嗓音训练应用于声带息肉术后的效果评价

目的 探讨嗓音训练应用于声带息肉术后的疗效。 方法 选取92例接受声带息肉切除术患者作为研究对象,所有患者随机分为实验组(n=46)与对照组(n=46)两组。两组患者均行喉显微声带息肉切除术,对照组术后给予金嗓散结丸口服治疗4周,实验组在对照组基础上术后1周起联合嗓音训练治疗3周,术后4周两组同时结束治疗。比较两组患者治疗前后嗓音障碍指数(VHI)评分及嗓音声学参数值。 结果 脱落病例6例,86例完成研究。治疗前实验组与对照组VHI评分及嗓音声学参数值差异无统计学意义(P>0.05);治疗后两组VHI评分及嗓音声学参数值较治疗前均改善(P<0.001);治疗后实验组较对照组VHI评分及嗓音声学参数值显著改善。 结论 嗓音训练可促进声带术后功能恢复,提高嗓音质量,疗效显著。     

咽喉反流与发声障碍的相关性研究

目的:探讨咽喉反流的嗓音学特征及其对患者生活质量的影响,分析主客观评估方法的相关性。方法:对196例可疑有咽喉反流的患者行一般情况调查、电子鼻咽喉镜检查、反流症状指数量表(RSI)和反流检查计分量表(RFS)评估,将其中RSI评分>13分、RFS评分>7分定为阳性。将2个量表评分均为阳性的100例患者作为研究对象,进一步进行嗓音障碍指数量表(VHI)评估、嗓音声学分析及电声门图检查,并与健康对照组比较。结果:男女基频均比健康对照组降低,基频微扰、振幅微扰及标准化噪声能量增高,接触率降低,最大发声时间缩短,与健康对照组比较,差异均有统计学意义(均P<0.01)。VHI量表评估生理P评分最高,其次为功能F评分,情感E评分最低。咽喉反流患者的RSI与VHI有一定相关性(P<0.05),而RFS与RSI、VHI无明显相关性(P>0.05)。咽喉反流患者的嗓音障碍指数评估示生理、功能和情感之间明显相关。结论:嗓音声学分析及电声门图检测从客观上提示咽喉反流相关的嗓音障碍疾病严重影响了喉的发声功能,使基频下降、声带振动不稳定、声门闭合不良及声门接触时间缩短。主客观评估方法的相关性结果提示具有明显咽喉反流症状的患者并不一定具有明显的咽喉反流体征。     

嗓音训练治疗声带小结的疗效观察

目的探讨嗓音训练对声带小结患者发声障碍的治疗效果。方法对21例声带小结患者进行嗓音训练,包括嗓音教育和发声训练,根据"呼吸-发声-共鸣"平衡原理,采用喉部按摩、无声练习及发大开口咽音的训练方法,每周训练一次,每次1~2小时,共5次。训练前后对患者进行嗓音障碍指数量表(VHI)评估、GRBAS评估、动态喉镜检查、空气动力学检测、计算机嗓音声学分析,比较治疗前后评估结果。结果 21例患者治疗后VHI评分总分(29.48±21.21分)明显低于治疗前(52.95±24.30分)(P<0.01);GRBAS评分中总嘶哑度G(0.67±0.76)明显低于训练前(1.88±1.05)(P<0.01),粗糙声R(0.52±0.58)明显低于训练前(1.36±0.55)(P<0.01);治疗后动态喉镜检查患者声带闭合、运动的对称性、粘膜波、振动规律性均改善(P<0.01);3例患者声带小结完全消失,13例患者声带小结缩小,5例与治疗前比较无明显变化;最长发声时间也由治疗前的8.87±3.75秒变为治疗后的12.54±3.68秒(P<0.01);治疗后嗓音的频率微扰、振幅微扰、噪谐比(分别为0.18%±0.08%、2.10%±0.98%、0.0034±0.0022dB)均明显低于治疗前(分别为0.43%±0.31%、4.55%±1.80%、0.0184±0.028dB)(P<0.01或0.05)。结论嗓音训练对声带小结患者发声障碍有良好的治疗效果。     

