游离股前外侧皮瓣修复头颈部缺损术后供区功能调查

目的:评价股前外侧皮瓣(ALT)修复头颈部缺损术后供区的功能,为选择ALT皮瓣修复头颈部软组织缺损提供理论依据.方法:应用问卷调查的方法随访2004-11-2008-05于中山大学肿瘤防治中心应用ALT皮瓣修复头颈部缺损的14例患者,评价手术对供区外观满意度、感觉及运动功能的影响.结果:所有患者供区伤口均能一期拉拢缝合...     

股前外侧皮瓣在外阴肿瘤术后的修复应用

目的：评价股前外侧皮瓣在外阴肿瘤术后缺损修复中的应用价值。方法：应用带旋股外侧动脉降支和股前外侧皮神经为蒂的股前外侧皮瓣一期修复外阴肿瘤术后缺损１０例,皮瓣大小为１０ｃｍ×１４ｃｍ～１４ｃｍ×２０ｃｍ。结果：１０例皮瓣全部成活,随访２～１２个月,外观满意,皮瓣感觉功能存在,局部肿瘤无复发。结论：股前外侧皮瓣血管蒂长,血管口径大,供瓣区隐蔽。带感觉神经的股前外侧皮瓣是一种适合外阴肿瘤术后缺损修复的理想皮瓣。     

游离股前外侧皮瓣在皮肤和软组织肿瘤切除术后重建中的应用

摘 要：［目的］评价运用游离股前外侧皮瓣治疗躯干及四肢皮肤和软组织肿瘤切除术后缺损的疗效。［方法］ 自2011年5月至2016年10月浙江省肿瘤医院骨与软组织肿瘤外科收治了27例运用游离股前外侧皮瓣修复皮肤和软组织肿瘤手术引起的组织缺损的病例。［结果］ 股前外侧皮瓣面积为5cm×6cm~15cm×21cm。77.8%（21/27）患者愈合佳,无明显坏死,与周围皮肤无明显高度差。18.5%（5/27）患者出现小范围边缘坏死（坏死面积10%~30%）,予以积极换药后2月左右愈合。3.7%(1/27)患者出现静脉性血管危险,术后第一天予以急诊手术探查,术后出现皮瓣边缘小范围坏死（面积约15%）,予以积极换药后2月左右愈合。在随访期内未见局部肿瘤复发及转移。［结论］ 股前外侧皮瓣移植在躯干及四肢软组织和皮肤肿瘤的术后重建中有着不可替代的作用及巨大的潜力。     

应用折叠型游离股前外侧皮瓣修复面颊贯通性缺损12例

目的：探讨折叠型游离股前外侧皮瓣在修复面颊贯通性缺损中的临床应用效果。方法：2010年1月至2014年10月,在中山大学附属肿瘤防治中心应用折叠型游离股前外侧皮瓣修复12例面颊贯通性缺损的患者。分析获取游离股前外侧皮瓣的手术过程、血管吻合技巧以及皮瓣存活率。结果：11例皮瓣存活,1例因术后静脉血栓形成而坏死。在12例患者中,游离股前外侧皮瓣的供区均一期缝合,供区的线性瘢痕隐蔽性好,且供区大腿的功能不受影响。结论：游离股前外侧皮瓣具有良好的可塑性,折叠后可同时修复面颊贯通性缺损的内侧及外侧,具有供区并发症少、外观易接受及患者满意率高的优点。     

薄型股前外侧皮瓣修复中晚期舌癌术后组织缺损的临床疗效

摘 要：［目的］ 探讨薄型股前外侧皮瓣修复中晚期舌癌术后组织缺损的临床疗效。［方法］ 对85例中晚期舌癌术后组织缺损欲进行修复患者作为研究对象,按照修复皮瓣不同将其分为观察组与对照组,观察组43例,采用薄型股前外侧皮瓣进行修复,对照组42例,采用前臂桡侧皮瓣进行修复。对两组患者皮瓣存活率、术后并发症发生情况、舌功能恢复情况以及患者生活质量恢复情况进行比较。［结果］ 观察组患者皮瓣存活率为90.70%（39/43）,对照组为78.57%（33/42）,两组比较差异无统计学意义（P>0.05）。两组患者受区并发症发生率无显著差异（P>0.05）,而观察组患者供区并发症发生率明显低于对照组,差异有统计学意义（P<0.05）。两组患者在舌功能恢复情况方面比较差异均无统计学意义（P>0.05）。观察组患者术后生活质量恢复总有效率为83.72%,对照组为52.38%,观察组明显高于对照组,差异有统计学意义,且改善率有明显差别（P<0.05）。［结论］ 薄型股前外侧皮瓣修复中晚期舌癌术后组织缺损具有良好的临床疗效及安全性,有利于患者生活质量恢复,值得临床推广应用。     

