SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses

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Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer

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Canonical BAF complex activity shapes the enhancer landscape that licenses CD8+ T cell effector and memory fates

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The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination

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Single-cell protein expression profiling resolves circulating and resident memory T cell diversity across tissues and infection contexts

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Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes

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BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

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Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection

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COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses

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CD8+ T cells promote HIV latency by remodeling CD4+ T cell metabolism to enhance their survival,quiescence, and stemness

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Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

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CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor

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Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection

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Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation

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Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup

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Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells

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Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection

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CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection

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A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult

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Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy

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