Eruption cyst in the adult--a case report

A case of eruption cyst in the right maxilla of a 40-year-old female is reported.     

Glandular odontogenic cyst: a report of four cases

A glandular odontogenic cyst is a developmental cyst that is a clinically rare and histopathologically unusual type of odontogenic cyst. In this article, we describe four cases of glandular odontogenic cyst. Glandular odontogenic cyst was defined as a well-defined unilocular lesion on panoramic radiographs and multidetector computed tomography. Furthermore, the connection of the cyst to the periodontal tissue was one of the common features of the four cases. The results of the present study indicate the clinical and imaging features of glandular odontogenic cyst.     

Mandibular buccal bifurcation cyst: enucleation without extraction

The mandibular buccal bifurcation cyst (MBBC) is a cystic lesion, which occurs on the buccal surface of the permanent mandibular first molar in children around 6-8 years old. Treatment of the cyst has been controversial: extraction of the involved tooth and enucleation of the cyst, or only enucleation, without extraction. The aim of this article is to familiarize oral and maxillofacial surgeons with this entity and the appropriate treatment approach. The diagnostic features of MBBC are described and the treatment approach in five patients with a total of seven cysts is presented. Two cases were identified in identical twins. Enucleation of the cyst without extraction of the involved tooth is the treatment of choice when the available data and experience in treating MBBC are considered.     

Massive residual dental cyst: Case report

A case report is presented of a massive residual dental cyst that involved over half an edentulous mandible. Presentation, diagnosis and management of the massive cyst is discussed.     

Massive residual dental cyst: Case report

A case report is presented of a massive residual dental cyst that involved over half an edentulous mandible. Presentation, diagnosis and management of the massive cyst is discussed.     

囊肿塞子在颌骨囊肿开窗减压术中的应用

目的 探讨囊肿塞子在颌骨囊肿开窗减压术中的应用价值。 方法 选取2008年至今巨大颌骨囊肿和替牙期囊肿患者共122例,行开窗减压术后制作125件囊肿塞子（1例多发囊肿）,观察效果。 结果 本组病例中100例患者囊腔在1~2年内闭合,包含23例9~12岁儿童,22例患者遗留一小囊腔,需二次手术,随访2年无一例复发。下颌愈合时间较上颌愈合时间短,所有混合牙列期患者恒牙均正常萌出,膨出的面型恢复正常。 结论 颌骨囊肿开窗减压术后佩戴囊肿塞子可以有效地阻止食物进入囊腔,引流出囊液。     

Oral alimentary tract cyst

A cyst in the floor of the mouth of a 2-yr-old boy was characterized by smooth muscle tissue with an overlying epithelial lining of varying morphology including gastric mucosa. The combination of smooth muscle with a variety of epithelial linings argues against the "misplaced anlage" histogenesis.     

颈上部支气管源性囊肿1例报告及文献复习

报告1例颈上部支气管源性囊肿,结合文献资料分析其临床表现、影像学、细胞学及病理学特征,为临床诊断及鉴别诊断提供参考。支气管源性囊肿发生在颈上部者非常少见,其症状和体征与常见的颈部肿物相似,鉴别较为困难,术前易误诊为鳃裂囊肿、淋巴管畸形、舌下腺囊肿等。临床上需完善检查、综合判断、妥善处理。     

Ameloblastomatous calcifying odontogenic cyst: a rare histologic variant

Calcifying odontogenic cyst (COC) is an uncommon developmental odontogenic cyst first described by Gorlin in 1962. It is considered as extremely rare and accounts for only 1% of jaw cysts reported. Because of its diverse histopathology, there has always been confusion about its nature as a cyst, neoplasm or hamartoma. Several subclassifications have been proposed. Here, we present a case of calcifying odontogenic cyst with ameloblastic proliferation - an extremely rare histologic variant. The classical histologic features of the lining epithelium in the form of cords and presence of characteristic ghost cells were seen along with ameloblastomatous proliferations. Ameloblastomatous COC microscopically resembles unicystic ameloblastoma except for the ghost cells and calcifications within the proliferative epithelium. The nature of the COC is controversial. The case is presented here for its rarity, and difference between ameloblastomatous COC and ameloblastoma ex COC has been emphasized.     

