随机优化问题基于假设检验的遗传算法

为了有效解决具有不确定性和多极小性的随机优化问题 ,提出了一类基于假设检验的遗传算法 .该方法通过多次评价来进行解性能的合理估计 ,利用遗传操作来进行解空间的有效搜索 ,采用假设检验来增加种群的多样性和算法的探索能力 ,从而避免遗传算法的早熟收敛 .基于典型的随机函数优化和组合优化问题 ,仿真研究了假设检验、性能估计次数、噪声幅度对算法性能的影响 ,验证了所提方法的有效性和鲁棒性     

若干多重Mycielski图的邻点可区别Ⅰ-全色数

根据路和星、圈的多重Mycielski图的结构性质,用穷染递推的方法,讨论了图Mn(Cm)和Mn(Pm),以及Mn(Sm)的邻点可区别I-全染色,得到了图Mn(Sm)和Mn(Pm)的邻点可区别I-全色数等于它们的最大度,图Mn(Cm)的邻点可区别I-全色数在m=4,5时等于它的最大度加1,其余情况等于它的最大度,即分别给出图Mn(Sm)和Mn(Cm)、Mn(Pm)一种染色方案。     

Exercise thermoregulation and hyperprolactinaemia

The anterior pituitary hormone prolactin (PRL), measured in the peripheral blood circulation, reflects alterations in central brain 5-hydroxytryptamine (serotonin) and dopaminergic activity and is used as a marker of 'central fatigue' during active heat exposure. Significant correlations have consistently been found between PRL and core temperature (T(CORE)) during prolonged exercise. There has been no investigation into the relationship between PRL and other key thermoregulatory variables during exercise, such as weighted mean skin (T(SK)) and mean body temperature (T(B)), heat storage (HS), thermal gradient (T(GRAD)), heart rate (HR) and skin blood flow (cutaneous vascular conductance, CVC). Therefore, the aim of this study was to ascertain if a significant relationship exists between PRL and these thermoregulatory variables during prolonged exercise. Nine active male subjects conducted three trials of approximately 60% VO(2peak) at 70-80 rpm for 45 min on a semi-recumbent cycle ergometer at three different ambient temperatures [6 degrees C (Cold), 18 degrees C (Neutral) and 30 degrees C (Hot)] to elicit varying levels of thermoregulatory stress during exercise. Significant differences existed in T(SK), T(B), HS, T(GRAD) and CVC across the environmental conditions (p < 0.001). Core temperature (T(CORE)), HR and PRL were significantly elevated only in Hot (p < 0.05). Moderate correlations were found for T(CORE), T(SK), T(B), HS, T(GRAD), HR and CVC with post-exercise PRL (rho = 0.358-0.749). The end-of-exercise <38.0 degrees C T(CORE) responses were not (rho = -0.129, p > 0.05) but the >38.0 degrees C T(CORE) responses were (rho = 0.845, p < 0.001) significantly related to their corresponding PRL responses. The significant relationships between PRL release and T(SK), T(B), HS, T(GRAD), HR and CVC have extended previous research on T(CORE) and PRL release and indicate an association between these thermoregulatory variables, as well as T(CORE), and serotonergic/dopaminergic activity during prolonged exercise.     

Bounds for closed-loop transfer functions of multivariable systems

A multivariable feedback system y(s)=G(s)x(s), x(s) = u(s)- F(s)y(s) is treated where G(s) ≜ (gkl(s)) is the transfer function matrix of a plant and F(s) ≜ diag(f1(s),...,fn(s)) is that of a controller. A new bound for the transfer function hj(s) that relates yj(s) to uj(s) when fj(s)≡ 0 is given. The main result reads |hj(s)- gjj(s)| < aj(s) if |fk(s)^-1+ gkk(s)| > ak(s) for k = 1,... ,n; k≠j. Here, A ≜ diag(a1(s),...,an(s)) is a diagonal matrix which makes A-B a semi-M-matrix where B ≜ (bkl) is given by bkk=0, bkl= |gkl(s)| (k≠l). A similar result is also obtained for the inverse transfer function.     

