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1.
Michael T.M. Wang Kalaivarny Ganesalingam Chee Seang Loh Trisha Alberquerque Suhaila Al-Kanani Stuti L. Misra Jennifer P. Craig 《Contact lens & anterior eye》2017,40(1):53-58
Purpose
To assess the effects of two weeks of regular phospholipid liposomal spray application on lipid layer grade, tear film stability, subjective comfort, visual acuity, and lipid deposition in silicone hydrogel contact lens wearers.Methods
Thirty-one existing contact lens wearers were enrolled and fitted with two week planned replacement silicone hydrogel contact lenses (Acuvue® Oasys®) in a prospective, randomized, paired-eye, investigator-masked trial. A phospholipid liposomal spray (Tears Again®) was applied to one eye (randomized) four times daily for two weeks. LogMAR high contrast visual acuity (VA), low contrast glare acuity (LCGA), non-invasive tear film break-up time (NIBUT), and lipid layer grade (LLG) were measured at baseline and day 14, in both treated and control eyes. Subjective comfort relative to baseline, and spectrofluorophotometric assessment of contact lens surface lipid deposition were also assessed on day 14.Results
All measurements did not differ at baseline between treated and control eyes. Lipid layer thickness and tear film stability were increased on day 14 in treated eyes (all p < 0.05), but not in control eyes (all p > 0.05). A greater proportion of participants reported improved comfort in the treated eye relative to the control eye (p = 0.002). There were no significant differences in visual acuity or in contact lens surface lipid deposition, between treated and control eyes, on day 14 (all p > 0.05).Conclusion
The phospholipid liposomal spray increased tear film stability, lipid layer thickness and subjective comfort in silicone hydrogel contact lens wearers, without adversely affecting visual acuity or contact lens surface lipid deposition. 相似文献2.
Purpose
To compare vision correction preferences, refractive error, and gender of non-presbyopes and presbyopes.Methods
Adults who wear spectacles or contact lenses completed a survey about refractive correction opinions and refractive error was measured.Results
Of the 304 subjects, 38.2% were presbyopic (≥40 years) and 59.2% were female. Spectacles were the primary vision correction for 78.0% of subjects. Compared to contact lens wearers, the proportion of presbyopes was higher (p = 0.006) in spectacle wearers. There was no difference in the proportion of presbyopes and non-presbyopes who have tried contact lenses (p = 0.2) or who would prefer to wear contact lenses (p = 0.2). In contact lens wearers, there was no difference in the proportion of presbyopes and non-presbyopes with a history of temporary discontinuation (p = 0.9). Within the contact lens wearing group, there was no refractive error difference between presbyopes and non-presbyopes (spherical equivalent p = 0.6; power vector J0 p = 0.5; power vector J45 p = 0.4; anisometropia p = 0.2). Overall, contact lens wearers were more likely to be female (p = 0.004). There was no difference in gender in presbyopic and non-presbyopic contact lens wearers (p = 0.5).Conclusions
Presbyopes and non-presbyopes have similar opinions about spectacles and contact lenses. Presbyopes of all refractive errors prefer contact lens correction when good vision and comfort can be achieved. Eye care providers should not assume that presbyopia, refractive error, or gender are factors that preclude a patient from being interested in contact lens wear. 相似文献3.
Michael T.M. Wang Irene Cho Soo Hee Jung Jennifer P. Craig 《Contact lens & anterior eye》2017,40(4):236-241
Purpose
To compare the effects on tear film parameters and contamination in cosmetic eyeliner wearers, after single application of two lipid-based dry eye treatments: a lipid-containing lubricant eye drop and a phospholipid liposomal spray.Methods
Fifty participants were enrolled in a prospective, randomised, paired-eye, investigator-masked trial. Pencil eyeliner (Body Shop® Crayon Eye Definer) was applied to the upper eyelid periocular skin of both eyes, anterior to the lash line. Baseline tear film quality was assessed fifteen minutes after eyeliner application. A lubricant drop (Systane® Balance) was then applied to one eye (randomised), and liposomal spray (Tears Again®) to the contralateral eye. Tear film contamination, lipid layer grade, non-invasive tear film break-up time and tear evaporation rate were evaluated fifteen minutes post-treatment and compared to pre-treatment values.Results
Pre-treatment measurements did not differ between eyes assigned to lubricant drop and liposomal spray. Tear film contamination was observed in a greater proportion of eyes following both treatments (both p < 0.05), with no significant difference between treatments (p = 0.41). Both treatments improved lipid layer thickness (both p ≤ 0.01), but effected no significant change in non-invasive tear film break-up time or tear evaporation rate (all p > 0.05). Changes in tear film parameters did not differ between treatments (all p > 0.05).Conclusions
Both the lipid-containing lubricant eye drop and phospholipid liposomal spray result in clinically apparent tear film contamination in eyeliner cosmetic wearers. Although both treatments effected an increase in lipid layer thickness, neither displayed clinical efficacy in improving tear film stability. 相似文献4.