CTA并三维重建技术在指导游离股前外侧皮瓣制备中的应用

目的:应用CTA并三维重建技术对穿支进行定位和选择,设计皮瓣及手术方案,以期最合理制备游离股前外侧皮瓣.方法:2012年6月至2014年12月间,60例头颈肿瘤切除术后拟行游离股前外侧皮瓣修复的患者,随机分配成A、B组.A组术前双侧下肢CTA血管成像并三维重建,指导设计皮瓣;B组术前以彩色多普勒定位穿支.比较两组准确率、取瓣成功率、平均花费时间、供瓣区多余创伤等方面的差别.结果:A组中2例术前血管成像不满意,未实施计划.其余28例手术均按计划取瓣成功.B组术前1例未发现穿支,其余29例均探测到穿支,但术中发现穿支定位有一定误差.A组在取瓣成功率、取瓣时间优于B组,供瓣区多余创伤小于B组.结论:应用CTA并三维重建技术,术前对股前外侧皮瓣穿支进行选择和定位,可以提高制备皮瓣的成功率,节省手术时间,并最大限度减少供区创伤,尤其设计多瓣进行复杂缺损的情况下具有明显优势,值得推广.     

薄型股前外侧皮瓣修复舌癌术后软组织缺损的疗效分析

目的探讨薄型股前外侧皮瓣修复舌癌术后软组织缺损的效果。方法选取90例舌癌术后软组织缺损部软组织缺损患者,根据修复方法的不同分为薄型股前外侧皮瓣、前臂桡侧游离皮瓣、小腿内侧游离皮瓣各30例。皮瓣切取平均面积为(1.2×1.5)cm^2^1.8×2.5cm^2,比较3种手术方式的有效率及舌癌术后软组织缺损修复的满意度。结果 3种手术方式有效率间没有明显差异,无统计学意义(P=0.075);薄型股前外侧皮瓣修复舌癌术后软组织缺损满意度明显优于其他方法,具有统计学意义(P=0.069)。结论对舌癌术后软组织缺损部软组织缺损患者采用不同部位的游离皮瓣修复均取得了良好的修复效果,其中薄型股前外侧皮瓣修复满意度明显高于其他方法,提高患者的康复效果。     

股前外侧肌皮瓣在舌根缺损修复中的应用

目的 探讨股前外侧肌皮瓣修复舌根缺损的效果。方法 应用股前外侧肌皮瓣修复舌根鳞癌术后缺损一例，术后随访。结果 术后创口一期愈合，一年后随访舌体外形良好，吞咽及语言功能满意。结论 该肌皮瓣动脉血管蒂恒定、皮下脂肪较厚，适于修复舌根软组织缺损；皮瓣血管口径较大．易于吻合；供区隐蔽，取瓣方便。     

股前外侧皮瓣在口腔颌面部修复重建中的临床应用

目的 探讨修复各类口腔颌面部缺损时应用游离股前外侧皮瓣的可能性和实用性。方法 2011年3月至2018年12月共开展股前外侧皮瓣移植术63例,皮瓣最小面积4×6 cm,最大面积7×22 cm;修复缺损部位有舌部26例,颊部15例,口底区8例,下颌6例,口咽部3例,上颌2例,软腭2例,面部大面积缺损1例。其中,肌皮瓣55例,分叶皮瓣8例。术中一期削薄48例,其中粗修46例,精修2例。结果 游离股前外侧皮瓣的临床成活率为98.4％(62／63)。术后血管危象2例,其中1例抢救成功,失败1例,组织瓣坏死。削薄皮瓣均无坏死,无大腿皮瓣供区感染。术后患者均获得可接受的面部外形以及咀嚼、吞咽和语言功能。结论 游离股前外侧皮瓣可以很好的修复口腔颌面部各种复杂的缺损。     

