卵巢外腹膜浆液性乳头状癌五例临床分析

卵巢外腹膜浆液性乳头状癌五例临床分析张国楠孙维纲彭莉余建樊英陈毅男卵巢外腹膜乳头状浆液性癌（ＥＰＳＰＣ）系原发于腹膜表面、双侧卵巢正常大小、无肿瘤浸润或仅表面有微小浸润，组织学特征与卵巢乳头状浆液性癌相类似的恶性肿瘤［１～３］。ＥＰＳＰＣ少见，１９５...     

卵巢外腹膜浆液性乳头状癌1例

患者52岁,住院号35148,孕2产2,因腹胀半个月于2002年3月22日入院,绝经2年余。患者于半个月前自觉腹胀明显,腹围增长快,并伴食欲不振,恶心,无腹痛,无阴道不规流血及排液,体重无变化,来我院就诊,以“腹水原因待诊”收住消化内科,CT及彩超检查示恶性腹水,双侧卵巢大小约2.6cm×2.2cm×2.0cm,请我科会诊,再行腹水细     

卵巢外腹膜浆液性乳头状癌

卵巢外腹膜浆液性乳头状癌（ｅｘｔｒａｏｖａｒｉａｎｐｅｒｉｔｏｎｅａｌｓｅｒｏｕｓｐａｐｉｌａｒｙｃａｒｃｉｎｏｍａ，ＥＰＳＰＣ）常表现为腹胀、腹水、纳差等消化道症状，而消化系统往往找不到原发病灶，易延误诊断和治疗，且术后常误诊为卵巢癌。本文对ＥＰ...     

卵巢外腹膜浆液性乳头状癌的临床及病理学分析

目的；分析卵巢外腹膜浆液性乳头状癌的临床及病理学特点。方法：自１９８０年至１９９４年诊治的８１例卵巢浆液性乳头状癌中，选择其中１０例卵巢间质无肿瘤恶性浸润或纱及卵巢表面上皮，而腹膜有病变的卵巢外腹膜浆液性乳头状瘤，地其进行回顾性分析，并进行组织高碘酸－希夫（ＰＡＳ）、奥辛蓝染色，应用免疫组织化学方法检测癌胚抗原（ＣＥＡ），细胞角蛋凶隆抗体ＡＥ１、ＡＥ３、及电镜检查。结果：本组患乾发病年龄为４６－７     

卵巢外腹膜乳头状浆液性癌

卵巢外腹膜浆液性头状癌是原发于腹膜表面、双侧卵巢正常或仅表面有微小浸润、组织学形态相似于卵巢乳头状浆液性腺癌的恶性肿瘤。其经病率约占卵巢浆液性癌的７％－１５％，但迄今文献报道不足３００例，本文综述了ＥＰＳＰＣ的命名，组织来源，临床表现，病理特征及组织学诊断标准，免疫组化，治疗和预后。     

卵巢外腹膜浆液性乳头状腺癌

2005年6月17日下午在北京大学肿瘤医院就卵巢外腹膜浆液性乳头状腺癌（extraovarian peritoneal serous papillary carcinoma，EPSPC）进行专题讨论会。会议特邀中国人民解放军总医院病理科陈乐真教授、北京大学人民医院妇科魏丽惠教授、崔恒教授、病理科沈丹华教授、北京协和医院妇产科沈铿教授、北京大学第一医院妇产科廖秦平教授参会。北京大学各附属医院和北京市其他医院约50余名医生参加了会议。北京大学肿瘤医院妇科高雨农主任主持会议。     

卵巢外腹膜浆液性乳头状癌的研究及诊治进展

卵巢外腹膜浆液性乳头状癌是一种独立的肿瘤,临床发病率低,可能为多灶起源。术前难与卵巢浆液性乳头状癌鉴别,确诊须根据术中所见和术后病理诊断,其治疗和卵巢浆液性乳头状癌相同。     

卵巢外腹膜浆液性乳头状癌误诊一例并文献分析

正卵巢外腹膜浆液性乳头状癌(extiraovarian peritoneal scrolls papillary carcinoma,EPSPC)是一种罕见的恶性肿瘤,又称为原发性腹膜癌(primary peritoneal carcinoma,PPC)。其在组织学上与卵巢原发性浆液性乳头状癌难以区分,具有相似的临床特征、扩散模式、对治疗的反应及存活率。有文献报道,EPSPC女性患者除了诊断年龄较大、肥胖及Ⅲ或Ⅳ期患者淋巴结扩散率增加之外,与上皮性卵巢癌女性具有相似的表观上的生物学特征~([1])。本文系统性分析1例EPSPC,以期提高临床医生对此病的认识。     

