共查询到17条相似文献,搜索用时 375 毫秒
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采用专用的白细胞、红细胞和血小板3类生物粒子合成模拟人的血液,按照国家一级标准物质研制规范制备血细胞计数标准物质,采用显微图像分析法为血细胞计数标准物质定值,对该血细胞计数标准物质的定值结果及不确定度评定、均匀性检验、稳定性检验过程进行分析,将该血细胞标准物质定值结果与国际参考方法的测定结果进行比对。结果证明:本血细胞计数标准物质适于血细胞分析仪的校准与计量检定。 相似文献
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选择商品化的13X分子筛颗粒作为微孔孔容和孔径标准物质候选材料,利用交叉缩分方法对标准物质样品进行分装;从分装后的标准物质样品中随机抽取样品来检验其均匀性、稳定性;采用国际公认的氩气物理吸附方法,通过与欧洲经济共同体IRMM标准物质BCR-704比较测量的方式对标准物质样品进行定值。结果表明,经均匀性、稳定性检验,所研制的微孔孔容和孔径标准物质GBW(E)130366具有良好的均匀性和稳定性(至少12个月);微孔孔容和孔径分别为0.242 cm3/g和0.668 nm;与国内外同类标准物质相比,GBW(E)130366填补了国内空白,其相对不确定度(3.3%和2.8%)达到国际同类标准物质的先进水平。 相似文献
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《计量技术》2021,(6)
本课题研制了乙腈中展青霉素的溶液标准物质1种,并已成功申报为国家二级标准物质(GBW(E)100674)。该溶液标准物质以展青霉素纯度国家二级标准物质(GBW(E)100673)为原料,采用重量容量法配制。依据JJF1343-2012《标准物质定值的通用原则及统计学原理》的要求,本研究采用液相色谱法对乙腈中展青霉素溶液标准物质进行均匀性、短期稳定性和长期稳定性的评价。定值不确定度包含原料纯度、溶液配制、均匀性、短期稳定性和长期稳定性五个方面引入的不确定度。最终,该溶液标准物质GBW(E)100674的定值结果为100μg/m L,不确定度为2%。本研究研制展青霉素溶液标准物质的量值具有溯源性和准确性,可以支持国家食品安全检测的需要。 相似文献
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《计量技术》2021,(7)
研制了液相色谱-质谱联用仪(LC-MS)校准用甲醇水中咖啡因溶液标准物质并进行不确定度评定。以咖啡因纯品、色谱级甲醇和实验室一级用水为原材料,利用质量平衡法对咖啡因纯品进行纯度核验,利用基准方法重量—容量法配制浓度9.94 mg/L甲醇水中咖啡因溶液标准物质。采用液相色谱法对9.94 mg/L甲醇水中咖啡因标准溶液和国家二级标准物质GBW(E)130453进行量值比对,并对溶液标准物质的均匀性、短期稳定性和长期稳定性进行考察。结果表明研制的9.94 mg/L的甲醇水中咖啡因溶液标准物质的均匀性和稳定性良好,相对扩展不确定度为2%(k=2),有效期为12个月。 相似文献
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根据斑点酶联免疫分析仪的技术参数,结合酶联斑点的培养生长特性,采用AutoCAD设计模拟斑点图形,研制了模拟斑点标准物质,经过均匀性和稳定性检验,由八家实验室采用人工识别计数的方法进行协同定值,并进行不确定度评估。结果表明,该标准物质均匀性良好,在实验室室温避光条件下保存,稳定性在1 a以内,并成功应用到斑点酶联免疫分析仪的计量校准工作中,对仪器示值误差和重复性的计量特性进行实验研究,为仪器日常的校准工作以及国家计量校准规范的制定提供了实验基础。 相似文献
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为了保证小鼠生物法、荧光衍生法、质谱法等对腹泻性贝类毒素检测结果的准确、可靠和可比,以紫贻贝为基体,采用添加法研制了一种含腹泻性贝类毒素软海绵酸(OA)的冻干粉形式的贝类毒素基体标准物质.采用LC-MS/MS法,以多家定值的方式对标准物质中的OA进行定值.均匀性检验结果表明该样品均匀,短期稳定性和6个月的稳定性考察表明样品稳定性良好.经过对影响定值结果的称样量、定容、校准物、校准曲线等因素的考察,进行不确定度评定,标准物质中OA的含量及不确定度为2.96土0.50μgOA/g(k=2).该标准物质可以用于腹泻性贝类毒素检测过程的方法验证与质量控制等. 相似文献
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The flash point is an important indicator for the flammability of the liquid materials and also in the development of safe practices for handling and storage of these materials. The production of certified reference materials is essential to guarantee the performance of the flash point measurement apparatus so that it can be trusted and acceptable for its intended use. In this work lubricant oils of high molecular weight hydrocarbons (HM1, and HM2) were tested as certified reference materials in accordance with ISO guide 34 and 35 by using the high flash point temperature detector Cleveland-open cup as per ASTM D-92. The selected oils were tested for uncertified properties like pour point, viscosity, cloud point, density, and total acid number. The thermal analysis techniques DSC, and TGA were used to ensure the thermal stability of the lubricant oils and its ability to be used as high temperature flash point reference material. The certified value of the flash point temperature was assigned upon evaluation of the data acquired in an inter-laboratory comparison involving expert laboratories using the same measurement method. The certified values of the candidate reference materials with expanded uncertainty (coverage factor K = 2, approximate 95% confidence level) calculated using the results of the characterization, calibration (organizer lab), homogeneity, and stability assessment were 232 ± 9 °C for HM1, and 242 ± 10 °C for HM2. 相似文献
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Certified reference materials are essential tools for calibration of measuring instruments, validation of analytical methods and assuring quality of measurement results. However, in the case of water content in honey, which is used to determine the quality and the marketability of honey, there is a lack of matrix reference materials. Certified reference material for water content in honey has been developed by the National Institute of Standards, Egypt. This article describes production of the material from processing to value assignment. Characterization of the material was carried out by refractometric and Karl Fisher titration procedures, where homogeneity and stability studies were carried out by Karl Fisher titration method. The measurement results were statistically analysed and weighted mean was calculated as assigned value. The certified value and expanded uncertainty were found 16.24 ± 0.33 g/100 g, respectively. 相似文献
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将筛选后的转基因水稻TT51-1和非转基因水稻明恢63种子分别冷冻研磨成粉末,采用重量法配置了5个不同水平的标准物质。经检验该标准物质的均匀性良好,可在4℃保存条件下存储1年。标准物质采用重量法的质量分数作为标准值,数字PCR测定拷贝数分数作为参考值,通过转基因水稻与非转基因水稻种子粉末提取效率比值校准的数字PCR定值结果与重量法质量分数定值结果之间具有等效一致性,该标准物质可用于转基因水稻TT51-1的定量PCR检测及其特异性检测方法的评价。 相似文献
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报导了脱脂奶粉成分分析标准物质的制备,即按要求生产的脱脂奶粉经低温真空干燥、过筛控制粒度、V型混匀器混匀、N_2气氛下分装和低温干燥保存等步骤。所制备的样品按国家一级标准物质研制的规范程序进行均匀性和稳定性检验。并使用13种分析技术和20余种分析方法对18种成分元素进行定值。测定结果表明:样品均匀性良好,稳定性跟踪已大于一年,量值准确。 相似文献