前臂皮瓣与股前外侧皮瓣修复口腔癌术后缺损的临床研究

目的 比较前臂皮瓣与股前外侧皮瓣在口腔癌术后缺损中的修复效果。方法 选取84例口腔癌术后缺损并行游离皮瓣修复术的患者为研究对象,按随机数字表法分为2组,各42例。对照组行前壁皮瓣修复,观察组行股前外侧皮瓣修复。观察至术后3个月,对比2组皮瓣成活率、手术情况、口腔功能、并发症。结果 2组皮瓣成活率、皮瓣制作时间、住院时间、口腔开合、吞咽、咀嚼、语言功能评分相比,差异无统计学意义(P>0.05);观察组手术时间长于对照组,皮瓣面积大于对照组,并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论 前臂皮瓣与股前外侧皮瓣均具有良好的皮瓣成活率,可有效改善口腔癌术后缺损患者的口腔功能,且治疗效果相当。前臂皮瓣修复手术时间短,股前外侧皮瓣修复术后并发症少,临床应根据患者具体情况选取适当的皮瓣修复。     

腹直肌肌皮瓣修复肿瘤相关腹股沟区软组织缺损临床价值的探讨

目的:探讨横行腹直肌肌皮瓣修复与肿瘤相关腹股沟区软组织缺损的临床价值。方法:2000-01-2009-01应用本法共修复腹股沟区软组织缺损12例,其中恶性纤维组织细胞瘤4例,滑膜肉瘤2例,鳞状细胞癌2例,恶性黑色素瘤转移2例,纤维瘤病1例,横纹肌肉瘤术后1例;原发3例,复发7例,放疗后切口溃烂2例(滑膜肉瘤、横纹肌肉瘤术后各1例);滑膜肉瘤术后放疗后复发1例。结果:围手术期腹直肌肌皮瓣移植,11例全部成活,1例部分坏死;11例平均随访15个月,1例失访;局部复发1例,肺、脑转移死亡3例,余8例均生存,供区无并发症出现。结论:腹直肌肌皮瓣修复腹股沟软组织缺损具有愈合快、抗感染力强、供区隐蔽以及手术操作方便等优点,可实行双组手术,宜于修复较大腹股沟区软组织缺损。     

A simplified technique of free flap pedicle transfer for reconstruction of defects following head and neck cancer ablation

Free flaps are being widely used for reconstruction of defects following head and neck cancer ablation. The pedicle of the flap is usually tunneled into the neck wound for anastomosis to the neck vessels. This transfer of the pedicle can be technically difficult to execute and associated with difficulties of torsion and kinking. No effective method has been so far reported to make this procedure easy and safe. A very easy and effective method for the pedicle transfer is described in this report, which has been practiced successfully in our head and neck service in more than 175 free flaps.     

头颈部肿瘤修复皮瓣对放疗的耐受性

目的:探讨吻合血管的游离皮瓣组织对局部放疗的耐受性及安全性。方法:选取我院2015年至2018年收治的经皮瓣修补术头颈恶性肿瘤患者11例，采用适形调强放疗（IMRT）或旋转调强放疗（VAMT）常规分割剂量进行放疗，放疗期间及放疗结束后通过复查喉镜、颈部增强CT或MR，观察移植皮瓣急性放射性反应情况。结果:放疗过程中皮瓣组织表现为色素沉着、干性脱皮，且伴有不同程度的充血水肿，与周围放疗野内组织床相仿，反应程度随着放疗剂量的增加而加重。放疗结束后11例患者移植皮瓣无1例出现皮瓣坏死。放疗3个月后复查喉镜、颈部增强CT或MR，咽喉腔内颈阔肌皮瓣愈合良好，无出血坏死，2例患者皮瓣区充血水肿消退。胸大肌皮瓣修复的颈部淋巴结转移患者中，皮瓣区色素沉着有所缓解，术痕区愈合良好，无干性脱皮。结论:颈阔肌皮瓣、胸大肌皮瓣对于临床常规剂量（<70 Gy）术后放疗具有良好的耐受性，相对安全可靠。     

