原发性三叉神经痛患者射频热凝术后脑干听觉诱发电位的研究

目的探讨脑干听觉诱发电位（brainstem auditory evoked potentials,BAEP）V波在原发性三叉神经痛患者射频热凝术前后的变化意义。方法对29例原发性三叉神经痛患者行射频热凝术前后BAEP的V波值进行测定,并行统计学分析。结果射频治疗前后,患侧V波潜伏期、Ⅰ-Ⅴ波间期、双侧V波潜伏期差、双侧Ⅰ-Ⅴ波间期有统计学差异（P〈0.05）.结论BAEP的V波值在临床上可以作为原发性三叉神经痛射频治疗疗效评价的客观指标之一。     

脑干听觉诱发电位诊断脑瘫患儿听觉损伤效果观察

目的:观察脑干听觉诱发电位(BAEP)诊断脑瘫患儿听觉损伤的效果。方法:选择确诊脑瘫患儿120例为观察组,选择正常儿童40例为对照组,均进行BAEP检查,并比较各组间听觉诱发电位的差异。结果:观察组BAEP异常36例,异常率30.0%;观察组各波潜伏期及波间距均较对照组显著或非常显著延长(P<0.05,P<0.01)。结论:脑瘫患儿合并听神经传导通路损伤发生率较高,BAEP应作为其常规检查之一。     

高压氧对脑外伤后综合征患者脑干听觉诱发电位与循环动力学的影响

目的探讨高压氧（HBO）综合疗法对脑外伤后综合征（post traumatic brain syndrome，PTBS）患者的疗效，评价脑干听觉诱发电位（brainstem auditory evoked potential，BAEP）和脑血管功能检测（cerebral vascular function determination，CVD）与临床症状的关系。方法43例PTBS患者分为两组：HBO治疗＋常规治疗组（HBO组，n=22）和常规治疗组（n=21）。治疗前后对BAEP、CVD进行检测，并与性别、年龄相匹配的健康者对比。结果BAEP主要异常为Ⅰ、Ⅲ、Ⅴ波潜伏期（PL）延长或Ⅰ-Ⅲ、Ⅲ-Ⅴ、Ⅰ—Ⅴ峰间潜伏期（IPL）延长，异常率为59．5％，HBO组治疗后与治疗前相比，差异有统计学意义（P〈0．05）；常规治疗组治疗后与治疗前相比，差异无统计学意义（P〉0．05）。CVD主要异常为血管外周阻力（R）和动态阻力（DR）升高，HBO组治疗后与治疗前相比，差异有统计学意义（P〈0．01）；与常规治疗组相比，差异也有统计学意义（P〈0．05）。结论HBO综合疗法对PTBS患者的临床恢复有积极的作用，BAEP和CVD的检测结果可为临床诊断提供一定的依据。     

神经节苷脂治疗急性脑外伤的神经电生理研究

目的 探讨单唾液酸四己糖神经节苷脂（ＧＭ１）对急笥脑外伤的治疗作用。方法 对２０例中,重型脑外伤患者缓慢静脉推注ＧＭ１ １００ｍｇ／ｄ,每次用药前,用药后１,３小时监测正中神经短潜伏期体感诱发电位（ＳＬＳＥＰ）和脑干听觉诱发电位（ＢＡＥＰ）,经统计分析用ＧＭ１前后主要峰间潜伏期（ＩＰＬ）的变化情况。     

BAEP对脑室出血的预后分析

目的：探讨脑室出血BAEP动态变化规律。方法：采用NEB5l00型脑诱发电位仪记录37例脑室出血患者的BAEP。结果：(1)37例经BAEP检测后，正常5例；(2)峰潜伏期(PL)及峰间期(IPL)延长；(3)波幅降低，V／I波幅比值降低；(4)波形改变，各波不易辨认，重复性差；(5)波缺失。结论：BAEP正常或逐渐恢复正常，临床预后好；BAEP改变进行性加重者，预后差。     

