: Thirty-two studies were included. Compared to non-active control, aspirin with dipyridamole improved (loss of) patency (odds ratio (OR) 0.69, 95% confidence interval (CI), 0.53 to 0.90) and mortality (OR 0.80, 95% CI, 0.57 to 1.14); ticlopidine improved (loss of) patency (OR 0.53, 95% CI, 0.33 to 0.85) and amputation (OR 0.29, 95% CI, 0.08 to 1.01). Data on the effectiveness of vitamin-K inhibitors were not conclusive. CONCLUSIONS: Patients with peripheral arterial disease improve their outcome by receiving aspirin with dipyridamole or ticlopidine after a revascularisation procedure. 相似文献
82.
Elisabetta Manaresi Giorgio Gallinella Marialuisa Zerbini Simona Venturoli Giovanna Gentilomi Monica Musiani 《Journal of medical virology》1999,57(2):174-178
Human B19 parvovirus recombinant capsid proteins VP1 and VP2 were expressed in E. coli and purified. Recombinant proteins were used to detect a specific IgG immune response against VP1 and VP2 linear epitopes by immunoblot assay. A total of 222 serum samples from 218 apparently immunocompetent subjects with different clinical conditions and laboratory evaluations with regards to B19 infection were analyzed. The sera had previously been tested for B19 DNA and for specific IgM and IgG against VP2 conformational antigens by ELISA assay. The data show that, during the active or very recent phase of infection, IgG anti-VP1 linear epitopes appear in concomitance and with the same frequency as IgG anti-VP2 conformational antigens. IgG against conformational VP2 antigens and against linear VP1 epitopes seem to persist for months or years in the majority of individuals. IgG against VP2 linear epitopes are generally present during the active or very recent phase of infection and during the convalescent phase, while they are present only in about 20% of subjects with signs of a past B19 infection. J. Med. Virol. 57:174–178, 1999. © 1999 Wiley-Liss, Inc. 相似文献
83.
84.
Marialuisa Quadri Wim Mandemakers Martyna M Grochowska Roy Masius Hanneke Geut Edito Fabrizio Guido J Breedveld Demy Kuipers Michelle Minneboo Leonie J M Vergouw Ana Carreras Mascaro Ekaterina Yonova-Doing Erik Simons Tianna Zhao Alessio B Di Fonzo Hsiu-Chen Chang Piero Parchi Marta Melis Vincenzo Bonifati 《Lancet neurology》2018,17(7):597-608
85.
Valantis Fyndanis Giorgio Arcara Rita Capasso Paraskevi Christidou Serena De Pellegrin Marialuisa Gandolfi 《Clinical linguistics & phonetics》2018,32(9):823-843
Recent studies by Bastiaanse and colleagues found that time reference is selectively impaired in people with nonfluent agrammatic aphasia, with reference to the past being more difficult to process than reference to the present or to the future. To account for this dissociation, they formulated the PAst DIscourse LInking Hypothesis (PADILIH), which posits that past reference is more demanding than present/future reference because it involves discourse linking. There is some evidence that this hypothesis can be applied to people with fluent aphasia as well. However, the existing evidence for the PADILIH is contradictory, and most of it has been provided by employing a test that predominantly taps retrieval processes, leaving largely unexplored the underlying ability to encode time reference-related prephonological features. Within a cross-linguistic approach, this study tests the PADILIH by means of a sentence completion task that 'equally' taps encoding and retrieval abilities. This study also investigates if the PADILIH’s scope can be extended to fluent aphasia. Greek- and Italian-speaking individuals with aphasia participated in the study. The Greek group consisted of both individuals with nonfluent agrammatic aphasia and individuals with fluent aphasia, who also presented signs of agrammatism. The Italian group consisted of individuals with agrammatic nonfluent aphasia only. The two Greek subgroups performed similarly. Neither language group of participants with aphasia exhibited a pattern of performance consistent with the predictions of the PADILIH. However, a double dissociation observed within the Greek group suggests a hypothesis that may reconcile the present results with the PADILIH. 相似文献
86.
