Fine needle aspiration biopsy cytology in diagnosis of salivary gland tumours

Fine needle aspiration biopsy cytology of salivary gland tumours was performed in 97 patients. Histological confirmation was available in all cases except 9 cases of sialo-adenitis which responded to antibiotics. Accuracy of cytological diagnosis in exact categorisation of benign and malignant tumours was 93.7% and 91.1% respectively. False negative was 4.1%. The overall accuracy was 95.8%. There was no false positive report. Exact classification of tumour was made in 94.1% cases, ie, 80 out of 85 tumours. No complication was encountered in this procedure.     

Fine needle aspiration cytology of thyroid nodules--evaluation of its role in diagnosis and management

Thyroid swelling is a common problem in India. Early and systematic evaluation of a nodular thyroid swelling is necessary as it is a frequent presentation of thyroid neoplasia. The objective of this study was to evaluate the efficacy of fine needle aspiration cytology (FNAC) in diagnosis and management of thyroid nodules. With the help of statistical parameters, the significance of FNAC in surgical decision making protocol has been evaluated. A comparison between final histopathological findings with initial FNAC findings is done and sensitivity, specificity, positive and negative predictive value and accuracy of FNAC is calculated and compared to already existing studies. A total of 120 cases of nodular thyroid were included, among which 12 cases were excluded from statistical analysis as they were managed conservatively. Total operated cases were 108 and study period was from November 2006 to October 2009. Analysis revealed sensitivity, specificity and accuracy of FNAC as 90%, 84.6% and 86.1% respectively. There were 12 FNAC false positive cases among which 9 were follicular neoplasm and 3 were Hurthle cell neoplasm which ultimately came as benign in histopathology. Only 3 cases of adenomatous nodule as per FNAC report proved to be papillary carcinoma on histology (ie, false negative). This study concludes that FNAC is an important diagnostic tool in early and cost effective evaluation of thyroid nodules. It helps in decision making for appropriate surgical/non-surgical management.     

细针吸取细胞学在乳腺疾病诊断中的意义

目的:探讨细针吸取细胞学(fine neelde aspiration cytology,FNAC)在诊断乳腺疾病中的价值.方法:我院2003年10月～2008年5月门诊和住院的乳腺疾病患者362例,其中201例经病理组织学对照.结果:201例经病理组织学对照,良性肿瘤136例,恶性肿瘤65例,总符合率为97.50%,细胞学与病理组织学诊断完全一致的占91.54%,定性(良、恶性)正确而组织学类型不一致的占5.79%,良、恶性误诊率为2.49%.结论:FNAC对乳腺疾病的诊断有独到的临床价值.     

Fine needle aspiration biopsy cytology in diagnosis of cervical lymphadenopathies

Four hundred and forty-four patients with cervical lymphadenopathies without any consideration for age and sex were subjected to fine needle aspiration biopsy cytology. The results were compared with those of histological sections. In tuberculous lymphadenitis, pyogenic lymphadenitis, Hodgkin's disease and leukaemic infiltration of lymph nodes 100% correct diagnosis was made; it was 98.4% in metastatic carcinoma, 97% in non-specific lymphadenitis and 92.3% in non-Hodgkin lymphoma. An overall 96.2% correct diagnosis was made by fine needle aspiration biopsy cytology technique.     

肺针吸细胞病理学在肺部疾病诊断中的应用

目的:探讨肺部穿刺针吸细胞学检查的诊断和应用。方法:对有组织学对比的1 343例经皮肺穿刺针吸组织进行细胞学涂片与组织学切片比较分析。结果:涂片阳性率57%,涂片对肺部恶性肿瘤分型符合率66%。结论:细胞学的诊断阳性率较高,但分型率较低,与组织学结合,能提高肺癌的术前诊断准确性。     

Role of fine needle aspiration cytology in the diagnosis of pulmonary lesions

Fine needle aspiration cytology (FNAC) is a rapid, reliable and cost-effective method in the diagnosis of lung lesions. Cells are collected from the lesions usually under fluoroscopic or CT-guidance for cytological examination. Due to lack of these highly sophisticated radiologic imaging techniques in our institute we performed this test under X-Ray film guidance. This study was carried out in 59 patients, who underwent FNAC of lung lesions in the department of Pathology, Mymensingh Medical College, Bangladesh to find out the specimen adequacy and frequency of both benign and malignant lesions of the lungs in our areas. Out of 59 cases 54 were males and 5 were females with age ranged from 20 to 82 years. Adequate samples were obtained in 50 (84.75%) cases of which 35 (70%) were malignant, 10 (20%) were benign and 5 (10%) were suspicious for malignancy. Malignant lesions comprised of squamous cell carcinoma in 20 (57.14%), adenocarcinoma in 1(2.86%), large cell carcinoma in 8 (22.86%) and small cell carcinoma in 6 (17.14%) cases. All the benign lesions were inflammatory in nature, which included abscess in 6 (60%), tuberculosis in 3 (30%) and chronic non-specific inflammation in 1 (10%) case. Majority of the malignant lung lesions were encountered in the 6th decade of life. As the method is simple, rapid, cost-effective and without major complications, so it can be practiced in any centres in our country where specialised radiologists and pathologists are available.     