红藻酸致大鼠癫痫模型短潜伏期体感诱发电位分析

目的：了解癫痫发作时大脑神经元的功能状态。方法：２０只红藻酸致痫大鼠于癫痫发作前、急性发作期、慢性发作期经正中神经刺激对短潜伏期体感诱发电位（ＳＬＳＥＰ）进行测定。结果：大鼠ＳＬＳＥＰ波形为一小的Ｎ１波后接一大的Ｐ１波；癫痫急性发作期改变为Ｎ１、Ｐ１波的ＰＬ延长，波幅降低，有３例波形缺失；慢性发作期仅Ｐ１波的Ｐ１较前缩短。结论：癫痫急性发作期Ｎ１、Ｐ１波的改变与兴奋性氨基酸的神经元毒性作用及继发性缺血、缺氧致神经元损伤有关。慢性发作期Ｐ１波缩短的机理有待进一步研究。     

30d-6°头低位卧床恢复期视觉诱发电位的变化

目的 观察健康人在30 d头低位外床实验结束后,视觉诱发电位恢复的情况.方法 选取8名健康志愿者,-6°头低位卧床模拟失重状态下30 d,记录实验开始前,结束后当日及第2天、第3天双眼在不同空间频率下的视觉诱发电位,标记P100波.结果 在不同空间频率下,视觉诱发电的P100波的潜伏期及波幅在实验开始前与结束前后均无显...     

持续性＋Gz作用对清醒家兔脑干听觉诱发电位的影响

本实验分析测量了不同G 值怍用条件下清醒家兔的脑干听觉诱发电位(BAEP),结果发现较低值的+Gz 作用对BAEP 潜伏期无明显影响5、6、7G 作用可使BAEP 1波峰潜期显著延长,而1～5波峰间潜期相对稳定。+Gz 作用对BAEP 各波幅值和频域特性有一定程度的影响。其影响机制可能与+Gz 作用引起的头水平血流减少和异常外周传入增加有关。实验结果可为超重条件下的工效学研究提供有益的参考。     

重型脑损伤后Terson综合征

目的：研究重型脑损伤（SBI）后Terson综合征（TS）发生的相关因素和临床特点。方法：监测161例脑损伤病人的颅内压（ICP）、眼内压（IOP）、脑灌注压（CPP）、视觉诱发电位（VEP）和视力,分析它们与SBI后TS的关系。结果：SBI后TS的发生率显著高于对照组;TS的发生与急性ICP和IOP增高密相关,发生TS病人的ICP和IOP显著高于对照组;急性IOP增高与急性ICP增高呈正相关,ICP曲线上出现A波者大多发生TS。结论：SBI后IOP和ICP明显增高的病人易发生TS;有效控制ICP和IOP,防止ICP曲线上A波出现,有助于减少TS的发生和改善病人预后。     

早期帕金森病患者神经电生理检测探讨

目的探讨早期帕金森病患者是否存在神经电生理检测方面的异常。方法选取50例Hoehn-Yahr分级≤2.5级PD患者（PD组）和55例年龄、性别与之相匹配的健康体检者（对照组）进行神经电生理检测。结果PD组与对照组比较,PD组下肢胫神经潜伏期延长、感觉神经传导速度减慢、波幅降低（P<0.05）,四肢SSR上、下肢波幅明显下降（P<0.05）;同时将早期PD患者的患侧与健侧SSR进行比较,患侧上肢和下肢的SSR潜伏期明显延长,波幅明显降低（P<0.05）。视觉诱发电位与对照组相比各波潜伏期均有延长,差异有统计学意义（P<0.05）,而P100波幅未见明显差异。PD组与对照组脑干听觉诱发电位比较,各波峰潜伏期及峰间潜伏期差异均无统计学意义（P>0.05）。睡眠监测PD组也表现出快速眼动睡眠期行为障碍（RBD）例数显著高于对照组,PSG监测REM期肌肉弛缓和下颌位相性肌电活动密度两组也存在差异（P<0.05）。结论神经电生理监测可为PD早期诊断提供一定依据,且可能对评估PD病情严重程度也具有重要价值。     

Visual evoked and brain stem auditory evoked potentials in divers.