面向Agent的软件度量研究

本文提出了一套面向Agent软件度量的新指标：知识量、学习能力、反应时间、Agent总数、依赖度、被依赖度、交互数、总交互数、社会理性和智商。并在此基础上开发了一个度量工具原型：度量AgentMA。     

Structural and electron properties of the highest epoxygenated fullerene C(60)O(30), a DFT study

Ab initio Hartree-Fock (HF) and density functional theory (DFT) calculations were carried out to determine the structural and electronic properties of the highest epoxygenated fullerenes C(60)O(30). For comparison, other fullerene oxides C(60)O(29), C(60)O(3), C(60)O(2) and C(60)O were also studied. The highly symmetrical I(h) structure of the parent C(60) is reserved in C(60)O(30) and C(60)O(30) was calculated to be a nonpolar molecule. It was demonstrated that C(60)O(30) should be more stable than other C(60) oxides such as C(60)O(29), C(60)O(3), C(60)O(2) and C(60)O. Compared with C(60), it is less possible for C(60)O(30) to accept or donate electrons from the reduced EAs and enhanced IPs. The IR active modes and harmonic vibrational frequencies of C(60)O(30) were also discussed.     

Fuzzy triangulation signature for detection of change in human emotion from face video image sequence

The present article proposes a geometry-based fuzzy relational technique for capturing gradual change in human emotion over time available from relevant face image sequences. As associated features, we make use of fuzzy membership arising out of five triangle signatures such as - (i) Fuzzy Isosceles Triangle Signature (FIS), (ii) Fuzzy Right Triangle Signature (FRS), (iii) Fuzzy Right Isosceles Triangle Signature (FIRS), (iv) Fuzzy Equilateral Triangle Signature (FES), and (v) Other Fuzzy Triangles Signature (OFS) to achieve the task of appropriate classification of facial transition from neutrality to one among the six expressions viz. anger (AN), disgust (DI), fear (FE), happiness (HA), sadness (SA) and surprise (SU). The effectiveness of the Multilayer Perceptron (MLP) classifier is tested and validated through 10 fold cross-validation method on three benchmark image sequence datasets namely Extended Cohn-Kanade (CK+), M&M Initiative (MMI), and Multimedia Understanding Group (MUG). Experimental outcomes are found to have achieved accuracy to the tune of 98.47%, 93.56%, and 99.25% on CK+, MMI, and MUG respectively vindicating the effectiveness by exhibiting the superiority of our proposed technique in comparison to other state-of-the-art methods in this regard.

     

A global control of polynomial chaotic systems

In this paper, a method of controlling a class of non-linear systems, x = F(x,t) (x element Rn) (or xk+1 = F(xk), (xk element Rn)), where F(x,t) (or F(xk)) is polynomial of degree m on x (or xk), is proposed. It can be proved that there exist solutions, x(t) (or xk), through specified open-loop (Hubler) action and a suitable non-linear closed-loop (feedback) action, which can be entrained to an arbitrary given goal, g(t) (or gk) element Rn, and the controlling basins of entrainment BE(g) (or BE(gk)) are global.     

Thermal comfort and sensation in men wearing a cooling system controlled by skin temperature

OBJECTIVE: The study was done to determine whether thermal comfort (TC), thermal sensation (TS), and subjective factors gauging environmental stress were negatively affected with different cooling methods in men exercising in chemical protective clothing. BACKGROUND: Previous studies have reported that intermittent regional cooling improved the efficacy of cooling as compared with constant cooling (CC), but no studies have addressed whether there is any improvement in thermal comfort. METHODS: Eight male volunteers exercised at moderate work intensity (425 W) in three microclimate cooling tests. The circulating fluid in the cooling garment was provided during exercise to the head (6% body surface area [BSA]), torso (22% BSA), and thighs (44% BSA) and manipulated under three methods: (a) CC, (b) pulsed cooling (PC), and (c) PC activated by mean skin temperature (T(sk)) control (PC(skin)). TC and TS ratings were recorded every 20 min during the 80-min test. RESULTS: TC and TS ratings were not different for PC(skin) and CC; thus the participants perceived PC(skin) as being similar to CC. TS was significantly warmer with PC than with PC(skin) and CC (p < .001). In PC(skin), T(sk) was significantly higher than in PC and CC (p < .001), and PC(skin) was rated as being not as warm as PC according to TS. CONCLUSION: This indicates that the PC(skin) method was perceived as being as cool as CC and cooler than PC. APPLICATION: These findings indicate that the PC(skin) cooling method is an acceptable alternative to CC and PC based on human perceptions.     