嗓音训练治疗声门闭合不全所致功能性嗓音障碍的疗效分析

目的探讨嗓音训练对声门闭合不全的功能性嗓音障碍患者的疗效。方法对24例声门闭合不全的功能性嗓音障碍患者进行8周的嗓音训练,训练内容包括健康宣教、肌肉放松、喉部按摩、暖嗓、呼吸训练、嗓音训练和共鸣训练,训练前后对患者进行电子喉镜检查、GRBAS评估、嗓音障碍指数量表（VHI）评估、计算机嗓音声学分析,比较训练前后评估结果。结果24例患者训练后电子喉镜检查16例患者声门闭合良好（66.67%,16/24）,6例声门裂隙变小（25.00%,6/24）,2例声门裂隙无明显变化（8.33%,2/24）;GRBAS评分中总嘶哑度G(0.61±0.66)明显低于训练前(1.91±0.87)（P<0.05）,粗糙声Ｒ(0.51±0.58)明显低于训练前(1.41±0.52)（P<0.05）;VHI评分总分(29.21±21.02)分明显低于训练前的(52.35±23.45)分（P<0.05）;计算机嗓音声学分析最长发声时间（15.24±3.64）s比训练前（9.02±3.45）s明显延长（P<0.05）,基频微扰、最高基频、最低音强、嗓音障碍严重指数训练后分别为（0.21±0.08）%、（420.11±44.21）Hz、（54.21±3.20）dB、（1.62±0.82）比训练前的（0.92±0.12）%、（375.21±49.21）Hz、（56.81±3.42）dB、（0.21±1.02）有改善（P<0.05）。结论嗓音训练能改善声门闭合不全的功能性嗓音障碍患者的声门闭合及嗓音质量。     

鼻中隔偏曲及慢性鼻窦炎鼻息肉患者的精神心理状态调查

目的 初步调查鼻中隔偏曲(DNS)、慢性鼻窦炎鼻息肉(CRSwNP)患者的精神心理状况,观察其手术前后的心理变化。 方法 利用焦虑自评量表(SAS)和抑郁自评量表(SDS)评估44例CRSwNP、41例DNS、31例声带息肉患者(对照组)手术前后焦虑、抑郁症状。另取39例健康者作健康对照。 结果 术前各组的SAS和SDS评分依次为:健康组(36.74±10.39; 38.51±11.30)、对照组(38.52±10.99; 42.26±10.42)、CRSwNP组(42.00±13.54; 43.84±15.44)、DNS组(45.02±10.80; 48.32±11.21)。健康组、对照组与DNS组之间的SAS和SDS评分差异有统计学意义(P<0.01)。CRSwNP组和DNS组的术前、术后的SAS和SDS评分差异有统计学意义(P<0.05)。约1/3的DNS组和CRSwNP组的患者术后仍出现焦虑或抑郁症状。 结论 DNS、CRSwNP患者存在一定的焦虑、抑郁症状,术后其评分较术前改善,但约1/3的患者术后仍有焦虑、抑郁症状,必要时应给予心理干预。     

嗓音疾病自我评估特点及影响因素

目的 探讨嗓音障碍疾病嗓音障碍自我评估特点及影响因素.方法 对1766例嗓音障碍患者及120例健康对照者行嗓音障碍指数(voice handicap index,VHI)量表评估,并对其中227例嗓音治疗后效果进行评估.结果 各种嗓音疾病患者VHI评分均明显高于对照组(z值范围8.039～17.043,P值均为0.000).不同嗓音疾病患者之间评分也有差异,量表总分自高而低依次为痉挛性发音障碍、声带麻痹、功能性发音障碍、声带沟、声带良恶性肿瘤、声带囊肿、声带任克水肿、声带息肉、声带角化与慢性喉炎、声带小结.痉挛性发音障碍组情感部分评分最高,其次为功能性发音障碍,而其他组生理部分评分均高于功能及情感评分.嗓音治疗后患者量表评分显著下降,术前术后VHI量表总评分差异有统计学意义(P值均<0.05).不同教育程度、年龄分组间量表总分差异有统计学意义(F值范围8.701～27.371,P值均为0.000),受教育程度越高,VHI评分越高;少年组VHI的各项最低,青年组最高,之后随年龄增长VHI逐渐下降.结论 VHI量表评估作为嗓音疾病严重程度及治疗效果评估的有益补充,可以从患者角度通过生理、机能及情感三方面综合评估嗓音障碍对日常生活影响及治疗前后变化,但具有一定主观性,可能受到教育程度及年龄因素影响.     