Visual evoked potentials (VEP) were examined in 14 divers during dives to 360 metres of seawater (msw). All latencies increased significantly with depth. VEP and brain stem auditory evoked potentials (BAEP) were similarly examined in 18 divers before and after these dives. N75 was significantly increased after compared to before the dive, while there was no significant difference in the P100 and N145 latencies. BAEP I-V latency was significantly decreased after the dives. VEP and BAEP were examined in 156 divers and 99 controls. There was no significant difference in VEP. BAEP I-III interpeak latency was significantly increased for the divers, but with no significant changes in I-V and III-V latencies. VEP and BAEP were examined in 26 divers after treatment for neurological decompression sickness. There was no significant difference compared to the control group. The conclusions are that VEP and BAEP change transitorily with influence of hyperbaric pressure, but do not measure major permanent disturbances in the divers' visual and auditory pathways.     

Influence of magnetic resonance imaging on evoked potentials and nerve conduction velocities in humans

The authors investigated the influence of a 1.0-T magnetic field of a magnetic resonance (MR) imaging device, as well as the possible effects of the changing magnetic field and the RF field, on somatosensory, visual, and auditory evoked potentials and on peripheral nerve conduction velocities. The neural potentials outside and inside the static magnetic field were recorded before and after MR imaging. The measured latencies before and after MR imaging were within the normal range for healthy volunteers. The magnetic field did not significantly alter central or peripheral conduction velocities.     

鼻咽癌放疗后继发性鼻窦炎影响因素的分析

目的：分析鼻咽癌患者放疗后发生鼻窦炎的影响因素。方法：采用Logistic回归方法回顾性分析鼻咽癌患者放疗后发生鼻窦炎的影响因素。结果：153例鼻咽癌放疗后患者中有66例发生了鼻窦炎。T分期较高、鼻腔有侵犯的患者鼻窦炎发生率较高（P=0.003；OR=1.983和P=0.024；OR=2.353）。放疗中及放疗后有进行鼻咽冲洗处理的患者鼻窦炎发生率较低（P=0.000；OR=0.183）。结论：对于鼻咽癌患者，特别是T分期较高、有鼻腔侵犯的患者，加强放疗中及放疗后鼻咽冲洗可减少鼻窦炎的发生，改善患者的生存质量。     

20—40岁颈椎病患者的短潜伏期体感诱发电位

40例20—40岁颈椎病患者的体感诱发电位检测表明:检测的阳性率为77.5%;检测的阳性率与检测方法有关;体感诱发电位的结果在一定程度上反映了病理特点、病情程度以及治疗效果;在根性症状的颈椎病患者中,体感诱发电位的敏感性高于浅感觉的物理检测法,也高于X线平片。     

高压氧对脑梗死患者脑电图和诱发电位的影响

目的研究高压氧（HBO）对急性脑梗死患者脑电图（EEG）和脑干听觉诱发电位（BAEP）的影响。方法94例急性脑梗死患者分为HBO治疗组和对照组各47例，疗程2周；治疗前后检查EEG和BAEP等。结果HBO组总有效率96．3％，对照组66．0％（P〈0．01）；HBO治疗后EEG和BAEP均比治疗前明显改善（P〈0．05，P〈0．01）；对照组虽亦改善，但不如HBO组明显。结论HBO治疗可以有效改善急性脑梗死患者脑功能。     

Human brainstem auditory evoked potentials (BAEP) before and after MR examinations

Recently significant changes of human brainstem auditory evoked potentials (BAEP) after exposure to static magnetic fields were reported (L. von Klitzing, Clin. Physiol. Meas. 7(2), 157 (1986); L. Stojan, D. Sperber, and K. Dransfeld, Naturwissenschaften 75, 622 (1988]. We recorded BAEPs of 11 subjects before and after a routine MRI examination at 1.5 T. In addition the BAEP of a healthy volunteer was measured in five different static magnetic fields (0-2.0 T). Our results indicate that routine MRI investigations do not significantly alter the interpeak latencies of the BAEPs.     

