^99mTc（V）—DMSA及^99mTc—MIBI肺显像诊断原发性肺癌的应用研究

对３０例原发性肺癌患者分别应用＾９９ｍＴｃ（ｖ）－ＤＭＳＡ及＾９９ｍＴｃ－ＭＩＢＩ显像。结果表明：＾９９ｍＴｃ９Ｖ）－ＤＭＳＡ，＾９９ｍＴｃ－ＭＩＢＩ敏感度分别为９０％，７６．７％。两者结合显像阳性率为９６．７％。鳞状上皮细胞癌对＾９９ｍＴｃ（Ｖ）－ＤＭＳＡ及＾９９ｍＴｃ（Ｖ）－ＤＭＳＡ，＾９９ｍＴｃ－ＭＩＢＩ摄取程度比其它类型的肺癌高。     

18F-FDG PET全身显像与99mTc-MDP骨显像诊断肿瘤骨转移灶的对比研究

为评价＾１８Ｆ－ＦＤＧ ＰＥＴ全身显像对肿瘤骨转移的诊断价值,对５２例肿瘤患者同时进行＾１８Ｆ－ＦＤＧ ＰＥＴ显像及＾９９ｍＴｃ－ＭＤＰ骨显像,骨转移灶的最以组织病理、或ＣＴ、ＭＲＩ影像学检查和临床随访结果为依据。５２例患者共检出骨转移灶１０６处,骨显像诊断骨转移的灵敏度（８９．６％）高于ＰＥＴ（６３．２％）。ＰＥＴ对肋骨及头颅骨转移的检测灵敏度较低,且单纯应用ＰＥＴ定位存在困难。因而对＾１８Ｆ＝     

SPECT脑血流灌注显像应用于脑血管疾病

７０例脑血管疾病患者（脑梗塞、ＴＩＡ、ＶＢＩ）行＾９９ｍＴｃ－ＥＣＤ ＳＰＥＣＴ脑血流灌注显像，并与ＣＴ、ＭＲＩ对照，结果ＳＥＰＣＴ诊断脑血管病的阳性率为９０％。ＣＴ为８８．２％（４５／５１），ＭＲＩ为９０％（２７／３１）。脑梗塞５５例中５１例ｒＣＢＦ图像上出现血流灌注减低区，４例发现交叉性小脑神经机能失联络证。诊断ＴＩＡ、ＶＢＩ的阳性率为７５％。ＳＰＥＣＴｒＣＢＦ显像发现病灶较ＣＴ、ＭＲＩ多；可     

^153Sm—EDTMP治疗50例肿瘤性胃痛临床观察

５０例不同癌症患者用＾１５３Ｓｍ－ＥＤＴＭＰ治疗后７６％患者的骨痛有不程度的减轻，骨痛消失率达２０％。骨痛缓解时取１－２个月者为６０％。１０例患者＾９９ｍＴｃ－ＭＤＰ骨显像患／健侧值与＾１５３Ｓｍ－ＥＤＴＭＰ相隔１个月两个显像患／健侧值自身对照。     

^99mTc—DTPS和^99mTc—EC肾功能显像对高血压患者的肾功能估测

利用＾９９ｍＴｃ－ＤＰＴＡ和＾９９ｍＴｃ－ＥＣ分别观测了３２例和２４例高血压患者的肾功能显像；同时与２９例对照组作了比较。结果表明，原发性高血压患者的肾小球滤过率明显下降，其分肾ＧＦＥ之间无明显差别；肾血管性高血压患者ＧＦＲ不仅低于对照组和原发性高血压组，且患侧肾脏ＧＦＲ又低于健侧肾脏。     

^99mTc—MIBI显像鉴别甲状腺“冷”结节的性质

用＾９９ｍＴｃ－ＭＩＢＩ显像法对５６例经病理证实的甲状腺“冷”结节患者鉴别，结果血流丰富的共２２例，＾９９ｍＴｃ－ＭＩＢＩ显像Ｔ／ＮＴ比值，恶性病变中乳头状癌、滤泡状癌，髓样癌，未分化癌均与＾９９ｍＴｃＯ＾－５显像有非常显著性差异，而良性病变中仅腺瘤有显著性差异，其余均无显著性差异。     

亲肿瘤显像剂^99Tc^m（V）—DMSA显像对^153Sm—EDTMP治疗骨转移癌的疗效评价

使用亲肿瘤显像剂＾９９Ｔｃ＾ｍ（Ｖ）－ＤＭＳＡ,对１６例经＾１５３Ｓｍ－ＥＤＴＭＰ治疗２～８个疗程后的骨转移癌患者进行随访显像研究。结果表明,中轴骨转移灶的消失率为４８．１％,四枝骨转移灶消失率为４１．９％,总有骨转移灶消失率为４５．８％,＾９９Ｔｃ＾ｍ（Ｖ）－ＤＭＳＡ具有亲肿瘤特性和亲骨性,对于＾１５３Ｓｍ－ＥＤＴＭＰ治疗骨转移癌疗效的随访,具有理论上的可信性和客观性;对于＾１５３Ｓｍ－ＥＤＴＭ     

