新型纳米级聚酯纤维

通过采用众多纺丝技术,对纤维的结构控制已从微米级发展到纳米级。对纳米级纤维结构控制的重要性可以用两个方法来说明。一是给出模型或概念用以改善如结晶尺寸和分子取向这样的物理性质。这种方法是将宏观性能与纳米级结构联系起来,对聚合物设计和纤维结构来说是非常重要的。另一个方法是关于纳米纤维本身。此次研究将展现纳米纤维拥有哪些新的或者说优越的性能。     

白及提取物乳膏剂的处方筛选研究

考察白及提取物白及胶最佳提取工艺,制备白及胶乳膏剂。采用水提醇沉法提取白及胶,结合正交设计法优选最佳的提取方案;采用单因素考察的基础上,以外观性状及稳定性为指标,采用多因素优化基质处方,在离心、高温、冷藏条件下考察基质处方中各组分对乳膏剂成型的影响,确定乳膏剂的基质处方组成;并对优选的最佳含药乳膏进行质量检查。白及胶的最佳提取工艺为料液比1∶10、水提取3次,3倍量95%乙醇醇沉;白及胶乳膏剂的最佳制备工艺为每100 g白及乳膏剂中含白及胶5 g、硬脂酸5 g、高级脂肪醇1 g、卡波姆0. 2 g、三乙醇胺1 g、司盘-60 1 g、蜂蜡4 g、二甲基硅油1 g、棕榈酸异丙酯1 g、尼泊金乙酯0. 2 g加水适量于80℃下乳化15 min。制备的白及胶乳膏剂,稳定性良好,外观性状合格,为乳膏剂的开发提供了参考。     

染发剂乳膏稳定性的研究

本提出了一种能提高对苯二胺型染发剂贮存稳定性的Ｗ／Ｏ／Ｗ复合乳膏的制备方法。并了这种乳膏稳定性的影响因素。     

储氢气用新型纳米级复合聚合物材料

美国伯克利国家实验室的研究人员开发出一种新型聚合物纳米复合材料,他们相信这一成果代表了储氢技术的重大突破。氢气清洁,唯一的燃烧副产品是水,因此长期以来被视为理想的化石燃料替代能源。但是,氢气很难安全储存以及高密度压缩。     

储氢气用新型纳米级复合聚合物材料

美国伯克利国家实验室的研究人员开发出一种新型聚合物纳米复合材料,他们相信这一成果代表了储氢技术的重大突破。氢气清洁,唯一的燃烧副产品是水,因此长期以来被视为理想的化石燃料替代能源。但是,氢气很难     

静电纺丝制备纳米级纤维的研究

首先介绍了静电纺丝制备纳米纤维的原理及其影响因素,然后归纳、总结了当前国内外静电纺丝制备纳米纤维的研究内容,并对今后的研究提出了建设.     

纳米级CaCO3填充LDPE复合材料的研究

研究了高分子表面处理剂处理纳米CaCO3填充LDPE复合膜的力学性能。结果表明，由于纳米粒子的表面效应以及高分子表面处理剂的作用，加入少量的纳米粒子，复合体系的拉伸强度、断裂伸长率和直角撕裂强度均有不同程度的增加。     

一种新型纳米级二氧化钛光稳定剂DLS210

介绍了一种新型纳米级二氧化钛光稳定剂,即美国杜邦公司光稳定剂DLS210的基本性能、目前存在的问题及其应用前景。     

多乳状液一种新型化妆品体系

多乳状液体系可被视为一种最为合适的化妆品体系,它可以将有效成分分别溶入多乳状液体系的不同组成相中,并对各有效成分进行缓慢释放。讨论了多乳状液的制备原理并给出几个近来多乳状液研究中得到的稳定体系的例子、多乳状液体系的物理稳定必、粘弹性以及应用前景也将得到一定阐述。     

Analysis of a Novel Nanoscale Vacuum Channel TF-FinFET

Silicon - Concerned work is solely dedicated to the optimized characteristics of Nanoscale vacuum channel TF (Truncated fin)-FinFET at gate length of 7 nm. NVCTF-FinFET has its own...     

Novel Formulation of Undecylenic Acid induces Tumor Cell Apoptosis

Undecylenic acid, a monounsaturated fatty acid, is currently in clinical use as a topical antifungal agent, however the potential for therapeutic application in other disease settings has not been investigated. In this study, we describe a novel platform for the solubilization of fatty acids using amino acids and utilize this approach to define a tumoricidal activity and underlying mechanism for undecylenic acid. We examined a novel formulation of undecylenic acid compounded with L-Arginine, called GS-1, that induced concentration-dependent tumor cell death, with undecylenic acid being the cytotoxic component. Further investigation revealed that GS-1-mediated cell death was caspase-dependent with a reduction in mitochondrial membrane potential, suggesting a pro-apoptotic mechanism of action. Additionally, GS-1 was found to localize intracellularly to lipid droplets. In contrast to previous studies where lipid droplets have been shown to be protective against fatty acid-induced cell death, we showed that lipid droplets could not protect against GS-1-induced cytotoxicity. We also found a role for Fatty Acid Transport Protein 2 (FATP2) in the uptake of this compound. Collectively, this study demonstrates that GS-1 has effective pro-apoptotic antitumor activity in vitro and, together with the novel platform of fatty acid solubilization, contributes to the re-emerging field of fatty acids as potential anti-cancer therapeutics.     

