全文获取类型
收费全文 | 838篇 |
免费 | 39篇 |
国内免费 | 1篇 |
学科分类
工业技术 | 878篇 |
出版年
2023年 | 3篇 |
2022年 | 19篇 |
2021年 | 18篇 |
2020年 | 17篇 |
2019年 | 22篇 |
2018年 | 22篇 |
2017年 | 23篇 |
2016年 | 25篇 |
2015年 | 19篇 |
2014年 | 30篇 |
2013年 | 48篇 |
2012年 | 29篇 |
2011年 | 47篇 |
2010年 | 34篇 |
2009年 | 41篇 |
2008年 | 36篇 |
2007年 | 37篇 |
2006年 | 33篇 |
2005年 | 31篇 |
2004年 | 24篇 |
2003年 | 34篇 |
2002年 | 13篇 |
2001年 | 11篇 |
2000年 | 14篇 |
1999年 | 18篇 |
1998年 | 64篇 |
1997年 | 35篇 |
1996年 | 25篇 |
1995年 | 13篇 |
1994年 | 12篇 |
1993年 | 12篇 |
1992年 | 5篇 |
1991年 | 6篇 |
1990年 | 3篇 |
1989年 | 4篇 |
1987年 | 4篇 |
1986年 | 3篇 |
1985年 | 2篇 |
1984年 | 5篇 |
1983年 | 4篇 |
1982年 | 3篇 |
1981年 | 4篇 |
1980年 | 2篇 |
1979年 | 5篇 |
1978年 | 3篇 |
1976年 | 7篇 |
1971年 | 1篇 |
1966年 | 1篇 |
1965年 | 1篇 |
1938年 | 1篇 |
排序方式: 共有878条查询结果,搜索用时 15 毫秒
21.
Arnau Vidal Vicente Sanchis Antonio J. Ramos 《Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment》2018,35(3):529-537
The mycotoxin deoxynivalenol (DON) is one of the most common mycotoxins of cereals worldwide, and its occurrence has been widely reported in raw wheat. The free mycotoxin form is not the only route of exposure; modified forms can also be present in cereal products. Deoxynivalenol-3-glucoside (DON-3-glucoside) is a common DON plant conjugate. The mycotoxin concentration could be affected by food processing; here, we studied the stability of DON and DON-3-glucoside during baking of small doughs made from white wheat flour and other ingredients. A range of common food additives and ingredients were added to assess possible interference: ascorbic acid (E300), citric acid (E330), sorbic acid (E200), calcium propionate (E282), lecithin (E322), diacetyltartaric acid esters of fatty acid mono- and diglycerides (E472a), calcium phosphate (E341), disodium diphosphate (E450i), xanthan gum (E415), polydextrose (E1200), sorbitol (E420i), sodium bicarbonate (E500i), wheat gluten and malt flour. The DON content was reduced by 40%, and the DON-3-glucoside concentration increased by >100%, after baking for 20 min at 180°C. This confirmed that DON and DON-3-glucoside concentrations can vary during heating, and DON-3-glucoside could even increase after baking. However, DON and DON-3-glucoside are not affected significantly by the presence of the food additives tested. 相似文献
22.
Fructose overfeeding in first‐degree relatives of type 2 diabetic patients impacts energy metabolism and mitochondrial functions in skeletal muscle 下载免费PDF全文
23.
Phenyl‐γ‐valerolactones,flavan‐3‐ol colonic metabolites,protect brown adipocytes from oxidative stress without affecting their differentiation or function 下载免费PDF全文
24.
Dr. Marine Blanchet Dr. Diane Borselli Dr. Anne Rodallec Dr. Franck Peiretti Nicolas Vidal Dr. Jean‐Michel Bolla Dr. Carole Digiorgio Kelly R. Morrison Prof. William M. Wuest Dr. Jean Michel Brunel 《ChemMedChem》2018,13(10):1018-1027
The emergence of multidrug‐resistant bacteria and pathogens has created an urgent need for the development of new antibiotics. Herein we report our investigations into the broad‐spectrum activity of an easily prepared water‐soluble polyaminosterol compound, namely claramine A1, against both drug‐sensitive and drug‐resistant Gram‐negative and Gram‐positive bacterial strains. We also report its peculiar mechanism of action, which differs from that of all the other well‐known classes of antibiotics, toward Gram‐negative and Gram‐positive bacteria. Given their low cytotoxicity, this class of compounds based on claramine A1 could constitute an effective response to combat the emergence of multidrug‐resistant bacteria and nosocomial diseases. 相似文献
25.
Alberto Gomez-Barea Susanna Nilsson Fernando Vidal Barrero Manuel Campoy 《Fuel Processing Technology》2010,91(11):1624-1633
Experiments were carried out in a laboratory fluidized bed (FB) to characterize the devolatilization behavior of wood and various wastes at temperatures applicable to FB gasification and combustion, i.e. 750-900 °C. The fuels tested were pellets made of wood, meat and bone meal, and compost (from municipal solid wastes), as well as dried granulates of sewage sludge (DSS). Determination of yields of char, condensate and light gas, as well as the composition of the gas and the time of devolatilization during the pyrolysis of single fuel batches was made. A simple model was developed to analyze the mode of conversion of a single wood pellet and DSS granulate, giving insight on the controlling mechanisms during devolatilization. The devolatilization kinetics of DSS was determined by tests using fine granulates. The model was successfully applied to simulate the conversion of large DSS granulates and wood pellets under the whole range of temperatures analyzed. 相似文献
26.