嗓音障碍指数对嗓音外科手术效果评估的价值

目的运用改良中文嗓音障碍指数量表,结合客观检查手段,评估嗓音障碍指数对嗓音疾病患者临床疗效分析的价值。方法 50例嗓音疾病患者手术前后分别进行自我评估、声学分析和喉镜检查。自我评估采用嗓音障碍指数(voice handicap index,VHI)量表中文版,包括功能(F)、生理(P)、情感(E)三方面评分,其总和记为T,其中,P+F=TvH;通过Dr.Speech嗓音分析软件对患者的嗓音样本进行声学分析,观察基频微扰(jitter)、振幅微扰(shimmer)、标准化噪声能量(normalized noise energy,NNE)三个指标。纤维喉镜检查主要观察声带闭合情况,记为C。结果 VHI量表中剔除了情感(E)方面后的嗓音自我评估分数,F、P、TvH之间的相关性良好,F、P、TvH与jit-ter、shimmer、NNE之间有良好的相关性,声带闭合程度(C)与VHI量表中的F、P、TvH以及jitter、shimmer、NNE之间有良好的相关性。结论改良的中文VHI量表,可有效地评估嗓音疾病严重程度及临床疗效,有较高的临床应用价值。     

强化自我护理对喉镜辅助声带息肉切除术后患者嗓音恢复及心理情绪的影响

目的 研究强化自我护理对喉镜辅助声带息肉切除术后患者嗓音及心理情绪的影响。 方法 选取2016年3月~2018年3月接受喉镜辅助声带息肉切除术治疗的患者94例为研究对象,将其按随机数字表法分成研究组与对照组各47例。对照组予以常规护理干预,研究组则予以强化自我护理干预。比较两组嗓音恢复情况,干预前后汉密尔顿焦虑量表(HAMA)、数字分级法(NRS)及生存质量测定量表(QOL)评分变化。 结果 研究组基频微扰、振幅围绕、自主发音能力比对照组低(t分别为5.181、3.355、11.017,P分别为0.001、<0.001、<0.001),而声音障碍指数比对照组高(t=4.550, P<0.001)。干预后研究组与对照组HAMA评分比干预前低(t分别为15.069、8.539, P均<0.001),且研究组比对照组低(t=6.935, P<0.001)。干预后研究组与对照组NRS评分比干预前低(t分别为4.788、2.535, P均<0.001),且研究组比对照组低(t=2.548, P=0.013)。干预后研究组与对照组QOL评分比干预前高(t分别为7.292、2.671, P分别为0.000、0.009),且研究组比对照组高(t=4.698, P<0.001)。 结论 强化自我护理有助于喉镜辅助声带息肉切除术患者嗓音的恢复,同时降低HAMA、NRS评分,提高QOL评分。     

阿克森疗法对声带息肉术后嗓音恢复的疗效探讨

目的 观察阿克森疗法对声带息肉术后嗓音功能恢复的临床效果.方法 经电子喉镜检查并在支撑喉镜下显微镜术后病理组织学检查结果证实为声带息肉患者60例,按随机数字表法随机将病例分为2组,治疗组在术后行常规护理的基础上加阿克森疗法进行嗓音恢复治疗;对照组在术后仅行常规护理治疗.随访1年后,有完整嗓音资料的治疗组18例,对照组20例,将对两组在3个月及1年后均行嗓音障碍指数(VHI)评估.结果 治疗组和对照组在3个月和1年的有效率差异均有统计学意义(P<0.05),有效率比较差异随时间延长有正相关性.结论 阿克森疗法对声带息肉术后嗓音功能恢复疗效确切并且方便, 适合在声带息肉术后恢复中推广阿克森疗法以防止复发.     

甲状舌管囊肿术后嗓音分析

目的探讨甲状舌管囊肿(TDC)患者手术前后的嗓音变化特点。方法选取2018年1月—2019年12月行TDC切除术的患者49例为研究对象，其中男24例，女25例，年龄为22~65岁，平均年龄为(41.55±11.78) 岁。对患者术前，术后1周及术后6个月分别行嗓音障碍指数（VHI）和GRBAS的主观评估、嗓音声学分析的客观检测以及频闪喉镜检查，比较手术前后的评估结果。结果①VHI的评估：女性患者的情感（E）评分在术后1周较术前显著性差异（P<0.05），术后6个月与术前差异不明显，而其功能（F）和生理（P）评分较术前无明显差异；男性患者手术前后的VHI各评分均无显著性差异；②GRBAS的评估：女性患者的气息度（B）和无力度（A）评分在术后1周较术前差异显著（P<0.05），术后6个月同术前差异不大，而其总分（G），粗糙度（R）和紧张度（S）评分无显著性差异；男性患者手术前后的GRBAS各评分均无显著性差异；③嗓音声学分析：男性及女性患者的基频（F0）和最长发声时间（MPT）在术后1周均较术前差异显著（P<0.05），术后6个月同术前差异不明显；而其基频微扰（jitter）和振幅微扰（shimmer）无显著性差异。结论TDC患者手术后会出现嗓音评估指标的一过性改变，及早行嗓音评估、发音训练或心理干预，有利于患者的嗓音康复。     

