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排序方式: 共有1904条查询结果,搜索用时 46 毫秒
1.
Shibo Lv Yuyang Miao Dr. Dapeng Liu Prof. Fengling Song 《Chembiochem : a European journal of chemical biology》2020,21(15):2098-2110
Photothermal therapy (PTT) has attracted great attention due to its noninvasive and effective use against cancer. Various photothermal agents (PTAs) including organic and inorganic PTAs have been developed in the last decades. Organic PTAs based on small-molecule dyes exhibit great potential for future clinical applications considering their good biocompatibility and easy chemical modification or functionalization. In this review, we discuss the recent progress of organic PTAs based on small-molecule dyes for enhanced PTT. We summarize the strategies to improve the light penetration of PTAs, methods to enhance their photothermal conversion efficiency, how to optimize PTAs’ delivery into deep tumors, and how to resist photobleaching under repeated laser irradiation. We hope that this review can rouse the interest of researchers in the field of PTAs based on small-molecule dyes and help them to fabricate next-generation PTAs for noninvasive cancer therapy. 相似文献
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城市空间立体开发已成为国际大都市规划管理的共同理念,城市空间协调开发要求城市边缘机场区域控高指标纳入规划建设统一管理。机场控高区域超高建筑物实况普查为城市先进建设管理理念提供基础数字,是一项重要的工程测量行为。主要介绍超高测量的基本思路及其涵盖的规划信息属性,营造机场空间与城市规划建设协调发展平台。 相似文献
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多泵并联变频给水作为二次供水系统中最主要的运行方式,具有稳定、可靠、节能的优点,但在实际应用中仍会因为工况分析不全面、泵组搭配不佳等问题导致节能效果不尽人意.为此,以二次供水常用的同型号双泵、三泵变频泵组为对象,探究其并联运行工况,提出"过渡低效区"的概念并分析其危害、产生原因及消除方式,借此概念给出了"改用变频大泵+工频小泵"以及"增加变频泵"的两种节能优化措施,推导了两种优化方式在双泵、三泵并联改造中消除"过渡低效区"的判定公式,并将其推广至n台水泵并联形式.最后以一工程实例模拟分析并联泵组优化措施的节能效果,结果表明各类优化方案均比原始方案更加节能,具有一定的实际意义,其中改用"变频大泵+工频小泵"的方式节能性最好. 相似文献
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双目视觉系统在风洞伞摆角测量中的研究与应用 总被引:1,自引:0,他引:1
伞系统是飞行器的重要组成部分,其摆角参数是系统安全性的重要指标之一;针对目前风洞试验中伞摆角难以测量的问题,提出了一种基于双目视觉系统的试验方法,该系统主要由两部CCD相机、图像采集卡和控制计算机组成,通过立体视觉标定和数字图像处理技术解算出空间特征标记的三维坐标,根据坐标的空间几何关系计算出伞摆角参数;试验结果表明该方法应用成功,能够同时获取伞运动过程中投影在正交平面上的竖直和水平摆角,且具有系统组成简单、通用性强的优点,有较高的应用价值。 相似文献
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The diffusion coefficient of a dye in fibres is critical to understanding the dyeing process and coloration quality of products. In this paper, the diffusion kinetics of solvent dyes in the thermosol dyeing of polyester fibres was studied by measuring K / S of the dyed polyester fabrics based on the Kubelka–Munk equation. The diffusion coefficients of two model solvent dyes were estimated with Hill's equation using the experimentally measured K / S values and were found to be in good agreement with those calculated from the traditional extraction method. Such a measurement method was applied to several other solvent dyes and pigments that have different molecular sizes and a good correlation between the measured diffusion coefficients and sizes of these dyes and pigments was found. The results indicate that it is feasible to use K / S measurement of dyed fabrics and Hill's equation to evaluate the kinetics of the thermosol dyeing process under certain conditions. 相似文献
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Experimental Study of an EMG-Controlled 5-DOF Anthropomorphic Prosthetic Hand for Motion Restoration
Dapeng Yang Li Jiang Qi Huang Rongqiang Liu Hong Liu 《Journal of Intelligent and Robotic Systems》2014,76(3-4):427-441
In this paper, we attempted to evaluate the performance of an electromyography (EMG)-controlled 5-DOF prosthetic hand on ten transradial amputees. The proposed prosthesis is composed of a five-fingered hand, a passive wrist, and a customized socket for each subject. The EMG control methods included both a commonly used pattern recognition-based scheme (DD-SVM) and a novel digital encoding strategy (double-channel template matching (DCTM)). A virtual 3D hand platform was developed for training the subjects and rapidly testing the control methods. For each subject, the performance of the EMG control methods was firstly measured by off-line classification accuracy; then, according to the accuracy, a particular control method was selected and embedded in the EMG controller for further validation on ordinary daily life activities. Our experiments were conducted to test not only the hand’s grasp ability but also other multifinger cooperation skills. The result indicated that the subjects of rich control experience can accomplish several intuitive motion control over their hands. However, the kinds of the motions and their relative recognition accuracy may depend on some individual differences, such as the amputation level, the activity of the residual nerve-muscle system, and the richness of control experience. Meanwhile, the proposed digital encoding method, DCTM, which only utilized two channels of EMG, was necessary for those amputees with few available control signals. This paper suggested that the EMG control method should be differently considered according to the particular condition of each subject. 相似文献