Recent advances in head and neck surgical oncology

In recent years, the field of head and neck oncology has witnessed a remarkable transformation with unprecedented advances that have revolutionized the management of complex tumors in this region. As an intricate subspecialty within oncology, head and neck surgical procedures demand detailed knowledge of the complex anatomy meticulous precision in surgical technique, and expertise to preserve vital functions while ensuring optimal oncological outcomes. With the relentless pursuit of improved patient outcomes, the integration of innovative technologies has significantly enhanced the surgical armamentarium. Robotics, endoscopic platforms, and image-guided navigation have revolutionized the surgical approach, enabling precise tumor resection and sparing healthy tissues. Furthermore, the application of advanced imaging modalities and molecular biomarker profiling has opened new avenues for personalized treatment strategies. From targeted therapies and immunotherapies to adaptive radiation techniques, clinicians are now equipped with an array of tailored options, ushering in a new era of personalized care for patients with head and neck malignancies. This article delves into the unfolding narratives of clinical triumphs, exploring the transformative potential of emerging therapies and the collaborative efforts propelling head and neck surgical oncology toward a future of hope and healing.     

Complications of free flap transfers for head and neck reconstruction following cancer resection

The reported success rate of microvascular free flap reconstruction ranges between 95% and 97%. However when complications occur, they must be identified early and managed efficiently because there is a narrow window of opportunity to salvage potential flap failure. While technical advances in instrumentation and magnification have improved overall success rates, the rare complication may prove devastating for the patient, his/her hospital stay, and the optimum rehabilitation. Complications of microvascular free tissue transfer may occur at the recipient site or at the donor site. Complications occurring at the recipient site are largely a result of vessel thrombosis while complications occurring at the donor site may result from many causes, ranging from infection to those related to the harvesting of the flap. Irrespective of the site of the complication, it is essential that complications be recognized and addressed early in their course to prevent or minimize devastating consequences.     

Chest radiograph appearances after head and neck flap reconstructive surgery

The chest radiographs of 17 patients who had undergone pectoralis major myocutaneous flap (PMMF) reconstruction for head and neck cancers were reviewed. Surgical procedure correlated well with radiographic findings, which consisted of the following signs: abnormal axillary and supraclavicular folds, replacement of normal vertical neck fold by an oblique fold, soft tissue mass and loss of facial plane at base of the neck. Unilateral radiolucent hemithorax was present in 41% of cases. In females, loss of breast shadow simulating the post-mastectomy appearance was present.     

Prognostic factors in head and neck soft tissue sarcomas: Analysis of 128 cases

Soft tissue sarcomas make up a heterogenous group of rate malignant tumors originating from mesodermal tissues. Although there have been several improvements in diagnostic methods, staging, and treatment over the past few years, the prognosis of head and neck sarcomas remains worse than those sited at the trunk or extremities. The purpose of this retrospective study was to report the survival results of 128 consecutive patients with soft tissue sarcomas of the head and neck treated from 1953 to 1985. Of the 93 patients submitted to surgical resection, the procedure was considered radical in 67 patients. Of the operated gruop, 46 patients (49.5%) developed recurrence of disease. Thirty-two patients underwent further treatment (surgery, radiotherapy, or chemotherapy), and 14 patients were salvaged, giving the ultimate result of 65.6% disease control rate in the operated group. The univariate survival analysis showed no statistical difference (P > 0.05) according to age, race, sex, and site or histologic type of the tumor. Radicality of surgery was an important prognostic factor affecting survival (P = 0.0014 for disease-free interval and P = 0.0183 for overall survival). The multivariate analysis showed that the radicality of surgery and tumor histology were independent prognostic factors affecting recurrence. The same variables and age group were related to the risk of death. Every effort must be made to make an early diagnosis and a radical surgical resection of these tumors must be tried (except for embryonal rhabdomyosarcoma), because it offers the best chance for cure. © 1994 Wiley-Liss, Inc.     

带蒂胸大肌肌皮瓣移植在头颈癌放疗后手术中的运用

目的：探讨头颈癌放疗后因肿瘤复发进行挽救性手术，带蒂胸大肌肌皮瓣修复手术切除后软组织缺损的可行性和价值。方法：7例头颈部恶性肿瘤进行了根治性放疗后局部复发或颈淋巴结转移，通过手术切除病灶，颈淋巴结清扫，同侧带蒂胸大肌肌皮瓣移植修复软组织缺损创面。结果：7例移植的带蒂胸大肌肌皮瓣全部成活，有2例出现切口裂开，愈合困难。结论：在头颈癌放疗后手术中，带蒂胸大肌肌皮瓣移植是修复手术切除后软组织缺损的有效方法。