Odontogenic cyst with verrucous proliferation

An unusual case of an odontogenic cyst with verrucous proliferation is described in a 13-year-old girl. This histologically distinctive odontogenic cyst variant does not appear to have been reported previously. The cyst was characterised by a series of verrucous projections in the lumen with hypergranulosis and cells resembling koilocytes, raising the possibility of a viral aetiology. However, no evidence of human papillomavirus (HPV) was found using immunohistochemistry and polymerase chain reaction (PCR) amplification.     

Gingival cyst of the adult,lateral periodontal cyst,and botryoid odontogenic cyst: An updated systematic review

The aim of the present review was to integrate the available data published on gingival cyst of the adult (GCA), lateral periodontal cyst (LPC), and botryoid odontogenic cyst (BOC) into a comprehensive analysis of their clinical/radiological features. An electronic search was undertaken in July/2017. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm the diagnosis. A total of 146 publications (157 GCAs, 213 LPCs, 96 BOCs) were included. GCA and LPC presented highest prevalence in the sixth/fifth decades; BOC in the sixth/seventh decades. LPCs were larger lesions than GCAs and GCAs appeared at an older age than LPC. There was no statistically significant difference between them for other factors (location, symptoms, recurrence, follow‐up time). In comparison with LPC, BOC lesions were larger, appeared more often in mandible and in older subjects, had more often a multilocular appearance, and presented a higher recurrence rate. Recurrence rates: GCA (3.2%), LPC (2.4%), BOC (21.7%). No factor seems to influence the recurrence rate of GCA or LPC. Multilocular radiological appearance seems to affect the recurrence rate of BOCs. Conservative surgical approaches seem to be enough for GCA/LPC. BOC presents a more aggressive behavior than GCA/LPC. Therefore, treatment of this lesion might involve some kind of adjunctive therapy after enucleation.     

耳后区进路切除第二鳃裂囊肿8例分析

目的：探讨耳后区进路切除第二鳃裂囊肿的可行性及美容效果。方法：8例第二鳃裂囊肿患者（其中男3例,女5例）,采用耳后区切口进路作病变切除术。结果：全部病变被完整切除,切口愈合良好,无耳大神经和面神经下颌缘支损伤。经平均14.5个月随访,病变无复发,瘢痕隐蔽。结论：耳后区进路切除第二鳃裂囊肿方法可行,并可获得理想的美容效果。     

The polymorphous odontogenic cyst

Over the years there have been sporadic reports of unusual cystic lesions of the jaws, not readily classified under conventional headings but which have been variously diagnosed as median-mandibular. glandular, sialo-odontogenic or botryoid odontogenic cyst. We present five cases which do not fit into other categories of odontogenic cyst, two of which have recurred within a few years of conservative treatment. This paper aims to alert clinicians to the propensity for regrowth of these cysts, proposes the term polymorphous odontogenic cyst for these lesions, to encompass their varied histological appearances and discusses their distinction from other cyst types with mucous and papillary formations in epithelium.     

Cytokine and chemokine levels in radicular and residual cyst fluids

Background:  Cytokines were thought to play an important role for the expansion of odontogenic cysts. The purpose of this study was to evaluate the cytokine and chemokine levels of radicular and residual cyst fluids.
Methods:  Cyst fluids were aspirated from 21 patients (11 radicular and 10 residual cysts) and the levels of interleukin-1 alpha (IL-1α), tumor necrosis factor-alpha (TNF-α), monocyte chemotactic protein-1 (MCP-1), and regulated upon activation normal T cell expressed and secreted (RANTES) were determined by ELISA using commercially available kits.
Results:  Both radicular and residual cyst fluids contained IL-1α, TNF-α, MCP-1, and RANTES, concentrations of which were significantly higher in the radicular cyst fluids than those in the residual cysts ( P  < 0.001 for IL-1α, TNF-α, and RANTES; P  < 0.01 for MCP-1). Compared to the other mediators, the concentration of IL-1α was found to be highest in both of the cyst fluids. In addition, positive correlations were found between IL-1α, TNF-α, MCP-1, and RANTES in radicular and residual cyst fluids.
Conclusion:  If the radicular cyst is inadvertently left behind following tooth extraction, some degree of inflammation may carry on. Residual cysts, although to a lesser extend than radicular cysts, have the potential to expand.     