Aim
To analyze the demographics, risk factors, clinical and microbiological characteristics of cases of bilateral simultaneous infective keratitis.Methods
In this retrospective case series, patients with clinical evidence of bilateral simultaneous infective keratitis were identified from January 1, 2011 to August 31, 2016. Demographics, risk factors, clinical and microbiological characteristics, and treatment outcomes were analyzed.Results
Five patients (ten eyes) with bilateral simultaneous infective keratitis were identified. The mean age was 32.8 years (SD, ± 8.8; range, 24–44). All the patients were disposable soft contact lens wearers before presentation. The average size of the infiltrate was 4.76 mm2 (SD ± 9.0; range, 0.2–31.34). A total of 4 types of bacteria were isolated, with Pseudomonas aeruginosa being the most frequently isolated bacteria involving 5 eyes of four patients. Infection resolved with medical treatment in 9 eyes, 1 patient required therapeutic corneal transplantation for impending corneal perforation. The average time taken for infection to resolve was 6.7 days (SD ± 4.5; range, 2–16).Conclusions
In this case series, the most common risk factor of bilateral simultaneous microbial keratitis was use of soft disposable contact lens and the most commonly isolated bacteria was Pseudomonas aeruginosa. Bilateral simultaneous infective keratitis is uncommon and is a serious complication of contact lens use in immunocompetent adult patients. 相似文献5.
Kate Gifford Paul Gifford Peter L. Hendicott Katrina L. Schmid 《Contact lens & anterior eye》2017,40(3):184-189
Purpose
To compare near point binocular vision function of young adult myopes wearing orthokeratology (OK) lenses to matched single vision soft disposable contact lens (SCL) wearers.Methods
A retrospective clinical record analysis of all OK wearers (18–30 years) presenting over an 18 month period was undertaken. Data was extracted for 17 OK wearers, with 17 SCL wearers matched for age, refractive error and duration of contact lens wear. Binocular vision data included horizontal phoria (phoria), horizontal base-in (BIFR) and base-out fusional reserves (BOFR) and accommodation accuracy (AA).Results
The OK group was 25.8 ± 3.2 years, with a duration of wear of 45.7 ± 25 months and refractive error of R ?2.09 ± 1.23D, L ?2.00 ± 1.35D. Compared to matched SCL wearers the OK group were significantly more exophoric (OK ?2.05 ± 2.38Δ; SCL 0.00 ± 1.46Δ, p = 0.005) and had better accommodation accuracy (OK 0.97 ± 0.33D; SCL 1.28 ± 0.32D, p = 0.009). BIFR and BOFR were not different in the two groups. Frequency histograms showed that more SCL wearers had high lags of accommodation (AA ≥ 1.50D: 8 SCL,2 OK) and esophoria (≥1Δ: 5 SCL,1 OK) than OK wearers. A positive correlation was found between refraction and phoria in the SCL group (r = 0.521, p = 0.032).Conclusion
Young adult myopes wearing OK lenses display more exophoria and lower accommodative lags at near compared to matched single vision SCL wearers. Young adult myopes with specific binocular vision disorders may benefit from OK wear in comparison to single vision SCL wear. This has relevance to both the visual acceptance of OK lenses and in managing risk factors for myopia progression. 相似文献6.