腹膜浆液性乳头状癌9例分析

目的 分析卵巢外腹膜浆液性乳头状瘤的临床特点,诊治及预后。方法 选自１９９５年１月至１９９８年１２月在我院收治的９例ＥＰＳＰＣ病人,对其病例资料进行回顾性分析。结果 所有病人均行肿瘤细胞减灭术,术中腹腔放５－ＦＵ１．０ｇ。术后行ＣＡＰ化疗６￣８个疗程。９例中２例正在化疗,２例复发且正在化疗,５例死亡。平均存活期２１．１个月。结论 ＥＰＳＰＣ为女性腹膜原发恶性肿瘤,与卵巢乳头乐液性腺癌同源,其预后与     

12例腹膜原发性浆液性乳头状癌临床诊治分析

目的探讨腹膜原发性浆液性乳头状癌的临床特点、诊断标准、治疗方法和预后。方法对1997年1月-2004年12月在我院经病理确诊为腹膜原发性浆液性乳头状癌的12例患者的临床资料进行回顾性分析。结果所有患者均行肿瘤细胞减灭术，术后施以铂类为主的化疗方案。生存期大约20个月的患者均接受6次以上化疗，术前接受化疗的患者的平均生存期大于28．3个月，较术前未行化疗者生存期长。结论腹膜原发性浆液性乳头状癌是一种起病隐袭，发病率较低的恶性肿瘤，易被误诊。明确的诊断、术前化疗、手术的彻底性及术后足量的化疗可以延长患者的生存期。CA125可作为诊断及监测预后的指标之一。     

Nonimmunologic hydrops fetalis: a review of 11 cases

Eleven cases of nonimmunologic hydrops fetalis occurring during a six year period were reviewed. The etiology of hydrops fetalis was established only in four cases. It included one case of endocardial fibrosis, two cases of non-immunologic hemolysis and one case of tachycardia. The pregnancies were complicated by polyhydramnios in 9 cases, preterm delivery in 10 cases, twins in 3 cases and pre-eclampsia in one case. Four of 11 fetuses died in utero, on one of them, intrauterine blood transfusion and administration of digoxin and furosemide was carried out. Five fetuses died neonatally and two survived. In one of the later cases, intravenous administration of digoxin with quinidine to the mother was without effect, nor did such treatment cause any effect on the neonate after delivery. Electric cardioversion supplemented with digoxin slowed the neonatal cardiac rhythm to normal range with later successful outcome. Earlier diagnosis by ultrasonography especially in cases of hydramnios and appropriate treatment are likely to improve this outcome.     

Solitary cerebellar metastases: analysis of 11 cases.

Solitary cerebellar metastatic tumors are rarely reported in the literature. We reviewed 240 posterior fossa tumors treated in the past eight years. There were 11 cases of solitary metastases in the cerebellum. The primary tumor was lung cancer in five cases and breast carcinoma in two cases; the remaining three cases had colon cancer, nasopharyngeal carcinoma (NPC) and Ewing's sarcoma, respectively. All patients underwent craniectomy and gross total excision of the tumor. Seven patients survived less than one year, two cases died in the second year, and one case of NPC survived for more than two years. The only survival is a case of Ewing's sarcoma who underwent surgery 14 months ago. The symptoms and signs of all patients improved satisfactorily after surgery. Four patients received postoperative irradiation to the posterior fossa and two cases of lung cancer had a thoracotomy for the primary lung lesion; however, the survival period was not prolonged. We suggest that a cancer patient or a patient in the fifth to seventh decades of life presenting headache, gait disturbance and vomiting should promptly undergo a computed tomography (CT) scan of the head. In selected cases, surgical intervention for solitary metastatic tumors in the tiny posterior fossa may be the best initial treatment. Adjuvant therapies should then be added according to the type of tumor.     

Vitrified human day-7 blastocyst transfer: 11 cases

This case report describes successful pregnancies after vitrification of human day-7 blastocysts. A total of 16 day-7 blastocysts were vitrified and warmed. All 16 blastocysts survived after warming and were transferred to 11 patients. Six of the women (55%) became clinically pregnant and the implantation rate was 44% (7/16). Among these women, one woman delivered a healthy baby, two pregnancies ended in miscarriage, and three pregnancies are ongoing at 10, 29 and 34 weeks of gestation. This is the first report of successful pregnancies after vitrification of human day-7 blastocysts.     

Mandibular asymmetry and breastfeeding problems: experience from 11 cases.