The lateral periodontal cyst: an update

Lateral periodontal cysts account for 0.8% of all jaw cysts seen in our department. Published reports have indicated that they occur most frequently in the 5th to 7th decades, that there is a male preponderance and that they are located mainly in the mandibular canine-premolar region. In our own series of 20 cases, 10 were found in the anterior maxilla. We have distinguished unicystic and multicystic (including botryoid) varieties. They were lined predominantly or exclusively by thin reduced enamel epithelium-like tissue which contained many clear cells and epithelial thickenings referred to as plaques. Glycogen was present in the epithelium of two-thirds of our cases although not exclusively in the clear cells, many of which showed no positivity. Two of our examples of the botryoid variety were different histologically, being lined predominantly by non-keratinizing stratified squamous epithelium with crowded and pyknotic nuclei and no clear cells. One case contained melanin while another showed epithelial crypt formation and superficial palisaded low columnar cells as seen in the glandular odontogenic cyst. This raised the question of whether the latter may form part of the clinicopathologic spectrum of lateral periodontal cyst. The histogenesis of lateral periodontal cysts is uncertain but we favour origin from reduced enamel epithelium.     

Dermoid cyst of the parotid gland

A dermoid cyst occurring within the parotid gland of a 37-year-old Chinese man is reported. The diagnostic difficulties, histopathological features and pathogenesis are considered.     

Traumatic bone cyst: case report

Abstract The traumatic bone cyst is a lesion whose aetiology and pathogenesis have not been conclusively established. There are several theories and names for this lesion and various forms of management have been reported in the literature. This report outlines the clinical and radiographic findings associated with a case of a traumatic bone cyst. Laboratory investigations were also carried out and their findings are reported. This case was treated jointly by the endodontic and oral surgery departments of an institution and demonstrates the need for close follow-up from both departments. In particular, the endodontic aspects of monitoring the pulp status of teeth in the region of such a bone lesion are emphasised.     

口腔淋巴上皮囊肿3例报道

对3例口腔淋巴上皮囊肿进行临床病理分析,该囊肿的好发部位为口底,临床上常诊断为黏液腺囊肿等囊性疾病。镜下观察淋巴上皮囊肿以囊壁内衬复层鳞状上皮及纤维囊壁存在大量淋巴样组织为其特点。目前认为。口腔淋巴上皮囊肿可能来源于舌下腺或小唾液腺分泌管。由于慢性刺激,分泌管上皮发生鳞状化生,化生上皮的腔面细胞脱落后引起周围淋巴细胞浸润,表现为淋巴上皮囊肿。本文结合文献进行讨论,为类似病例的预防和诊断提供参考,为临床诊断和治疗提供借鉴。     

Odontogenic cyst induction by periapical infection in rats

The purpose of this study was to test the hypothesis that Odontogenic cysts can be induced by periapical infection. Pulp extirpation and reaming beyond the root apices were performed in 53 lower first molars in 27 Sprague-Dawley rats. The cavities were left open to allow continuous contamination by oral bacteria. Animals were killed at 6 and more than 8 months after operation. Odontogenic cysts were found in association with 8/53 teeth in 6 animals. Historically, cysts were observed around the lower incisors below the first molars. The cyst wall consisted of fibrous connective tissue with inflammation and was lined with keratinized squamous epithelium. The cyst cavity contained a mass of keratin and necrotic debris. These results support the hypothesis that inflammatory stimulation from the apices can cause cystic changes in the enamel epithelium of underlying teeth.     

Glandular odontogenic cyst: analysis of cytokeratin expression and clinicopathological features

The glandular odontogenic cyst (GOC) is a rare odontogenic cyst which is still controversial in regard to classification, terminology, and origin. The first Japanese case of GOC is reported. Immunohistochemical examination for expression of cytokeratins and epithelial membrane antigen by monoclonal antibodies suggested that the lining epithelium was of odontogenic origin with metaplastic mucus-laden cells. We have reviewed the literature and compared the clinicopathological findings of the reported case of GOC with those of botryoid odontogenic cysts (BOC). The anatomical location, age range, and sex of GOC cases were very similar to those of BOC. GOC appears to be a multilocular and mucoe-pidermoid variant of non-keratinizing odontogenic cysts, which also includes BOC. GOC should be separated from the other types of odontogenic cyst and central mucoepidermoid tumours of salivary gland origin.