针吸检查在肺部疾病诊断中的价值

目的：探讨针吸细胞学检查（Fine Needle Aspiration cytology FNAC)在肺部病诊断中的临床实用价值。方法：回顾分析248例临床病例,并结合文献复习,结果：穿刺检查在肺部疾病诊断中阳 率显著高于普,纤维支气管镜检查（P＜0．005）,且结果可靠;穿刺检查与外科摘除活检联合检测可提高肺部疾病的诊断率,结论：对肺说疾病伴有浅表淋巴结肿大者应尽早作针吸检查,该项检查方法简单,快速,病人痛苦少,便于推广。     

隆胸术后并发症的针吸细胞学诊断

目的 探讨隆胸术后并发症的针吸细胞学特点、鉴别诊断及其在临床诊断中的意义.方法 收集我院经针吸细胞学检查诊断10例病例,对其临床表现及针吸细胞学特点进行分析、总结.结果 凝胶聚丙烯酰胺水凝胶假体植入者7例,其中有1例于凝胶假体植入术后一年针吸为乳腺癌；3例为自体脂肪注入,均有较特异的形态学特点.结论 针吸细胞学诊断隆胸术后并发症快速、损伤小、操作简便并且准确率高,可以为临床医生选择合理治疗方案提供重要依据.     

Computed tomography guided fine needle aspiration cytology in the diagnosis of thoracic lesions

Computed tomography (CT) allows the performance of fine needle aspiration cytology (FNAC) in situations in which ultrasound or conventional x-rays do not correctly visualise the lesion or the needle tract. Over an 18-month period 184 patients underwent CT-guided FNAC of thoracic lesions. Of these 140 patients presented with pulmonary parenchymal lesions, 18 with mediastinal lesions, 14 with pleural lesions and 12 with hilar lymphadenopathy. A categorical diagnosis was possible in 180 (98%) cases. In majority of the cases only one or two passes were required. Two cases developed pneumothorax and required chest drainage. It can be concluded from the present observations that FNAC under CT control is a useful and accurate diagnostic technique.     

Multiple lymphomatous polyposis and the role of fine needle aspiration cytology.

Multiple lymphomatous polyposis is an uncommon but distinctive form of gastrointestinal lymphoma. Clinical symptoms may closely resemble those of colorectal carcinoma and diagnostic confusion may result. The condition has a characteristic pathological appearance and immunophenotype which is important in allowing distinction from other less aggressive forms of gastrointestinal lymphoma. We report a case of this unusual condition in which the diagnosis was aided by fine needle aspiration cytology.     

Role of fine needle aspiration cytology in diagnosis of breast lumps.

Objective: The aim of this study is to find out the common causes of breast lump and to determine the sensitivity and specificity of FNAC of breast lump. Materials and methods: This is a retrospective study of FNAC of breast done in pathology department of NMCTH from January 2003 to December 2005. FNAC findings were correlated with data from histopathology records to determine the sensitivity and specificity of FNAC. Results: FNAC of breast constituted 16% of all the FNACs. Age group of the patients ranged from 17 to 56 years with mean of 32 years. Fibroadenoma was the most common diagnosis. Malignancy was diagnosed in only 6.6% of the cases. Histological correlation was done in 21 cases. Sensitivity and specificity of FNAC of breast was found to be 83.3% and 100% respectively. Conclusion: FNAC of breast is simple, cost effective and less traumatic method for diagnosis of breast lump. It is highly sensitive and specific also, and can reduce the needs for open biopsies. So FNAC should be used as a routine method for determining the nature of breast lumps. Key words: FNAC, breast lump, neoplasm.     

细针吸取细胞学检查在临床病理诊断中的应用

目的 探讨细针吸取细胞学检查在体表以及经体表可触及肿物的诊断价值.方法 对158例行细针吸取细胞学检查患者的结果与组织学诊断结果进行对照.结果 68例恶性肿瘤的敏感性为(63/68)92.6%,90例良性病变的特异性为(85/90)94.4%,148例获得正确诊断,10例病变虽未明确诊断,但均未因诊断意见不一致造成过度...     

Fine needle aspiration cytology diagnosis of a case of carotid body tumour

Carotid body tumour (CBT) is a paraganglioma arising from the chief cells of the carotid body, which is situated at the bifurcation of the common carotid artery. We describe the fine needle aspiration cytology findings of one such tumour in a 27-year-old man. The aspirate was haemorrhagic with clusters of round to oval cells showing moderate anisokaryosis. Delicate fibrous strands with spindle cells were observed within these clusters. Based on these cytologic findings and the location of the swelling, a diagnosis of CBT was made. The mass was excised and the diagnosis was confirmed on histopathological examination. Our case report adds to the existing literature on cytologic diagnosis of CBT, further attesting to its safety and accuracy.     

超声引导下针吸细胞学检查在甲状腺混合性结节微波消融术前的诊断价值

目的:探讨超声引导下针吸细胞学检查(ultrasonic guidance fine needle aspiration cytology,US-G FNAC)在甲状腺混合性回声结节(Thyroid mixed echo nodule)微波消融术前的诊断价值.方法:选取2018年8月～2019年8月于我院行微波消融术治...     

乳腺肿块细针吸取细胞学与术中冰冻切片诊断比较

目的：分析乳腺肿块细针吸取细胞学(FNAC)与术中冰冻切片诊断(IFSD)的不同特征，探索两者的临床应用价值。方法：对乳腺肿块205例分别进行FNAC和IFSD检查。结果：乳腺良性病变FNAC和IFSD的准确率分别为96．4％和98．6％，乳腺恶性肿瘤FNAC和IFSD的准确率分别为91．0％和97．0％。FNAC假阴性率为2．4％，无假阳性诊断；IFSD未出现假阴性和假阳性诊断。结论：乳腺肿块FNAC和IFSD检查是两种实用、可靠的诊断方法。