Novel Nanoscale Ceria–Platinum Composite Electrodes for Direct Alcohol Electro-Oxidation

A nanocrystalline Pt/CeO₂ composite electrode is fabricated to study the electrochemical oxidation of methanol and ethanol. Three different methods have been developed for the preparation of the composite electrode and are compared in terms of their oxidation efficiencies. In general, all the electrode preparation methodologies show a great enhancement of the oxidation current for the alcohol. However, methods based on the electrodeposition of a ceria rich Pt matrix show the greatest effectiveness of alcohol oxidation. The enhancement of the anodic current is dependent on the particle loading and size distribution in the composite matrix. In general, ceria appears to be an effective alternative to ruthenium in direct alcohol fuel cells.     

纳米隔热膜的研究

本文研究了UV固化组分、纳米金属氧化物ATO粒径和涂布厚度与薄膜隔热性能的关系。结果表明,光固化隔热涂层性能与UV固化组分的官能度、光引发剂用量、纳米金属氧化物的用量和纳米材料粒径有密切关系。合理的隔热涂层组分,能得到满意的纳米涂布隔热薄膜。     

农药水乳剂的研究

对水乳剂的原理、制作条件、加工工艺作了阐述,提出了试验中出现的问题并对水乳剂的市场前景进行了展望。     

Formulation,Characterization and Cytotoxicity Effects of Novel Thymoquinone-PLGA-PF68 Nanoparticles

Thymoquinone has anti-cancer properties. However, its application for clinical use is limited due to its volatile characteristics. The current study aims to develop a polymeric nanoformulation with PLGA-PEG and Pluronics F68 as encapsulants to conserve thymoquinone’s (TQ) biological activity before reaching the target sites. Synthesis of nanoparticles was successfully completed by encapsulating TQ with polymeric poly (D, L-lactide-co-glycolide)-block-poly (ethylene glycol) and Pluronics F68 (TQ-PLGA-PF68) using an emulsion–solvent evaporation technique. The size and encapsulation efficiency of TQ-PLGA-PF68 nanoparticles were 76.92 ± 27.38 nm and 94%, respectively. TQ released from these encapsulants showed a biphasic released pattern. Cytotoxicity activity showed that tamoxifen-resistant (TamR) MCF-7 breast cancer cells required a higher concentration of TQ-PLGA-PF68 nanoparticles than the parental MCF-7 cells to achieve IC₅₀ (p < 0.05). The other two resistant subtypes (TamR UACC732 inflammatory breast carcinoma and paclitaxel-resistant (PacR) MDA-MB 231 triple-negative breast cell line) required a lower concentration of TQ-PLGA-PF68 nanoparticles compared to their respective parental cell lines (p < 0.05). These findings suggest that TQ encapsulation with PLGA-PEG and Pluronics F68 is a promising anti-cancer agent in mitigating breast cancer resistance to chemotherapeutics. In future studies, the anti-cancer activity of TQ-PLGA-PF68 with the standard chemotherapeutic drugs used for breast cancer treatment is recommended.     

纳米Ag-TiO2/ITO光催化膜的制备、表征及光催化活性的研究

用直接光还原法将Ag+沉积到TiO2膜表面制备了纳米Ag TiO2/ITO光催化膜,该光催化膜分别用紫外可见光漫反射、X射线衍射、扫描电镜进行了表征;并以甲酸为模型化合物,研究了Ag TiO2/ITO光催化膜对有机污染物的光催化氧化降解。实验结果表明:沉积于TiO2膜表面的银是以Ag(0)形式存在,且Ag可以作为光生电子载体,对抑制光生电子-空穴的复合有明显的促进作用,但Ag TiO2/ITO膜的光催化活性与Ag的沉积量密切相关,其中以Ag沉积质量分数为1 1%的Ag TiO2/ITO膜的光催化活性最佳,其光催化氧化甲酸的速率常数约为TiO2/ITO膜光催化速率常数的2 2倍。     

A Novel Aerosol Combustion Process for the High Rate Formation of Nanoscale Oxide Particles

We report a new method for the high rate formation of nanophase ZrO₂ and Al₂O₃     

琥珀酸舒马曲坦的剂型研究

偏头痛是一种常见病、多发病.琥珀酸舒马曲坦是治疗偏头痛的最有效的药物之一.此类药物的制剂常用的有口服片剂、皮下注射剂,现又发展了一些新的剂型如口服制剂、浑悬液、透皮吸收剂及鼻喷雾剂,使给药的途径更为多样化.其中非口服用药途径适合吞咽困难或不喜欢吞咽的患者,以及伴有恶心、呕吐的偏头痛患者.尤其鼻喷雾剂,可以随时随地使用,在偏头痛刚刚发作时及时治疗,将成为偏头痛患者理想的一线药物.