Purpose
To report a case of lens discontinuation in a long term orthokeratology (OK) lens wearer and describe regression in refraction, corneal topography, and corneal thickness over 408 days after lens discontinuation. Furthermore, the outcome of subsequent LASIK treatment is also reported.Case report
A 41 year old Caucasian female who had been previously wearing OK lenses for 13 years discontinued lens wear in the left eye to consider refractive surgery in that eye. The greatest changes in subjective and objective refractions, corneal topography and thickness occurred during the first 28 days after lens discontinuation. Subjective refraction did not reach baseline values, but corneal topography parameters returned to pre-OK values after 408 days of no lens wear. The patient then received successful refractive surgery treatment in that eye, achieving uncorrected visual acuity of 0.00 LogMAR units, and residual refractive error within ±0.50 D of emmetropia.Conclusion
The period of lens discontinuation required for long term OK lens wearers before refractive surgery is likely to vary between individuals and the patient described in this case report required a significant period of lens discontinuation of at least one year before being considered suitable for refractive surgery. 相似文献7.
Purpose
The aim of this work was to investigate the locus and extent of vitronectin (Vn) deposition on ex vivo contact lenses and to determine the influence of wear modality together with surface and bulk characteristics of the lens material.Methods
The quantity and location of Vn deposition on the surfaces of contact lens materials was investigated using a novel on-lens cell attachment assay technique.Results
Vn mapping showed that deposition resulted from lens-corneal interaction rather than solely from the tear film. Higher cell counts on the posterior surface of the lenses were determined in comparison to the anterior surface. Overall gross Vn deposition was greater for high water content-low modulus materials (117 ± 4 average cell count per field) than low water content-high modulus materials (88 ± 6 average cell count per field).Conclusions
The role of Vn in plasmin regulation and upregulation is widely recognised. The findings in this paper suggest that the locus of Vn on the contact lens surface, which is affected by material properties such as modulus, is potentially an important factor in the generation of plasmin in the posterior tear film. Consequently, the potential for materials to affect Vn deposition will influence lens-induced inflammatory processes. 相似文献8.
Purpose
To investigate effect of topical anaesthetic (TA) during gas permeable (GP) contact lens (CL) fitting on subjective and objective measures of patient anxiety.Methods
47 subjects (mean ± sd age = 26.9 ± 4.9 years; soft CL wearers, 18, neophytes, 29). Each subject randomly assigned to Group A or B, and attended on two occasions, one week apart. First visit: subject received bilaterally either a single drop of TA (0.5% proxymetacaine) (Group A) or placebo (0.9% saline) (Group B) prior to GP CL application. No drops were instilled at second visit. Each visit mimicked a GP CL fitting. At each visit, patient anxiety was assessed either subjectively (visual analogue scale (VAS)) or objectively (skin conductance (SC)), as well as anterior ocular health.Results
Visit 1: GP CL trial produced small increases in hyperaemia and corneal staining, but no difference associated with TA use. Visit 2: increases in staining and hyperaemia were observed, but hyperaemic responses significantly less than at Visit 1, for both groups. Corneal staining also less, but not statistically significant. VAS scores indicated subjects who received TA during Visit 1 were significantly less anxious at Visit 2. Visit 2: comfort slightly reduced for subjects who received TA at Visit 1, and significantly increased for subjects who received placebo. Use of TA reduced anxiety during lens adaptation period compared with subjects receiving placebo.Conclusions
TA use during GP CL fitting has potential patient benefits: improved first-time GP CL wear comfort, reduced anxiety during adaptation, reduced anxiety prior to subsequent GP CL wear. 相似文献9.