^99mTc—MIBI评价缺血／再灌注心肌活力的实验研究

应用＾９９ｍＴＣ－ＭＩＢＩ对家兔缺血／再灌注心肌细胞及线粒体代谢和活力进行了评价，将家兔ＬＡＤ阻断２０ｍｉｎ，３ｈ再灌主，于灌注后２－５ｍｉｎ静脉注射＾９９ｍＴｃ－ＭＩＢＩ，结果缺血３ｈ组缺血心肌再灌注早期（１０ｍｉｎ）晚期（３ｈ）相对放射性活度，心肌ＡＴＰ含量均明显低于缺前２０ｍｉｎ组，非缺血心肌和缺血２０ｍｉｎ心肌＾９９ｍＴｃ－ＭＩＢＩ亚细胞分布与ＳＤＨ活性呈显著正相关（ｒ＝０．８８，Ｐ〈０．     

~(99m)Tc(Ⅴ)-DMSA 及 ~(99m)Tc-MIBI 肺显像诊断原发性肺癌的应用研究

对３０例原发性肺癌患者分别应用９９ｍＴｃ（Ⅴ）－ＤＭＳＡ及９９ｍＴｃ－ＭＩＢＩ显像。结果表明：９９ｍＴｃ（Ⅴ）－ＤＭＳＡ、９９ｍＴｃ－ＭＩＢＩ敏感度分别为９０％、７６．７％。两者结合显像阳性率为９６．７％。鳞状上皮细胞癌对９９ｍＴｃ（Ⅴ）－ＤＭＳＡ及９９ｍＴｃ－ＭＩＢＩ摄取程度比其它类型的肺癌高。     

^99mTc—MIBI心肌灌注显像潘生丁试验一天法在冠心病诊断中的应用

介绍了对１６１例冠心病患者采用＾９９ｍＴｃ－ＭＩＢＩ心肌显像潘生丁试验一天法方案进行检测的结果，其中２０例与冠状动脉造影进行了对比观察。患者先作＾９９ｍＴｃ－ＭＩＢＩ静态平面与断层心肌显像，接着进行潘生丁试验，再于静脉注射＾９９ｍＴｃ－ＭＩＢＩ后１ｈ作平面与断层心肌显像。采用本方法诊断冠心病的灵敏度为９１％。其检测ＬＡＤ的灵敏度为８８％；诊断ＲＣＡ及Ｌｃｘ的灵敏度分别为８１％与７７％、特异性分别为     

Isospin Distribution of Fragments in Reaction ~(96)Ru ~(96)Ru, ~(96)Ru ~(96)Zr,~(96)Zr ~(96)Ru,and ~(96)Zr ~(96)Zr at Beam Energy 400 AMeV

The isospin distribution of particles and fragments in collisions 96Ru 96Ru, 96Ru 96Zr, 96Zr 96Ru, and 96Zr 96Zr at beam energy 400 AMeV is studied with isospin dependent QMD model. We find the rapidity distribution of difference between neutron-proton number in neutron rich nucleus-nucleus collisions at intermediate energies is sensitive to the isospin dependent part of nuclear potential. The study of the N/Z ratio of nucleons, light charged particles (LCP) and intermediate mass fragments (IMF) shows that the isospin dependent part of nuclear potential drives IMF to be more isospin symmetric and emitted nucleons to be more neutron rich. We also study the time evolution of the isospin distribution     

Investigation of production of medical ~(82)Sr and ~(68)Ge for ~(82)Sr/~(82)Rb and ~(68)Ge/~(68)Ga generators via proton accelerator

How to operate~(82)Sr/~(82)Rb and ~(68)Ge/~(68)Ga generators used in the positron emission tomography scan process is explained, and the importance of ~(82)Sr and ~(68)Ge radionuclides for these generators is revealed. To produce medical ~(82)Sr and ~(68)Ge by means of a proton accelerator in an irradiation time of 24 h, a proton beam current of250 l A, and an energy range E_(proton)= 100 →5 MeV, the cross sections and the neutron emission spectrum curves of(p,xn) reaction processes on Rb-85, Ga-69 and Ga-71 targets were calculated, and the activities and yields of the product were simulated for the reaction processes. Additionally, the integral yields of the reaction processes were determined via the calculated cross-sectional curves and the mass stopping power obtained from the X-PMSP program. Furthermore, based on the obtained results, the appropriate reaction processes for the production of ~(82)Sr and ~(68)Ge isotopes on Rb-85, Ga-69, and Ga-71 targets are discussed.     

