浅谈抑郁症之病因病机

抑郁症不能等同于中医郁症,抑郁症的病因病机主要是思虑过度导致肝失疏泄,脾失健运,心失所养,肾精亏虚,脏腑气血功能失调,元神失养。病位在脑,涉及心、肝、脾、肾多脏,中医辨证以虚证为纲。     

浅谈急性胰腺炎之病因病机

急性胰腺炎应与中医的腹痛相似,其病因病机,多由感受六淫之邪、饮食不节、情志失畅、胆石、虫积、创伤等因素引起邪阻气滞,肝胆不利,湿郁热结、蕴于中焦,表现或为肝郁气滞之证,或为肝胆湿热之证,或为胃肠热结之证;病位在脾,与心、肝胆、胃肠有关,中医辨证应以实证为纲。     

老年性痴呆病因病机探析

老年性痴呆是伴随着人类衰老而出现的常见病、多发病。其中阿尔茨海默病（Alzheimer disease,AD）和血管性痴呆（vascular dementia．VD）是两大主要类型。随着世界人口的老龄化,痴呆在老年人的疾病谱和死亡谱中已占有十分重要且突出的地位,并成为老年人群中仅次于心脏病、恶性肿瘤和脑卒中之后的第4位死亡原因,严重威胁中老年人身体健康和生活质量。流行病学调查,老年性痴呆的发病率占老年人的7％～8％,且患病率呈逐年上升趋势。近年来我国上海市和美国多家科研机构联合进行痴呆患病率的调查结果表明,AD是引发痴呆的首位原因,约占2／3。因此,对于老年性痴呆的认识和治疗有着重要的医学和社会意义。     

心衰病中医病因病机探讨

目的：探讨中医对心衰病病因病机的认识,从而更好地认识和理解心衰病的发生原因及病理机制并指导临床治疗。方法：查阅古代文献对心衰病相关症状的描述及病机阐释结合临床观察研究。结果 ：祖国传统医学虽未对心衰进行集中系统论述,但其对心衰病早已有了深刻的认识,认为心气虚是发病基础,气虚血瘀贯穿始终,阴阳失调是病理演变基础,痰饮水停则是其最终产物。结论：心衰乃本虚标实之证,本虚为阳虚、气虚、阴虚,标实为血瘀、痰饮、水停,标本俱病,虚实夹杂。     

老年性痴呆病因病机探析

老年性痴呆是伴随着人类衰老而出现的常见病、多发病.其中阿尔茨海默病(Alzheimerdisease, AD)和血管性痴呆(vascular dementia, VD)是两大主要类型.随着世界人口的老龄化,痴呆在老年人的疾病谱和死亡谱中已占有十分重要且突出的地位,并成为老年人群中仅次于心脏病、恶性肿瘤和脑卒中之后的第4位死亡原因,严重威胁中老年人身体健康和生活质量.     

论“湿邪致中风”

中风病是难治性脑病,历代医家对中风病病因病机观点各异。立足于湿邪和中风病的古今文献研究,结合湿邪致病的特点和中风病的证候特点,探讨湿邪与中风病之间的关系,剖析“湿邪致中风”的源流、辨证要点及临证思路,强调湿邪为中风病的重要病理因素,以期加深临床上对中风病的研究,进一步拓宽治疗思路。     

艾滋病中医病因病机研究进展

艾滋病于1981年在美国同性恋者中首先发现。1982年9月24日,美国疾病控制中心(CDC)正式提出了获得性免疫缺陷综合征(acqu ired immunodefic iency syndrom e,AIDS)的概念,指出艾滋病是不明原因的细胞免疫缺陷所导致的卡波肉瘤、卡氏肺囊虫肺炎和其他严重的机会性感染[1-2]。1986     

小儿癫痫病因病机探微

《五十二病方》“婴儿病痫方”,是中医学史上有关“痫”的最早记载。《黄帝内经》中与痫证相关的病名多达9种,突出患者痫发时躯体动作异常的特征。唐代《备急千金要方》首次提出癫痫的病名。至宋代《幼幼新书》列癫痫专条。历代医家对于癫痫病因的认识,多责之于“热”“惊”“痰”,临床上多为诸型交错互见。癫痫病位在脑、肝、心、脾、肾。气机失调贯穿癫痫全病程,而痰热互结是癫痫的关键病机,此外,风火相盛、气虚生惊、邪毒入络、瘀血阻窍是癫痫的常见病机。发作期以心肝失调、逆气上冲为主,休止期脏腑失和、邪气潜伏,恢复期脏腑气血基本调和,余邪未尽。     