Jennie Diec Thomas Naduvilath Daniel Tilia Eric B. Papas Percy Lazon de la Jara 《Contact lens & anterior eye》2017,40(6):367-381
Purpose
To describe a ranked symptoms scale (RSS) discriminating subjective responses in contact lens (CL) wear in various situations.Method
Forty experienced clinical trial participants were interviewed for their perceptions of ocular comfort scales, resulting in a numerical RSS. For further evaluation, 20 CL wearers enrolled into a prospective, randomised, crossover trial. Two silicone-hydrogel CLs and a lens care solution (LCS) [Combinations A & B] were selected based on prior performance identifying best/worst combinations for end-of-day comfort. The RSS and a numerical rating scale (NRS) were administered at two time-points (insertion/removal) on alternating days for 6 days.Results
Both NRS and RSS showed acceptable internal consistency for comfort, vision and handling (Cronbach alpha = 0.71 for both scales) and similar repeatability for comfort and handling (coefficients-of-repeatability within 0.1 and 0.2 units, respectively, for each scale). The NRS and RSS discriminated differences between combinations for comfort (p ≤ 0.031) and vision (p ≤ 0.026) at both time-points. Additionally, the RSS showed lens/edge awareness influenced discomfort the most, ranking higher at insertion (p = 0.038) and higher for Combination-B at both time-points (p ≤ 0.002). Symptoms of dryness and tired eyes increased for both combinations at removal (p < 0.02). The RSS also showed haziness and blurred distance vision influenced vision dissatisfaction with Combination-B at lens removal (p ≤ 0.038) while eye strain/headache increased for both combinations by time of removal (p ≤ 0.013).Conclusions
The RSS is able to discriminate subjective responses between combinations and time-of-day. The RSS’s ability to rank symptoms may be a useful tool in understanding perceptions of discomfort or dissatisfaction with CL wear. 相似文献10.
Purpose
This study aims to evaluate the settling of a scleral lens and if this process is influenced by the nature of the fluid layer.Methods
A prospective, non-randomized control study was performed using an 18 mm scleral lens. They were fitted with a central clearance of 400 um at insertion. One eye was randomly assigned to be fitted with a non-preserved gel solution of carboxymethylcellulose, while the other was inserted with non-preserved saline. Measurements of clearance in 3 locations were taken (OCT) at baseline, every 30 min up to 1h30 post insertion and every 2 h thereafter up to 6h00 of wear. A two-way repeated measure analysis of variance (liquids × times) was used to test central, nasal and temporal fluid thickness.Results
Following 6 h of wear, the 18 mm lens had a mean central settling of 70.0 ± 9.8 μm, 36.7 ± 9.8 μm of which occurred within the first 30 min of wear. There was no significant difference between lenses filled with non-preserved saline to those with non-preserved gel. However, a paired comparison concluded to a significant difference between mean nasal settling (41.4 μm) and temporal settling (20.4 μm).Conclusion
With respect to the lens studied, current results suggest that practitioners can evaluate the lens 30 min post insertion and can estimate the amount of fluid that will remain after lens stabilization by doubling the value obtained initially. The use of non-preserved saline or non-preserved more viscous solution to fill the lens does not influence its settling. 相似文献11.
Sarah La Porta Weber Rossen Mihaylov Hazarbassanov Alex Nasaré José Álvaro Pereira Gomes Ana Luisa Hofling-Lima 《Contact lens & anterior eye》2017,40(3):151-156
Purpose
To evaluate conjunctival impression cytology and HLADR expression changes after wearing scleral contact lenses (ScCLs) for moderate to severe dry eye disease (DED).Design
Prospective interventional case series.Methods
Forty-one eyes from 25 patients with moderate to severe DED were evaluated for Esclera ScCL treatment. Best-corrected visual acuity (BCVA) and slit-lamp findings were assessed. Impression cytology specimens were obtained from DED patients at the baseline and after wearing ScCLs for 12 months. The impression cytology specimens were analyzed using morphological results score, and HLA-DR positive cells were detected and quantified. The values were compared to assess the IC changes after wearing ScCLs.Results
Forty-one eyes from 25 patients were fitted with ScCLs to manage DED. The underlying diseases were Stevens-Johnson syndrome (22 eyes), Sjogren’s syndrome (11 eyes), graft-versus-host disease (2 eyes), dry eye after keratomileusis (2 eyes) and undifferentiated ocular surface disease (4 eyes). The HE-PAS impression cytology score did not differ significantly before and after wearing ScCLs for 12 months in DED patients (p > 0.05). The percentage of eyes expressing the HLA-DR antigen in the temporal conjunctiva after wearing ScCL for 12 months significantly increased in patients with Sjogren’s syndrome (11.11% to 66.66%; p = 0.0498). In groups with Stevens Johnson syndrome and other ocular surface disorders, we did not observe statistically significant differences (p > 0.05).Conclusions
The ScCLs did not change the parameters used to evaluate inflammatory processes, which were measured using conjunctival impression cytology and HLA-DR expression, except in Sjogren syndrome, in which there was an unexpected increase in HLA expression. 相似文献12.