The effect of iohexol on brainstem auditory evoked potentials

Summary A prospective study was made to evaluate the effect of intrathecal injection of iohexol on brainstem auditory evoked potentials (BAEP) following myeloradiculography, in order to assess its neurotoxicity. Thirty patients who received contrast medium via the lumbar route for myeloradiculography (cervical level=25 patients, lumbar level=5 patients) had BAEP examinations before, 2 h and 24 h after myelography. No statistically significant prolongation of absolute and interpeak latencies was found between premyelographic and postmyelographic records. Low incidence (20%) of insignificant clinical adverse effect following myelography was also noted in the same group of patient.     

高压氧治疗对中重型颅脑损伤患者脑干和体感诱发电位的影响及疗效分析

目的 观察高压氧(hyperbaric oxygen,HBO)治疗对外伤性中重型颅脑损伤患者脑干听觉诱发电位(bralnstem auditory evoked potential,BAEP)、体感诱发电位(somatic evoked potential,SEP)的影响及其治疗效果.方法 134例外伤性中重型颅脑损伤患者分为对照组67例和HBO治疗组67例.对照组采用必要的神经外科处理及常规药物治疗;HBO组在对照组治疗的基础上,病情稳定后加用3个疗程的HBO治疗.治疗前后行BAEP、SEP检查及格拉斯哥昏迷评分(GCS),伤后6个月随访行格拉斯哥预后评分(GOS).结果 治疗前2组患者BAEP、SEP异常率及GCS评分差异无统计学意义(P>0.05);治疗后对照组BAEP明显改善(P<0.05),SEP改善更为显著(P<0.01),GCS评分明显升高(P<0.05),HBO组BAEP、SEP改善均有统计学意义(P<0.01),GCS评分提高有统计学意义(P<0.01);治疗后HBO组BAEP、SEP异常率与对照组比较差异有统计学意义(P<0.01),GCS评分与对照组比较差异有统计学意义(P<0.05);伤后6个月GOS评分显示HBO组预后良好患者较对照组明显增多(P<0.01),死亡率则明显降低(P<0.05).结论 HBO可明显改善中重型颅脑损伤患者BAEP及SEP的异常情况,提高临床疗效.     

高压氧治疗对中重型颅脑损伤患者脑干和体感诱发电位的影响及疗效分析

目的 观察高压氧(hyperbaric oxygen,HBO)治疗对外伤性中重型颅脑损伤患者脑干听觉诱发电位(bralnstem auditory evoked potential,BAEP)、体感诱发电位(somatic evoked potential,SEP)的影响及其治疗效果.方法 134例外伤性中重型颅脑损伤患者分为对照组67例和HBO治疗组67例.对照组采用必要的神经外科处理及常规药物治疗;HBO组在对照组治疗的基础上,病情稳定后加用3个疗程的HBO治疗.治疗前后行BAEP、SEP检查及格拉斯哥昏迷评分(GCS),伤后6个月随访行格拉斯哥预后评分(GOS).结果 治疗前2组患者BAEP、SEP异常率及GCS评分差异无统计学意义(P>0.05);治疗后对照组BAEP明显改善(P<0.05),SEP改善更为显著(P<0.01),GCS评分明显升高(P<0.05),HBO组BAEP、SEP改善均有统计学意义(P<0.01),GCS评分提高有统计学意义(P<0.01);治疗后HBO组BAEP、SEP异常率与对照组比较差异有统计学意义(P<0.01),GCS评分与对照组比较差异有统计学意义(P<0.05);伤后6个月GOS评分显示HBO组预后良好患者较对照组明显增多(P<0.01),死亡率则明显降低(P<0.05).结论 HBO可明显改善中重型颅脑损伤患者BAEP及SEP的异常情况,提高临床疗效.