Fabrizio Zeri Paolo Calcatelli Eleonora Funaro Marialuisa Martelli Shehzad A. Naroo 《International ophthalmology》2018,38(4):1473-1484
Purpose
To evaluate the accuracy and repeatability of a computer-generated Pelli–Robson test displayed on liquid crystal display (LCD) systems compared to a standard Pelli–Robson chart.Methods
Two different randomized crossover experiments were carried out for two different LCD systems for 32 subjects: 6 females and 10 males (40.5 ± 13.0 years) and 9 females and 7 males (27.8 ± 12.2 years), respectively, in the first and second experiment. Two repeated measurements were taken with the printed Pelli–Robson test and with the LCDs at 1 and 3 m. To test LCD reliability, measurements were repeated after 1 week.Results
In Experiment 1, contrast sensitivity (CS) measured with LCD1 resulted significantly higher than Pelli–Robson both at 1 and at 3 m of about 0.20 log 1/C in both eyes (p < 0.01). Bland–Altman plots showed a proportional bias for LCD1 measures. LCD1 measurements showed reasonable repeatability: ICC was 0.83 and 0.65 at 1 and 3 m, respectively. In Experiment 2, CS measured with LCD2 resulted significantly lower than Pelli–Robson both at 1 and at 3 m of about 0.10 log 1/C in both eyes (p < 0.01). Bland–Altman plots did not show any proportional bias for LCD2 measures. LCD2 measurements showed sufficient repeatability: ICC resulted 0.51 and 0.65 at 1 and 3 m, respectively.Conclusions
Computer-generated versions of Pelli–Robson test, displayed on LCD systems, do not provide accurate results compared to classic Pelli–Robson printed version. Clinicians should consider that Pelli–Robson computer-generated versions could be non-interchangeable to the printed version.87.
88.
Picelli Alessandro Bonazza Sara Lobba Davide Parolini Massimo Martini Alvise Chemello Elena Gandolfi Marialuisa Polati Enrico Smania Nicola Schweiger Vittorio 《Neurological sciences》2017,38(9):1697-1701
Neurological Sciences - Hemiplegic shoulder pain is the most common pain condition after stroke. Suprascapular nerve block is an effective treatment for shoulder pain. The aim of this pilot study... 相似文献
89.
Toste A Soares R Feliciano J Andreozzi V Silva S Abreu A Ramos R Santos N Ferreira L Ferreira RC 《Revista portuguesa de cardiologia》2011,30(10):781-787
IntroductionA growing body of evidence shows the prognostic value of oxygen uptake efficiency slope (OUES), a cardiopulmonary exercise test (CPET) parameter derived from the logarithmic relationship between O2 consumption (VO2) and minute ventilation (VE) in patients with chronic heart failure (CHF).ObjectiveTo evaluate the prognostic value of a new CPET parameter — peak oxygen uptake efficiency (POUE) — and to compare it with OUES in patients with CHF.MethodsWe prospectively studied 206 consecutive patients with stable CHF due to dilated cardiomyopathy — 153 male, aged 53.3 ± 13.0 years, 35.4% of ischemic etiology, left ventricular ejection fraction 27.7 ± 8.0%, 81.1% in sinus rhythm, 97.1% receiving ACE-Is or ARBs, 78.2% beta-blockers and 60.2% spironolactone — who performed a first maximal symptom-limited treadmill CPET, using the modified Bruce protocol. In 33% of patients an cardioverterdefibrillator (ICD) or cardiac resynchronization therapy device (CRT-D) was implanted during follow-up.Peak VO2, percentage of predicted peak VO2, VE/VCO2 slope, OUES and POUE were analyzed. OUES was calculated using the formula VO2 (l/min) = OUES (log10VE) + b. POUE was calculated as pVO2 (l/min) / log10peakVE (l/min). Correlation coefficients between the studied parameters were obtained. The prognosis of each variable adjusted for age was evaluated through Cox proportional hazard models and R2 percent (R2%) and V index (V6) were used as measures of the predictive accuracy of events of each of these variables. Receiver operating characteristic (ROC) curves from logistic regression models were used to determine the cut-offs for OUES and POUE.ResultspVO2: 20.5 ± 5.9; percentage of predicted peak VO2: 68.6 ± 18.2; VE/VCO2 slope: 30.6 ± 8.3; OUES: 1.85 ± 0.61; POUE: 0.88 ± 0.27. During a mean follow-up of 33.1 ± 14.8 months, 45 (21.8%) patients died, 10 (4.9%) underwent urgent heart transplantation and in three patients (1.5%) a left ventricular assist device was implanted. All variables proved to be independent predictors of this combined event; however, VE/VCO2 slope was most strongly associated with events (HR 11.14). In this population, POUE was associated with a higher risk of events than OUES (HR 9.61 vs. 7.01), and was also a better predictor of events (R2: 28.91 vs. 22.37).ConclusionPOUE was more strongly associated with death, urgent heart transplantation and implantation of a left ventricular assist device and proved to be a better predictor of events than OUES. These results suggest that this new parameter can increase the prognostic value of CPET in patients with CHF. 相似文献
90.