Voice handicap evaluation after supracricoid partial laryngectomy

The importance of patient self-impressions has been emphasized in determining the success of cancer treatment. The supracricoid partial laryngectomy (SCPL) is recognized as a suitable procedure for the treatment of T1b and T2 glottic carcinoma. The aim of this surgical procedure is the preservation of a physiologic phonation with optimal oncologic control. METHOD: Measurements included Voice handicap Index (VHI), Voice Related Quality of'Life (VRQL), subjective (GRBAS) and objective analysis. Objectives: evaluate voice problems after SCPL, provide correlations between patients' daily activities, VHI, and subjective evaluation of the dysphonia. PATIENTS: 53 patients were assessed more than 1 year after SCPL. 26 patients, less than 60 years of age and professionally active were included. The mean age was 48 years (43 to 59 years). Eleven patients had professional activities in the communications industry requiring a compulsory daily use of their voices. RESULTS: 57.6% of the active patients underwent a cessation or an adaptation of their professional activities. The mean VHI was 52.22. It was respectively 36.3, 50.03 and 52.42 according to the grade 1, 2, 3 of dysphonia. Correlations between VHI and the time laps since intervention (p: 0.047). discontinuation of professional activities (p: 0.037), and grade of dysphonia (p: 0.049) were found. CONCLUSION: VHI allows an evaluation of the voice problems after SCPL. A significant impact on voice is reported after SCPL and may influence the patient's life, with potential disturbance of their professional activities. Potential post surgical voice impact must be considered when the therapeutic options are discussed.     

Function preservation using transoral laser surgery for T2–T3 glottic cancer: oncologic, vocal, and swallowing outcomes

Aim of this study was to retrospectively analyze oncologic and functional results of a cohort of T2 and selected T3 glottic tumors treated by transoral laser surgery (TLS). Eighty-nine patients affected by T2 and T3 glottic tumors were treated by TLS from 2005 to 2010 at an academic institution by Type V cordectomies using an “en bloc” or, more frequently, a “piece-meal” technique depending on a number of variables. Kaplan–Meier curves were used to evaluate 5-year overall, disease-specific survivals, local control with laser, and organ preservation rates. Univariate analysis of the impact of different variables was performed. At least 1 year after surgery, we examined: subjective voice evaluation by voice handicap index (VHI), perceptive analysis by GRBAS scale, objective measurements with multidimensional voice program (MDVP), swallowing assessment with the M.D. Anderson Dysphagia Inventory (MDADI), videonasal endoscopic evaluation of swallowing (VEES), and videofluoroscopy (VFS). Fifty-nine patients were pT2 and 30 pT3. The 5-year overall, disease-specific survivals, local control with laser, and organ preservation rates were 92.4, 98.7, 68.5, and 82.1 %, respectively. VHI mean score was 20 (mild dysphonia). Mild and moderate dysphonias were detected by GRBAS in 82 and 18 % of patients, respectively. Mean values of Jitter, Shimmer, and noise-to-harmonic ratio by MDVP resulted 7.87 %, 24.8 %, and 0.37, respectively. Mean value of MDADI was 95.75. Only 2 % of patients at VEES and 4 % at VFS showed tracheal aspiration. Our results highlight that T2 and selected T3 glottic tumors treated by TLS have favorable oncologic and functional outcomes.     