Michael J. Doughty 《Contact lens & anterior eye》2017,40(2):109-115
Purpose
To assess if polymegethism and pleomorphism were evident in corneal endothelium after medium-term rigid gas permeable (RGP) contact lens wear.Methods
In a cross-sectional observational study over 12 years, single images of the central region of the corneal endothelium of one eye of 46 subjects were taken with a non-contact specular microscope, along with a measure of central corneal thickness (CCT). The images were printed onto A3-sized paper and 100 cells/image measured by planimetry.Results
Subjects aged between 20 and 32 years, with an average cumulative RGP wear of 6.0 +/? 1.6 years (range 3–9 years) were assessed; 26 of the subjects were Caucasian and 20 were Asian. The mean CCT was 0.515 +/? 0.027 mm. The group cell area value was 401 +/? 42 sq micron to give an estimated endothelial cell density (ECD) of 2520 +/? 273 cells/sq mm. As compared to a historical database, most endothelia (37/46) showed some changes with the mean coefficient of variation on cell area (COV) being 36.7 +/? 8.0% and the percentage of 6-sided (HEX) being 51.8 +/? 8.8%. There were modest correlations between years of RGP wear and both COV (p = 0.009, r spearman = 0.424) and HEX (p = 0.025, r spearman = ?0.291), but not for ECD or CCT.Conclusions
Corneal endothelial polymegethism appears to be a commonplace consequence of RGP lens wear with the magnitude of the change being related to the cumulative duration of the lens wear. 相似文献13.
Purpose
To evaluate early visual rehabilitation, post-operative pain, epithelial healing and haze after transepithelial photorefractive keratectomy (TransPRK) using the SmartPulseTechnology (SPT) of Schwind Amaris (Schwind eye-tech-solutions GmbH, Kleinostheim, Germany).Methods
This was a retrospective comparative evaluation of a cohort of myopic patients undergoing TransPRK with SPT (group 1), with one matched control group that underwent conventional TransPRK (group 2). All cases had a 6-month post-operative follow-up including visual acuity and slit-lamp examination. Subjective evaluation of pain was recorded post-operatively.Results
49 eyes of 25 patients in group 1 and 40 eyes of 20 patients in group 2 were enrolled. The patients’ visual rehabilitation was significantly faster in group 1, one day and one week post-operatively (P < 0.05). From one month onward there was no significant difference between the groups. The epithelial defect size was significantly smaller on post-operative days 1 and 2 for group 1 (P < 0.05 in both cases). The pain score was also significantly less in group 1 (P < 0.05). The haze level had no significant difference between the groups at any post-operative point (P > 0.05).Discussion
TransPRK using SPT provides promising results in the early post-operative period. Visual rehabilitation, re-epithelialization and pain were faster in the early post-operative period in group 1 in comparison with group 2. Haze formation was not significantly different between the two groups; however, it was consistently less in group 1. 相似文献14.
Aoife Lloyd-McKernan Luisa Simo Mannion Veronica O’Dwyer 《Contact lens & anterior eye》2017,40(5):301-310
Purpose
To examine the influence of previous soft contact lens (SCL) wear on corneal refractive surgery (CRS) outcomes when SCL wear is ceased for two weeks versus twenty-four hours, and also when compared to no wear, prior to CRS.Methods
A retrospective examination of CRS patient records was carried out for two groups of patients- who ceased SCL wear for two weeks (n = 45) and for twenty-four hours (n = 49) prior to CRS and compared to a non-contact lens (NCL) control group (n = 45 and n = 49, respectively). CRS outcomes (efficacy, predictability, visual acuity and refractive error) were compared pre-operatively and one and six months post-operatively.Results
One month post-operative results found unaided distance visual acuity (UDVA) was significantly better for LASEK/PRK patients who had ceased SCL wear for two weeks prior to CRS (?0.05 ± 0.09), compared with the NCL group (0.02 ± 0.09; p = 0.04). Furthermore, six month post-operative results found UDVA was significantly better for both LASIK and LASEK/PRK patients who had ceased SCL wear for two weeks prior to CRS, and for LASEK/PRK patients who had ceased SCL wear for twenty-four hours prior to CRS compared with the NCL group.Conclusions
Given the current setup and methods followed, it was concluded that previous SCL wear had no negative impact on visual outcomes following CRS compared with a NCL control group, regardless of previous SCL cessation time prior to CRS. 相似文献15.