酒疸病因病机浅析

古代医家对酒疸病因的认识以酗酒为主因,而诱固很多,有外感、饮食、睡眠、体质和劳役5种因素。酒疸的形成是这些因素综合作用的结果。病机不离湿热。形成的关键是小便不利。发黄的机理历代有不同的认识,湿热郁蒸。病久既可形成瘀血,又可导致阳虚。     

运动神经元病的中医病因病机探讨

从运动神经元病的中医病名、病因病机探究入手,认为脾肾肝三脏虚损是本病发病的内在原因,湿浊之邪是其重要的致病因素,毒邪侵犯是重要病因,瘀血既是病理产物又是致病因素,络病是其缠绵难愈的主要机制,虚风内动是本病进展的重要病理环节.     

深部念珠菌感染的病原学特征

目的:了解近年来深部念珠菌感染的病原学特征。方法:使用常规方法鉴定念珠菌,包括接种于CHROM agar念珠菌显色培养基、玉米-吐温80培养基及血清,通过菌落、显色特征、芽管试验、厚膜孢子、假菌丝等形态学观察以及商品试剂盒包括API 20C AUX和VITEK YBC生化卡鉴定菌种;血培养使用VITAL血培养检测仪。结果:2004年5月~2007年4月3年间从深部标本中共分离念珠菌749株,菌种分布情况为:白念珠菌41.79%、热带念珠菌24.17%、光滑念珠菌12.02%、近平滑念珠菌12.95%、克柔念珠菌2%、其他念珠菌7.07%。结论:白念珠菌所占比例仍然最高,但较前阶段有所下降。光滑念珠菌和克柔念珠菌所占比例明显上升。     

Etiological study on cystitis glandularis caused by bacterial infection

Summary To study the relationship between bacterial infection and the etiology of cystitis glandularis, 36 female Wistar rats were divided into 3 groups. No intervention was given to the rats in the blank group. NS was infused into the bladder of the rats of the control group, and solution containing E. coli was injected into the bladder of experimental group. Three months later, tissue samples of bladder were collected and observed visually and under light microscope. The results showed that tissues of the blank group were normal; one sample in the control group showed Brunn’s nests and cystitis cystica, and 10 in the experimental group had the change of cystitis glandularis. Compared to the blank and control group, samples in the experimental group showed significant change (P<0.05). There were no significant difference between blank group and control group (P>0.05). It is concluded that bladder instillation of E. coli can induce cystitis glandularis, which confirms that infection is the cause of cystitis glandularis. This project was supported by grants from the Hubei Province Natural Sciences Foundation (No.2005ABA164).     

Etiological Study on Cystitis Glandularis Caused by Bacterial Infection

To study the relationship between bacterial infection and the etiology of cystitis glandularis, 36 female Wistar rats were divided into 3 groups. No intervention was given to the rats in the blank group. NS was infused into the bladder of the rats of the control group, and solution containing E. coil was injected into the bladder of experimental group. Three months later, tissue samples of bladder were collected and observed visually and under light microscope. The results showed that tissues of the blank group were normal＇, one sample in the control group showed Brunn＇s nests and cystitis cystica, and 10 in the experimental group had the change of cystitis glandularis. Compared to the blank and control group, samples in the experimental group showed significant change （P〈0.05）. There were no significant difference between blank group and control group （P〉0.05）. It is concluded that bladder instillation of E. coil can induce cystitis glandularis, which confirms that infection is the cause of cystitis glandularis.     

新生儿心律失常的病因分析

目的:探讨新生儿心律失常病因。方法:回顾性分析收治的48例新生儿心律失常的类型、病因。结果:新生儿心律失常类型主要为室上性心律失常占64.5%,各种类型的传导阻滞占16.7%,而室性心律失常仅占10.5%,复合性心律失常占8.3%。心肌酶谱测定,其中18例正常,24例升高。心律失常主要病因为:围生期缺氧、感染、先天性心脏病、电解质紊乱及低血糖。结论:加强围生期保健,减少宫内缺氧,防止低血糖及电解质紊乱,避免孕期感染,可降低新生儿心律失常的发病率。     

