Gas chromatography of halogens

Summary The semi-empirical theory on the retention volume in gas chromatography recently developed by some experiments, was found to require partial correction. It was newly refined and summarized. Overall experimental checking was performed by the use of Cl₂, Br₂, and I₂.

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Gas-Chromatographie von Halogenen

Zusammenfassung Die halbempirische Theorie über das Retentionsvolumen in der Gas-Chromatographie, die kürzlich an Hand einiger Versuche entwickelt wurde, erforderte eine teilweise Korrektur. Sie wurde verbessert und zusammenfassend dargestellt. Kontrollversuche wurden mit Hilfe von Chlor, Brom und Jod durchgeführt.

     

Gas chromatography of some prostaglandins

Summary The synthetic prostaglandin F_2α (PG_2α), used as an ovulation regulator, and abortion inducer, is contaminated with its Δ5-trans isomer. The ratio of the isomers was measured by capillary GC. The prostaglandin I₂ (PGI₂), a blood platelet aggregation inhibitor, easily decomposes to 6-ketoprostaglandin F_1α (6-keto PG_1α). Their ratio was measured by packed column GC. An unexpected, instantaneous methanol cleavage was observed during the GC analysis of the methyl ketal derivative of 6-keto PG_1α, forming a mixture of PGI₂ and Δ6-prostaglandin I₁ (Δ6-PGI₁). Presented at the 15th International Symposium on Chromatography, Nürnberg, October 1984