Near-barrier Fusion Evaporation and Fission of ~(28)Si+~(174)Yb and ~(32)S+~(170)Er

<正>Heavy-ion induced fusion-fission reactions at energies around the Coulomb barrier have attracted much attention~([1-2]),due to many degrees of freedom involved in the interaction processes.It has been experimentally proved that the coupled interactions of some intrinsic motions and relative motion play a significant role in the process that     

Measurement of ~(25)Mg(~7Li,~6He)~(26)Al Angular Distribution

<正>In order to study the 58keV resonance in ~(25)Mg(p,γ)~(26)Al reaction,the measurement of the~(25)Mg(~7Li,~6 He)~(26) Al*_(6.364)reaction was carried out by using a 31.5 MeV ~7Li beam from the HI-13tandem accelerator,Beijing.The 200 enA 7Li beam impinged on ~(25)MgO,~(24)MgO and ~(12)C target,     

被动累积~(222)Rn-~(222)Rn探测器

本文采用 2只扩散杯 ,一只选择渗透率较大的滤膜 ,使2 2 2 Rn和2 2 0 Rn能很容易的进入。另一只选择渗透率较小的滤膜 ,该滤膜只允许2 2 2 Rn进入 ,半衰期较短的2 2 0 Rn被阻挡在外面。通过不同滤膜扩散率的差异 ,改变探测器的空气交换率 ,从而达到同时测量2 2 2 Rn和2 2 0 Rn的目的     

^14C标记农药杀螟松和马拉硫磷的制备

以Ｂａ＾１４ＣＯ３为起始原料制得＾１４ＣＨ３ＯＨ，然后和＾１４ＣＨ３ＯＨ与ＰＳＣｌ３在碱性条件下反应，再加入甲基砂基苯酚，在甲基异丁酮溶剂体系下制得＾１４Ｃ－刹螟松，放化纯度〉９５％，放射性比活度为１８８．７ＢＭｑ／ｍｏｌ，＾１４ＣＨ２ＯＨ与Ｐ２Ｓ５合成的中间体，加顺丁烯酸二乙酯在甲苯溶剂体系中反应制成＾１４Ｃ－马拉硫磷，放化纯度〉９５％，放射性比活度为１５６．４ＭＢｑ／ｍｏｌ。     

Model-based cross section calculations on production of ~(43,34)Sc,~(45)Ti,~(51)Cr,~(54)Mn,and ~(55)Fe radioisotopes

A cross section database on excitation functions of reactions produced by charged particles is essential for many areas of nuclear research. Particularly, accurate knowledge on nuclear cross sections for the cyclotron production of radioisotopes is very important for nuclear medicine. In the present paper, the cross section calculations for the production of~(43),~(34)Sc,~(45)Ti,~(51)Cr,~(54)Mn, and~(55) Fe radioisotopes were carried out by the use of ALICE/ASH code using the Fermi gas model, Kataria Ramamurthy Fermi gas model, and superfluid nuclear model for nuclear level density. Thereby, these model calculations were compared with the available measured data.     

~(107)Ag(d,2n)~(107)Cd和~(109)Ag(d,2n)~(109)Cd反应的激发函数

用13.4MeV的氘束轰击天然银迭靶,银箔前后用铝箔作捕集减能膜。实验确定了~(107)Ag(d,2n)~(107)Cd和~(109)Ag(d,2n)~(109)Cd反应的激发函数,同时作了理论计算。由结果可见,实验值与理论值吻合得很好。     

Measurement of ~(59)Ni and ~(63)Ni by AMS

正The long lived isotopes ~(59)Ni and ~(63)Ni can be used in many areas such as radioactive waste management,neutron dosimetry,cosmic radiation study,and so on.Based on the large accelerator and a big Q3D magnetic spectrometer,the measurement method for ~(59)Ni and ~(63)Ni is under development at the AMS facility at China Institute     

^179Hf（n,2n）^178Hf^m2和^209Bi（n,2n）^208Bi反应截面的测量

用活化法测量相对于~(93)Nb(n,2n)~(92)Nb~m反应的~(179)Hf(n,2n)~(178)Hf~(m2)的反应截面和相对于~(27)Al(n,2n)~(24)Na反应的~(209)Bi(n,2n)~(208)Bi的反应截面。在中子能量为14.4 MeV处~(179)Hf(n,2n)~(178)Hf~(m2)反应的测量截面为(6.04±0.32)×10~(-31)m~2。在中子能量为14.6 MeV处~(209)Bi(n,2n)~(208)Bi反应的测量截面为(2279±173)×10~(31)m~2。在这些测量中,中子能量是用~(90)Zr(n,2n)~(89)Zr~(m+8)反应和~(93)Nb(n,2n)~(92)Nb~m反应的截面比法测定的。