Jennifer K. Mooi Michael T.M. Wang Joevy Lim Andreas Müller Jennifer P. Craig 《Contact lens & anterior eye》2017,40(3):170-174
Purpose
To compare clinical tear film break-up time measurements obtained non-invasively, with those measured following minimal and conventional volumes of fluorescein instillation.Methods
Forty-one subjects (20 male, 21 female, mean ± SD age 34 ± 11 years), with or without dry eye, participated in a prospective cross-over study. Tear film break-up time was measured by the Tearscope Plus? with fine grid insert. Measurements were made in triplicate, with no fluorescein instillation (NIBUT), then following application of a minimal volume of 1 μl fluorescein from the Dry Eye Test? (mTBUT), and finally with 15–30 μl of fluid instilled via a conventional fluorescein strip (TBUT). A fifteen-minute interval between each set of measurements minimised the risk of residual contamination effects.Results
All three techniques displayed statistically significant pairwise correlation (all p < 0.001). TBUT values were significantly shorter than both NIBUT (geometric mean 8.6 s versus 10.9s, p = 0.03) and mTBUT (geometric mean 8.6 s versus 10.6s, p = 0.03), and demonstrated narrower spread (both p < 0.05). No significant differences were detected between NIBUT and mTBUT (all p > 0.05).Conclusions
Tear film break-up time values measured with conventional fluorescein instillation were shortened, while minimal fluorescein instillation and non-invasive methods produced comparable readings. This suggests that minimising instilled volumes can reduce the impact of fluorescein on clinical measurements of tear film stability. 相似文献16.
Hassan Hashemi Asghar Beiranvand Abbasali Yekta Amir Asharlous Mehdi Khabazkhoob 《Contact lens & anterior eye》2017,40(2):104-108
Purpose
To examine the diagnostic validity of different corneal biomechanical parameters for the detection of early keratoconusMethods
Sixty-one eyes with a diagnosis of early keratoconus and 61 topographically normal eyes were enrolled in the study. All participants underwent testing with the Ocular Response Analyzer (ORA), and 40 indices from each cornea were included in the analysis.Results
The mean (standard deviation: SD) of keratometry and central corneal thickness in keratoconic corneas was 46.9 (2.5) diopter (D) and 473 (31) μm, respectively. Of the 40 evaluated indices, 32 showed a significant difference between the two groups using t-test (p < 0.05). According to the results of logistic regression, the indices of height from the lowest to the highest point in peak 2 (H21) and corneal resistance factor (CRF) with R2 = 0.79 were the best predictors of early keratoconus (p < 0.001). H21 ≤190 with a sensitivity and specificity of 87% and 91.8%, respectively, and CRF ≤ 8.6 with sensitivity and specificity of 87% and 85.3%, respectively, yielded an overall diagnostic accuracy of 97.3%.Conclusion
This study results point to the important role of novel waveform-derived indices measured by ORA, along with conventional biomechanical indices, for the early diagnosis of keratoconus. The best predictors of keratoconus in its early stages are H21 and CRF which showed very high sensitivity and specificity for the detection of early keratoconus. 相似文献17.
Alejandra Consejo Maciej M. Bartuzel D. Robert Iskander 《Contact lens & anterior eye》2017,40(5):293-300
Purpose
To assess whether short-term soft contact lens wear alters the anterior eye surface.Methods
Twenty-two neophyte subjects wore soft contact lenses for a period of five hours. Topography based corneo-scleral limbal radius estimates were derived from height measurements acquired with a corneo-scleral profilometer. Additionally, central corneal thickness (CCT), anterior chamber depth (ACD), corneal curvature radius (R) and white-to-white (WTW) diameter were acquired with an OCT-assisted biometer. Measurements were obtained without lens wear (baseline), immediately after lens removal following five hours of wear and three hours after lens removal.Results
Short-term soft contact lens wear significantly modifies corneo-scleral limbal radius (mean ± SD: 130 ± 74 μm, p << 0.001) and the changes are repeatable. In contrast, the WTW diameter and R were not modified. ACD and CCT were significantly affected but no significant correlations were found between the increment of the limbal radius and the decrease in ACD and CCT. Limbal radius increment was reversed three hours after lens removal for 68% of the subjects but the time course of this reversal was not uniform.Conclusions
It is possible to accurately quantify limbal radius changes as a consequence of soft contact lens wear. The increment in the limbal diameter could reach over 0.5 mm but that alteration does not correspond to changes in WTW diameter and it was not observable to the examiner using a slit lamp. Assessing topographical limbus after contact lens wear could be a tool to optimize the selection of the contact lens, from the perspective of anterior eye surface changes. 相似文献18.