Intermittent microclimate cooling during exercise-heat stress in US army chemical protective clothing

The effectiveness of intermittent, microclimate cooling for men who worked in US Army chemical protective clothing (modified mission-oriented protective posture level 3; MOPP 3) was examined. The hypothesis was that intermittent cooling on a 2 min on-off schedule using a liquid cooling garment (LCG) covering 72% of the body surface area would reduce heat strain comparably to constant cooling. Four male subjects completed three experiments at 30 degrees C, 30% relative humidity wearing the LCG under the MOPP 3 during 80 min of treadmill walking at 224 +/- 5 W . m(-2). Water temperature to the LCG was held constant at 21 degrees C. The experiments were; 1) constant cooling (CC); 2) intermittent cooling at 2-min intervals (IC); 3) no cooling (NC). Core temperature increased (1.6 +/- 0.2 degrees C) in NC, which was greater than IC (0.5 +/- 0.2 degrees C) and CC (0.5 +/- 0.3 degrees C) ( p < 0.05). Mean skin temperature was higher during NC (36.1 +/- 0.4 degrees C) than IC (33.7 +/- 0.6 degrees C) and CC (32.6 +/- 0.6 degrees C) and mean skin temperature was higher during IC than CC ( p < 0.05). Mean heart rate during NC (139 +/- 9 b . min(-1)) was greater than IC (110 +/- 10 b . min(-1)) and CC (107 +/- 9 b . min(-1)) ( p < 0.05). Cooling by conduction (K) during NC (94 +/- 4 W . m(-2)) was lower than IC (142 +/- 7 W . m(-2)) and CC (146 +/- 4 W . m(-2)) ( p < 0.05). These findings suggest that IC provided a favourable skin to LCG gradient for heat dissipation by conduction and reduced heat strain comparable to CC during exercise-heat stress in chemical protective clothing.     

一类多项式矩阵方程的洁式解法

本文实际上建议了关于两种多项式矩阵方程X(s)P(s) Y(s)R(s)=F(s)和P(s)X(s) Q(s)Y(s)=G(s)的结式阵解法,式中X(s)和Y(s)为未知多项式阵,其余为适当维数的已知多项式阵。这种解法可以形成计算机算法的基础。它可以用于补偿器的设计。     

NQJ-CIMS的设计与实现

NQJCIMS项目全面改善了企业的“T、Q、C、S、E”五项竞争要素。实现了企业资源计划分系统（ERP）、产品开发分系统（PDS）、制造执行分系统（MES）、质量信息管理分系统（QIS）、办公自动化分系统（OA）等五个分系统的有效集成。以COM／DCOM为软件的集成平台,取得了良好的效果。     

Stabilization of uncertain systems via linear control

This note considers the problem of stabilizing a linear dynamical system (Σ) whose state equation includes a time-varying uncertain parameter vectorq(cdot). Given the dynamicsdot{x}(t)=A(q(t))x(t)+ B(q(t))u(t)and a bounding setQfor the valuesq(t), the objective is to choose a control lawu(t)=p(x(t))guaranteeing uniform asymptotic stability for all admissible variations ofq(cdot). Our results differ from previous work in one fundamental way; that is, we show that when working with linear controllers, it is possible to dispense with all assumptions onB(cdot)which have been made by previous authors (e.g., see [1]-[9]). This elimination of hypotheses onB(cdot)is accomplished roughly as follows: the system(Sigma) {underline {underline Delta}} (A(q), B(q))is shown to be equivalent to another system(Sigma^{+}) {underline {underline Delta}} (A^{+}(q), B^{+})as far as stabilization is concerned. SinceB^{+}is a constant matrix (independent ofq), the desired result is readily obtained.     

Neuromuscular and cardiovascular responses of Royal Marine recruits to load carriage in the field

Cardiovascular and neuromuscular responses of 12 male Royal Marine recruits (age 22 ± 3 years, body mass 80.7 ± 6.8 kg, VO(2)max 52.3 ± 2.7 ml kg(-1) min(-1)) were measured during 19.3 km of load carriage walking at 4.2 km h(-1) and carrying 31.0 kg. Heart rate during load carriage was 145 ± 10 beats·min(-1) (64 ± 5 %HRR) and showed a negative relationship with body mass (r = -0.72, P = 0.009) but no relationship with VO(2)max (ml kg(-1) min(-1); r = -0.40, P = 0.198). Load carriage caused a decrease in vertical jump height (8 ± 9%) and power (5 ± 5%) (P < 0.001). Change in vertical jump power showed a positive relationship with body mass (r(2) = 0.40, P = 0.029) but no relationship to VO(2)max (ml kg(-1) min(-1); r(2) = 0.13, P = 0.257). In conclusion, load carriage caused a reduction in vertical jump performance (i.e. decreased neuromuscular function). Lighter individuals were disadvantaged when carrying absolute loads, as they experienced higher cardiovascular strain and greater decreases in neuromuscular function.     