By thermally treating a commercial cellulose in ethylene glycol, celluloses of controlled low degree of polymerization, DPr = 1000 to 70, can be derived. Two general behaviors are observed in the range studied. At first, the depolymerization reaction is predominant down to a DP equal to 130. Beyond this level, the depolymerization process leads to extensive solubilization of the cellulose. The treated celluloses have been analyzed by X-ray diffraction, FTIR, TGA, elemental analysis and enzymatic hydrolysis. No chemical change of the cellulose could explain the two different behaviors. A physical modification in the form of depolymerization and destructuration is suspected. 相似文献
27.
Clarisse Roblin Steve Chiumento Cdric Jacqueline Eric Pinloche Cendrine Nicoletti Hamza Olleik Elise Courvoisier-Dezord Agns Amouric Christian Basset Louis Dru Marie Ollivier Aurlie Bogey-Lambert Nicolas Vidal Mohamed Atta Marc Maresca Estelle Devillard Victor Duarte Josette Perrier Mickael Lafond 《International journal of molecular sciences》2021,22(6)
The world is on the verge of a major antibiotic crisis as the emergence of resistant bacteria is increasing, and very few novel molecules have been discovered since the 1960s. In this context, scientists have been exploring alternatives to conventional antibiotics, such as ribosomally synthesized and post-translationally modified peptides (RiPPs). Interestingly, the highly potent in vitro antibacterial activity and safety of ruminococcin C1, a recently discovered RiPP belonging to the sactipeptide subclass, has been demonstrated. The present results show that ruminococcin C1 is efficient at curing infection and at protecting challenged mice from Clostridium perfringens with a lower dose than the conventional antibiotic vancomycin. Moreover, antimicrobial peptide (AMP) is also effective against this pathogen in the complex microbial community of the gut environment, with a selective impact on a few bacterial genera, while maintaining a global homeostasis of the microbiome. In addition, ruminococcin C1 exhibits other biological activities that could be beneficial for human health, as well as other fields of applications. Overall, this study, by using an in vivo infection approach, confirms the antimicrobial clinical potential and highlights the multiple functional properties of ruminococcin C1, thus extending its therapeutic interest. 相似文献
28.
A. Ontiveros-Ortega F. Vidal E. Gimenez J. M. Ibáñez 《Journal of Materials Science》2014,49(9):3550-3559
We studied the surface properties of eruptive material from Deception Island (South Shetland Islands, Antarctica). The surface free energy and zeta potential were analyzed in obsidian and pumice stones immersed in different electrolytes (NaCl, BaCl2, AlCl3, VCl2, PbCl2, CdCl2, FeCl3, and CrCl3). The results show that obsidian has a monopolar character. The value of the obsidian electron-donor component increased in the presence of heavy metals, reaching 61.0 mJ/m2 in the case of CrCl3. This means that the heavy metals transform the surface of obsidian into a hydrophilic material in almost all cases, except in the case of FeCl3, which makes the obsidian surface hydrophobic. The pH variation of the liquid phase has a significant influence on the zeta potential, not only changing its value, but also the sign of the surface electric charge. A significant result is that a variation of two in pH (between 5 and 7) changes the sign of the charge from positive to negative or vice versa, depending on the electrolyte used. In general, the presence of electrolytes changes the surface properties of solid materials and consequently the adhesion and growth of microorganisms on coastal rocks. 相似文献
29.
Schubert R. Carvalho Ronan Boulic Creto A. Vidal Daniel Thalmann 《The Visual computer》2013,29(3):171-188
We explore an approach to full-body motion editing with linear motion models, prioritized constraint-based optimization and latent-space interpolation. By exploiting the mathematical connections between linear motion models and prioritized inverse kinematics (PIK), we formulate and solve the motion editing problem as an optimization function whose differential structure is rich enough to efficiently optimize user-specified constraints within the latent motion space. Performing motion editing within latent motion spaces has the advantage of handling pose transitions and consequently motion flow by construction from single key-frame editing. To handle motion adjustments from multiple key-frame and trajectory constraints, we developed a latent-space interpolation technique by exploiting spline functions. Such an approach handles per-frame adjustments generating smooth animations, while avoiding the computational expense of joint space interpolations. We demonstrate the usefulness of this approach by editing and generating full-body reaching and walking jump animations in challenging environment scenarios. 相似文献
30.
An electronic panel formed by an electronic nose, an electronic tongue and an electronic eye has been successfully used to evaluate the organoleptic characteristics of red wines vinified using different extraction techniques and micro-oxygenation methods and bottled using closures of different oxygen transmission rates (OTR). 相似文献