The authors review the experiences of 11 mother-infant pairs who had breastfeeding problems related to the infants' mandibular asymmetry. Lower jaw asymmetry is an early identifiable sign of torticollis, and a possible contributor to latch difficulties, nipple pain, and poor milk transfer. Pediatricians and lactation consultants should look for signs of lower jaw asymmetry combined with a preference for turning the head to one side in newborns who present with breastfeeding difficulties. By recognizing these anatomic irregularities early in the course of breastfeeding, pediatric health care providers will be able to treat breastfeeding problems promptly and proactively. They will be able to avoid unnecessary hospital admissions for dehydration symptoms or a septic workup and will intervene quickly with the recommendation of breast pumping and complementary feeding if milk transfer is not occurring.     

Primary carcinoma of the fallopian tube: study of 11 cases

OBJECTIVE: Primary fallopian tube carcinoma is a rare tumor that histologically and clinically resembles primary ovarian carcinoma. The purpose of this study was to present the experience of the Soroka Medical Center (SMC), Beer-Sheva, Israel of handling this tumor. STUDY DESIGN: Data from the files of 11 patients with primary fallopian tube carcinoma who were managed at the SMC between January 1978 and December 1998 were evaluated. RESULTS: The mean age of the patients was 59.4 years. Presenting symptoms and signs included abdominal pain, postmenopausal bleeding, watery vaginal discharge and adnexal mass. In all patients, the diagnosis of primary fallopian tube carcinoma was not made preoperatively. In ten patients in whom the adnexal mass was discovered preoperatively it was thought to be an ovarian tumor and in one patient the adnexal mass was first noticed during vaginal hysterectomy. Postoperatively, multi-drug chemotherapy was given to seven patients, multi-drug chemotherapy followed by pelvic radiotherapy to one patient, pelvic radiotherapy followed by single-agent chemotherapy to two patients, and one patient received no further treatment. The actuarial 5-year survival rate was 50%. CONCLUSIONS: Fallopian tube carcinoma is rarely suspected preoperatively. The symptom complex of 'hydrops tubae profluence', said to be pathognomonic for this tumor, is rarely encountered. The treatment approach is similar to that used for ovarian carcinoma and includes primary surgery comprised of total abdominal hysterectomy, bilateral salpingo-oophorectomy and staging followed by chemotherapy. The prognosis of patients with primary fallopian tube carcinoma is similar to that of patients with primary ovarian carcinoma.     

Imported case of malaria in Taiwan: analysis of 11 cases]

The "eradication of malaria" in Taiwan was announced by WHO in 1965. From 1966 to 1989, 919 malaria cases were detected in Taiwan. Of these cases, 803 were classified as imported malaria. During 1977 to 1989, our hospital collected 11 cases of imported malaria, 6 of Plasmodium falciparum (PF), including 1 suspicious case, 2 of Plasmodium vivax (PV), 1 of mixed infection (PF plus PV), and 2 unclassified. Most of the patients presented clinically with fever and chills. Hepatosplenomegaly was the most common abnormal finding during the physical examination. Jaundice and anemia occurred in the more severe cases. No cases had lymphadenopathy which is helpful in making a differential diagnosis. Six cases had thrombocytopenia which may be considered as an indirect sign in the diagnosis. The MCV levels were within normal limits in all of the cases. This may indirectly imply a potential protective effect against malaria infection in cases of congenital hemoglobinopathy such as thalassemia or G6PD deficiency. Initially, 10 cases were given "standard treatment", which consisted of chloroquine 450 mg qd for 2 days then 300 mg qd for 2 days and primaquine 15 mg qd for 2 weeks. Four cases of chloroquine resistance were encountered, all in cases with PF infection. Two cases were grade I delayed type resistance and were successfully treated with Fansidar, tetracycline and quinine. Two cases were grade II resistance and presented clinically as cerebral malaria. Intravenous quinine was given plus Fansidar and tetracycline. The cases were resolved without sequele or recurrence. None of the cases, except for 2, received chemoprophylaxis.(ABSTRACT TRUNCATED AT 250 WORDS)     

会阴子宫内膜异位症的临床分析

目的：探讨会阴子宫内膜异位症（内异位）的诊断和处理。方法：对1院1983－2000年收治的11例会阴内异症病例进行回顾性分析,术后随诊0．5－7．0年。结果：会阴内异症占我院同期内异症的0．37％,我院会阴内异症发生率为0．87／万。根据临床表现及病理检查,11例均诊断正确。除1例外,均有会阴撕裂或侧切史;发病潜伏期,30岁以前多在1年以内,30岁以上多在1年以上,两者差异有显著性（P＜0．05）。会阴内异症病灶完整切除10例,随诊6个月至7年,无复发。结论：根据典型的病史和身体检查,可以对会阴切口内异症做出正确诊断;手术切除为主要治疗方法。