Analysis of the interaction between the dendritic conductance density and activated area in modulating alpha-motoneuron EPSP: statistical computer model

Five reconstructed alpha-motoneurons (MNs) are simulated under physiological and morphological realistic parameters. We compare the resulting excitatory postsynaptic potential (EPSP) of models, containing voltage-dependent channels on the dendrites, with the EPSP of a passive MN and an active soma and axon model. In our simulations, we apply three different distribution functions of the voltage-dependent channels on the dendrites: a step function (ST) with uniform spatial dispersion; an exponential decay (ED) function, with proximal to the soma high-density location; and an exponential rise (ER) with distally located conductance density. In all cases, the synaptic inputs are located as a gaussian function on the dendrites. Our simulations lead to eight key observations. (1) The presence of the voltage-dependent channels conductance (g(Active)) in the dendrites is vital for obtaining EPSP peak boosting. (2) The mean EPSP peaks of the ST, ER, and ED distributions are similar when the ranges of G (total conductance) are equal. (3) EPSP peak increases monotonically when the magnitude of g(Na_step) (maximal g(Na) at a particular run) is increased. (4) EPSP kinetics parameters were differentially affected; time integral was decreased monotonically with increased g(Na_step), but the rate of rise (the decay time was not analyzed) does not show clear relations. (5) The total G can be elevated by increasing the number of active dendrites; however, only a small active area of the dendritic tree is sufficient to get the maximal boosting. (6) The sometimes large variations in the parameters values for identical G depend on the g(Na_step) and active dendritic area. (7) High g(Na_step) in a few dendrites is more efficient in amplifying the EPSP peak than low g(Na_step) in many dendrites. (8) The EPSP peak is approximately linear with respect to the MNs' R(N) (input resistance).     

Theoretical investigation on carbon-centered tri-s-tetrazine and its 10 derivatives

A novel species, carbon-centered tri-s-tetrazine (C(4)N(9)H(3)), and its 10 derivatives (C(4)N(9)R(3), where R=OH, F, CN, N(3), NH(2), NO(2), N=NH, N(2)H(3), C triple bond CH, and CH=CH(2)) have been studied computationally. Density functional theory (DFT) has been used to study the geometries, electronic structure, harmonic vibrational frequencies, ionization energies of the 11 compounds at the restricted (for neutrals) and the unrestricted (for cations) B3LYP/cc-pVDZ level of theory. Atoms in molecule (AIM) and natural bond orbital (NBO) analyses have been used to obtain the bonding properties. Valence bond (VB) theory is applied to explain the unusual pyramidal structure around the carbon-center and electron arrangements of orbitals. We found: (1) All the species possess novel bonding features and geometrical structures. The atoms on the periphery of each species are sp(2) hybridized. Each of these atoms offers an orbital to form an extensive conjugation system (12)pi(15) (a pi system consisting of 12 centers and 15 electrons). The central carbon atom C13 is sp(3) hybridized, which makes the non-planar molecule shape like a straw-hat. Atom C13 also participates in the conjugated pi system with its sp(3) hybridized orbital, thus forming an extensive (13)pi(16) conjugate pi system covering the whole C(4)N(9) framework. (2) The change of charge on C13 is the largest among all the atoms when the species is ionized and the atomic charges are redistributed. In other words, C13 is the attack center for electrophilic agents. Thus, the species is carbanion-like. (3) All the species have low ionization energies (IEs). The electron ionized mainly comes from C13. They may have wide applications in organic chemistry, in organometallic chemistry and in alkyl lithium chemistry once they are synthesized.     