Factors predicting patient perception of dysphonia caused by benign vocal fold lesions

OBJECTIVES/HYPOTHESIS: To assess factors that may be predictive of patient perception of dysphonia severity, as quantified by the Voice Handicap Index (VHI) score. We hypothesize that 1) level of vocal demand; 2) auditory-perceptual evaluation of dysphonia severity; and 3) vocal function, as defined by phonatory glottal closure and mucosal wave vibration, are the most significant predictors of VHI score. STUDY DESIGN:: Retrospective review of 100 patients with benign vocal fold lesions. METHODS: Variables assessed for predictive value to VHI score are level of vocal demands, auditory-perceptual evaluation of dysphonia severity, integrity of mucosal wave vibration and phonatory glottal closure, lesion type, duration of current complaint, smoking, age, and sex. Harmonic to noise ratio was assessed in a subset of 50 patients. RESULTS: Patients with routine voice use had significantly lower VHI scores than those with more intensive (nonsinging/acting) vocal demands. Patients who quit smoking had greater VHI scores than those who currently smoke or never started. Patients with long-standing dysphonia tended to have lower VHI scores than those with shorter duration vocal complaints. Auditory-perceptual assessment of dysphonia severity and harmonic to noise ratio were weak predictors of VHI score. Age, sex, lesion type, phonatory glottal closure, and mucosal wave vibration were not significant predictors of VHI score. CONCLUSIONS: Patient perception of dysphonia severity is independent of many factors commonly assessed during the evaluation of voice disorders. It appears to be an important independent element in the assessment of the effect of a benign vocal fold lesion and critical to therapeutic decision-making.     

Vocal outcome after endoscopic thyroarytenoid myoneurectomy in patients with adductor spasmodic dysphonia

Spasmodic dysphonia (SD) remains one of the most difficult of laryngeal pathologies to treat. With limited role for speech therapy, various surgical modalities have been tried with various success rates. The objective of the study is to report the results of vocal outcome after thyroarytenoid myoneurectomy in patients of adductor spasmodic dysphonia (ASD). 15 patients of ASD were selected. GRBAS, and voice handicap index (VHI) were used for perceptual evaluation of voice. Thyroarytenoid myoneurectomy was performed by vaporizing the muscular layer of the vocal fold with CO₂ laser, at an intensity of 6 W with 1.2 mm diameter in scanner mode. Voice analysis was repeated at 12, 24 and 48 months follow-up. Preoperative GRBAS scores and VHI score of all the patients were poor. At 12 months 12/15 (80 %) patients having strain score of 0. There was marked improvement in VHI scores at 6 months. 10/15 (67 %) patients have been followed up for 24 months. 5/10 (50 %) patients have strain (S) value of 0. VHI scoring of 5/10 (50 %) patients was <30. Two of the four patients completed 48 months follow-up had a strain (S) value of 0, one patient has strain value of 1 and one patient had strain value of 2. 2/4 patients had VHI score of <30; one patient had that of 40. Trans-oral CO₂ laser thyroarytenoid myoneurectomy shows significant long-term improvement in voice quality in terms of reduced speech brakes, effort and strain in voice.     

The correlation between subjective and objective voice evaluation in organic and functional larynx disorders

The aim of this research is to develop and introduce into phoniatric diagnostic procedures the complex methodology of vocal function assessment, on the basis of comparison of subjective and objective voice estimation. The set of complex voice evaluation ought to include perceptual examination of the voice quality with quantitative GRBAS scale as a subjective method, vocal folds vibrations in videostroboscopy as a quasi-objective method and acoustic voice estimation in Multi Dimensional Voice Program (MDVP) as an objective method. The basic assumption of this report is to prove correlation existence for vocal folds vibration quality in videostroboscopy, parameters describing acoustic wave generating by vibration system in larynx (MDVP) and perceptual subjective voice assessment (GRBAS scale) in organic and functional voice disorders. Research was conducted on 100 subjects (65 with organic and 35 with functional voice disorder), aged 7-74 years randomly chosen from population of patients treated at the Department of Phoniatrics and Audiology, Karol Marcinkowski University School of Medical Sciences in Poznań in 1996-2001 and 60 subjects as a control group without any voice disorders according to phoniatric examination. The research methodology include perceptual voice evaluation based on Japanese (Hirano) GRBAS scale adapted to Polish language, in scale 0 to 3 as well as the vibrations of vocal folds in videostroboscopy with attempt at quantification (scale 1 to 3) of selected measure and for acoustic analysis of Multi Dimensional Voice Program (MDVP) for 17 estimated parameters. Due to results and statistic analysis the own, new scale of dysphonia severity was introduced.     