基层不同年龄段已婚妇女妇科病普查结果分析

目的 了解基层不同年龄段已婚妇女妇科疾病的患病情况与疾病发展趋势,为开展妇科病的防治工作提供依据.方法 随机抽取昌黎县已婚妇女妇科病5000例普查结果进行分析,检查项目包括妇科检查、白带常规化验、宫颈细胞学检查,盆腔B超检查,对妇科检查可疑者行阴道镜检查,阴道镜异常者行病理组织学检查.结果 5000名受检者中查出患妇科病总人数3892例,患病率为81.50％.妇科常见病中慢性宫颈炎发病率居首位为2415例,患病率48.30％;其次为阴道炎2245例,患病率44.90％;子宫肌瘤188例,患病率3.76％;附件包块89例,患病率1.75％;盆腔积液80例,患病率1.58％;前庭大腺囊肿7例;宫颈癌前病变4例;确诊早期宫颈癌3例.慢性宫颈炎、阴道炎的发病与年龄有关,30～50岁年龄段患病率最高,分别为46.11％,30.43％,随年龄增长而下降（P＜0.01）.子宫肌瘤25～30岁患病率为1.32％,随年龄增长而上升,但绝经后降至1.00％.结论 生殖道感染是影响妇女健康的主要疾病,重视妇科病普查,系统规范地治疗妇科常见病,对高发年龄段的妇女进行重点干预,是实现妇科疾病三早（早发现、早诊断、早治疗）和降低两率（患病率、死亡率）的关键,亦是妇女保健面临的重要任务.     

Correlation between pathogenesis of dampness syndrome and Interleukin-2,Interleukin-8 in rats

OBJECTIVE: To explore the pathogenesis of dampness syndrome by detecting the changes of interleukin-2 (IL-2) and interleukin-8 (IL-8) levels. METHODS: Female Sprague Dawley rats were divided randomly into five groups according to the random number table: a normal group (GroupⅠ), an external dampness group (GroupⅡ), an internal dampness group (Group Ⅲ), and an external and internal dampness group (GroupⅣ). Twenty days after the model made, IL-2 and IL-8 levels were detected by radioimmunoassay method. RESULTS: The IL-2 and IL-8 levels among groups were significant (F=3.102, P<0.05; F=2.657, P<0.05, respectively). The level of IL-2 in Group Ⅱ and Group Ⅲ were higher than that in GroupⅠ(P<0.05, P<0.01, respectively), especially higher in the Group Ⅲ compared with GroupⅡ (P<0.05). The lev- el of IL-8 in Group Ⅲ were higher than those inGroupⅠ, GroupⅡ and GroupⅣ (P<0.05, P<0.01, P< 0.05, respectively). In the GroupⅢ, the 24-hour wa ter and body weight were higher than that in the GroupⅣ (all P<0.05), and spontaneous movemen frequency was higher than those in GroupⅡ and GroupⅣ (P<0.05). CONCLUSION: Immune activation and inflammato ry reaction might be easily caused by externa danpness other than internal dampness.     

一起多型别副溶血性弧菌引起的食物中毒病原学研究

目的对一起由多种血清型副溶血性弧菌引起的食物中毒病原菌进行毒力基因及分子分型研究。方法参照国家标准方法对事件中可疑样品进行病原菌分离鉴定,对分离的副溶血性弧菌进行血清学试验,采用荧光定量PCR检测菌株的毒力基因耐热直接溶血素基因（tdh）、耐热直接溶血素相关溶血素基因（trh）与不耐热溶血素基因（tlh）,并用脉冲场凝胶电泳（PFGE）对分离到的菌株进行分子分型。结果从24份病人标本和1份剩余食品中检出副溶血性弧菌25株;血清型分布为O4：K8 4株,O3：K6 19株,O4：KUT 1株和O3：KUT 1株;分离到的25株副溶血性弧菌毒力基因检测均为tdh＋tlh＋trh-;PFGE聚类分析显示,不同血清型菌株分为不同的簇,同一血清型菌株的PFGE条带型间存在1~2个条带的差异,菌株间存在关联。结论这是一起由多种血清型副溶血性弧菌引起的食物中毒。     

女工妇科病13 512例普查情况分析

目的了解普查普治对女工妇女病防治的意义。方法对4年来13512例女工妇科病复查普治进行分析。结果妇科疾病患病率在逐年下降,由2001年的48.17%下降到2004年的30.1%。常见的妇科疾病是慢性子宫颈炎,念珠菌阴道炎及附件炎。结论定期妇女病普查普治可降低妇女病的发病率,但有待探讨常见妇女病新的防治措施。     

"黄家所得,从湿得之"对胎黄的启发

从《金匮要略》之“黄家所得,从湿得之”中得到启发,论述了该句对新生儿黄疸病因、病机及治疗的启示。进一步探讨张仲景时代对黄疸的认识与现代认识的差异并阐明自己的观点。     

动脉狭窄引起血流动力学的变化及影响因素

长期以来,众多学者通过从体外实验到体内实验及临床观察,并不断改进实验装置及方法,研究狭窄所引起的血流动力学改变及评价方法,为动脉狭窄的诊断及治疗提供了依据.