精甲霜灵的电子结构及圆二色谱性质

采用量子化学密度泛函理论在B3LYP/6-311++G**水平上对精甲霜灵分子几何构型进行优化;在优化的基础上进行圆二色谱究。计算结果表明:(1)C(8)=O(9)与N(1)、C(3)=O(4)与O(5)之间均存在p—π共轭,N原子上另外2个取代基分别位于苯环上下方为最稳定构型。(2)VCD谱中,C(10)—H沿C(8)—C(10)—O(11)平面的摇摆振动在1020cm-1处存在正性康登效应;垂直于该平面的摇摆振动在1273cm-1处出现负性康登效应。C(2)原子上的C—H摇摆振动在的1334cm-1处存在强的康登效应。C(3)=O(4)在的1788cm-1处出现较强的吸收峰;C(8)=O(9)由于与手性中心的间隔一个N原子,其在VCD谱中未出现康登效应。(3)甲醇溶液中的理论ECD谱,228nm处存在正性康登效应,与实验值符合较好;同时,理论计算还预测标题化合物在201nm处存在负性康登效应。     

粗糙集中不同核的比较研究

为研究基于HU差别矩阵属性约简的核(HCore(C))、信息熵属性约简的核(ECore(C))、分布属性约简的核(FCore (C))、最大分布属性约简的核( MCore (C))、近似属性约简的核(ACore (C))和正区域属性约简的核(PCore (C))之间的关系,本文给出了上述各种核的简化差别矩阵计算方法,并用上述各种核的计算方法证明了如下结论:在不一致决策表中,HCore( C)(∩)ECore( C):FCore( C) (∩)ACore( C)) (∩)PCore( C);用实例说明了MCore(C))和ACore(C))之间没有关系,MCore (C))和PCore (C))之间没有关系;而在一致决策表中,各种不同核是相互等价的.     

Studies of tricyclic piperazine/piperidine furnished molecules as novel integrin αvβ3/αIIbβ3 dual antagonists using 3D-QSAR and molecular docking

The development of injectable integrin α(v)β(3)/α(IIb)β(3) dual antagonists attracts much attention of research for treating of acute ischemic diseases in recent years. In this work, based on a dataset composed of 102 tricyclic piperazine/piperidine furnished dual α(v)β(3) and α(IIb)β(3) antagonists, a variety of in silico modeling approaches including the comparative molecular field analysis (CoMFA), comparative similarity indices analysis (CoMSIA), and molecular docking were applied to reveal the requisite 3D structural features impacting the biological activities. Our statistical results show that the ligand-based 3D-QSAR models for both the α(v)β(3) and α(IIb)β(3) studies exhibited satisfactory internal and external predictability, i.e., for the CoMFA models, results of Q(2)=0.48, R(ncv)(2)=0.87, R(pred)(2)=0.71 for α(v)β(3) and Q(2)=0.50, R(ncv)(2)=0.85, R(pred)(2)=0.72 for α(IIb)β(3) analysis were obtained, and for the CoMSIA ones, the outcomes of Q(2)=0.55, R(ncv)(2)=0.90, R(pred)(2)=0.72 for α(v)β(3) and Q(2)=0.52, R(ncv)(2)=0.88, R(pred)(2)=0.74 for α(IIb)β(3) were achieved respectively. In addition, through a comparison between 3D-QSAR contour maps and docking results, it is revealed that that the most crucial interactions occurring between the tricyclic piperazine/piperidine derivatives and α(v)β(3)/α(IIb)β(3) receptor ligand binding pocket are H-bonding, and the key amino acids impacting the interactions are Arg214, Asn215, Ser123, and Lys253 for α(v)β(3), but Arg214, Asn215, Ser123 and Tyr190 for α(IIb)β(3) receptors, respectively. Halogen-containing groups at position 15 and 16, benzene sulfonamide substituent at position 23, and the replacement of piperazine with 4-aminopiperidine of ring B may increase the α(v)β(3)/α(IIb)β(3) antagonistic activity. The potencies for antagonists to inhibit isolated α(v)β(3) and α(IIb)β(3) are linear correlated, indicating that similar interaction mechanisms may exist for the series of molecules. To our best knowledge this is the first report on 3D-QSAR modeling of these dual α(v)β(3)/α(IIb)β(3) antagonists. The results obtained should provide information for better understanding of the mechanism of antagonism and thus be helpful in design of novel potent dual α(v)β(3)/α(IIb)β(3) antagonists.     

Vague故障诊断方法在振动故障诊断中的应用

提出模糊数据[hij]化成Vague数据[hij]的转化公式：[Ki(hj)=hij=[tij,1-fij]=(hij)2,(hij)1/2],以及Vague集[H]和[G]之间的相似度量公式：[Mm(H,G)=1ni=1n3-f(m)hi-f(m)gi-c(m)hi-c(m)gi-d(m)hi-d(m)gi3+f(m)hi-f(m)gi+c(m)hi-c(m)gi+d(m)hi-d(m)gi]。应用Vague故障诊断方法,进行汽轮发电机组的振动故障诊断,其效果是理想的。