早期嗓音训练对改善甲状腺术后声带麻痹患者嗓音质量的疗效观察

目的 探讨早期发声训练对改善甲状腺术后声带麻痹患者嗓音质量的效果.方法 选取西安交通大学第一附属医院耳鼻咽喉头颈外科甲状腺术后声带麻痹的48例患者为研究对象,随机分为实验组及对照组(各24例).实验组自术后1周开始进行系统嗓音训练,对照组不进行干预.对两组术后1周、12周及24周的嗓音主客观评估及频闪喉镜评估数据进行对...     

Factors predicting Voice Handicap Index

ObjectiveTo assess factors that may be predictive of patient perception of dysphonia severity, as quantified by the Voice Handicap Index (VHI) score.Material and methodsA prospective study is carried out in 81 voice samples from patients diagnosed with benign vocal fold lesions. Variables assessed for predictive value to VHI score are maximum fonation time, narrow band spectrogram, jitter, shimmer, HNR, NNE, F0 and the auditory perceptual evaluation of severity of dysphonia GRABS.ResultsHNR, F0 and B and S parameters of GRABS were predictors of total VHI score, functional and emotional subscales. No parameter was found to predict the physical subscale.ConclusionsVHI score is correlated with the perceived breathy voice and its acoustic attributes, such as signal-to-noise ratio. In other studies, patient perception of dysphonia is independent of many factors commonly assessed during the evaluation of voice disorders. It is reasonable to assume that the severity of glottic gap caused by benign vocal folds lesions is related to a low signal-to-noise ratio and the breathy phonation as its perceptual correlate. The physical subscale appears to be an independent element in the assessment of the patient perception of dysphonia.     

Long-term vocal functional results after glottectomy: a multi-dimensional analysis

Horizontal glottectomy (HG) is an efficient surgical procedure for the treatment of selected laryngeal carcinoma. The aim of this study was to verify the long-term voice results in a group of HG subjects. The study involved 16 subjects who had undergone HG at least 1 year before. Each subject underwent laryngoscopy and his/her voice was perceptually rated using the GRBAS (grade, roughness, breathiness, asthenicity, strain) scale; the other objective examinations included maximum phonation time (MPT), spectrography, and perturbation analysis. Finally, all of the subjects assessed their own voice using the voice handicap index (VHI). The endoscopic examinations showed good arytenoid mobility and antero-posterior valving of the arytenoid-epiglottal-ventricular band complex, whereas vibration of the neoglottis was more severely impaired. The mean GRBAS values were, respectively, 2.7, 1.9, 1.9, 0.9 and 0.7; the mean MPT was 8.2 s. The Yanagihara score of the voice spectrograms was 4 in all cases; perturbation analysis revealed the following mean values: fundamental frequency = 147; Jitter% = 6.5; Shimmer% = 13.9; and noise-to-harmonic ratio = 0.76. The mean VHI value was 35.8. Objective and subjective data showed a dysphonic voice after HG, whereas the self-assessment results revealed a low degree of perceived disability, suggesting that oral communication was well preserved.     

客观嗓音分析比较CO2激光术与传统剥脱术治疗声带白斑患者的疗效

目的 运用客观嗓音分析比较CO₂激光术与传统剥脱术治疗声带白斑的疗效。 方法 回顾性分析2018年10月至2019年5月住院治疗的确诊为声带白斑患者病历资料,筛选出行CO₂和传统剥脱术患者,CO₂治疗组、传统剥脱术治疗组,对比两组患者手术时间、术中出血量、术后有效率,分别于术后2周、1个月、2个月分析统计两组患者嗓音障碍指数(VHI),采用xion divas的嗓音分析软件,检测手术前及手术后2周、1个月、2个月基频微扰(Jitter)、振幅微扰(Shimmer)、最低音强(SPLmin)、最高基频(F0max)、基频(F0)、最长声音持续时间(MPT)、嗓音障碍指数(DSI)。 结果 CO₂治疗组患者手术时间更短,术中出血量更少;CO₂治疗组有效率高于传统剥脱术治疗组,疗效更佳;两组患者术后1个月、2个月VHI指数均较术前降低,且CO₂治疗组VHI指数低于传统剥脱术治疗组;两组患者治疗后基频微扰、振幅微扰、最低音强均低于治疗前,基频、最长声音持续时间、嗓音障碍指数高于治疗前。 结论 采用CO₂激光术治疗声带白斑较传统的剥脱术疗效更佳,能显著改善患者嗓音。