Corneo-scleral contact lenses in an uncommon case of keratoconus with high hyperopia and astigmatism
Esteban Porcar Juan Carlos Montalt Enrique España-Gregori Cristina Peris-Martínez 《Contact lens & anterior eye》2017,40(5):351-356
Purpose
To analyse the visual quality achieved by fitting corneo-scleral contact lenses (CScL) in an uncommon case of bilateral keratoconus, high hyperopia and astigmatism.Methods
A 45-year-old man presented for eye examination due to the unsatisfactory quality of his vision wearing soft toric contact lenses. He presented high hyperopia and astigmatism with bilateral keratoconus. He was fitted with CScL to correct his irregular astigmatism and ocular aberrations. A diagnostic trial set was used in the fitting process and he was assessed according to standardised fitting methodology. Visual acuity, corneal topography, biometry and ocular aberrations were evaluated. The follow-up period was 1 year.Results
The best spectacle-corrected visual acuity was 20/32 with +8.00/?4.50 × 30° for the right eye (RE) and 20/25 with +7.75/?2.25 × 120° for the left eye (LE). After CScL fitting, visual acuity was improved to 20/20 and 20/16 for the RE and LE, respectively. The patient wore these contact lenses an average of 13 h a day. The total high order aberrations decreased by approximately 79% in the RE (2.37–0.50 μm) and 47% in the LE (1.04–0.55 μm) after CScL fitting. Visual quality and wearing time were maintained after 1 year wearing CScL. In addition, no adverse ocular effects were found during this period.Conclusion
The present case report describes how the patient had CScL fitted successfully for management of keratoconus with high hyperopia and astigmatism. They provided optimal visual quality, along with prolonged use times and no adverse effects to the cornea. 相似文献19.
Hassan Hashemi Hadith Rastad Mohammad Hassan Emamian Akbar Fotouhi 《Contact lens & anterior eye》2017,40(4):213-216
Purpose
To estimate the prevalence of Meibomian gland dysfunction (MGD) and determine the associated factors in the general population in Iran.Methods
This cross-sectional study is based on the data from the second phase of the Shahroud Eye Cohort Study conducted in 2014. Of the 4737 participants of the second phase, data was available for 4700 people; their mean age was 55.9 ± 6.2 years and 2768 (58.9%) were women. Diagnosis of MGD was made based on the classification of the International Workshop on MGD as judged by the examining ophthalmologist. The prevalence of MGD was summarized as percentage and 95% confidence intervals (CI), and related factors were studied through simple and multiple logistic regressions.Results
The diagnosis of MGD in at least one eye was recorded for 1235 (26.3%) participants; the prevalence of unilateral and bilateral MGD was 26.3% (95% CI: 24.5-28.1) and 26.1% (95% CI: 24.3–27.9), respectively. In the multiple logistic regression analyses, MGD significantly correlated with pinguecula [odds ratio (OR) = 1.3, 95% CI: 1.12–1.50], hypertension (OR = 1.34, 95% CI: 1.11–1.61), high-density lipoprotein (HDL) level (OR = 0.0992, 95% CI: 0.986–0.999), diabetes mellitus (OR = 0.83, 95% CI: 0.71–0.97), and years of education (OR = 0.98, 95% CI: 0.96–0.99).Conclusions
MGD prevalence in this study was lower than the rates reported in other studies on Asian populations. Besides HDL level, MGD is associated with another ocular surface disorder, namely pinguecula, as well as certain systemic diseases such as hypertension and diabetes mellitus. These associations should be taken into consideration when diagnosing MGD. 相似文献20.