共查询到20条相似文献,搜索用时 187 毫秒
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皮肤隐球菌病为少见的深部真菌感染性疾病,原发于口腔颌面部的感染尤为少见。临床上极易误诊,笔者遇到1例面部原发性皮肤隐球菌病,经细菌学培养及皮肤组织病理检查确诊,经手术治愈,追踪观察18个月未见复发,现报道如下。 相似文献
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儿童全身播散性隐球菌病1例 总被引:1,自引:1,他引:0
儿童全身播散性隐球菌病1例刘德明,曾庆玉,王华隐球菌病是由新生隐球菌引起,全身播散性损害罕见,最近我们收治1例有皮肤、淋巴结、肺、骨及中枢神经系统损害的隐球菌病患儿,现报告如下。患儿胡×,女,6岁。因发热、咳嗽、胸痛6个月,伴有皮疹3个月入院。起病初... 相似文献
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廖万清 《国际皮肤性病学杂志》1983,(1)
隐球菌病大部分原发于肺部,常常播及脑膜和脑实质.播散性隐球菌病偶可累及皮肤.原发性皮肤隐球菌病是指皮肤损害是其唯一的表现,而无系统性或脑脊液的侵犯.本病较为罕见,可以在含有新型隐球菌的异物损伤皮下以后而出现.作者报告一例男性患者,81岁,因左前臂红肿痛一个月而就诊.查局部红肿湿润,渗出少量脓液,近卫淋巴结不大.给予红霉素治疗无效,且损害继续扩大,以至形成10×6.5cm溃疡.检查肺、神经系统及其他系统无异常.溃疡区活检表现为慢性炎症,可见多数淋巴细胞、组织细胞和少数多形核白细胞浸润.有多数胶样厚荚膜孢子,偶见巨细胞.溃疡组织在沙氏葡萄糖琼脂培养为新型隐球菌生长.此时作痰、尿、脑脊液直接镜检和培养均为阴性.遂 相似文献
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《中国医学文摘:皮肤科学》2017,(5)
隐球菌病(cryptococcosis)是一种重要的世界性人兽共患的感染性真菌病,可侵犯人体的肺、脑、皮肤、骨骼等全身各脏器。因其强烈的嗜中枢性,所致的隐球菌性脑膜炎/脑膜脑炎(cryptococca meningitis/meningoencephalitis,CME)约占隐球菌感染的80%以上,具高病死率。现从流行病学、临床表现、实验室诊断及治疗几方面阐述隐球菌病诊治方面的进展。 相似文献
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赖松青 《国际皮肤性病学杂志》1991,(2)
kaposi肉瘤及播散性隐球菌病在一般人群中均罕见,但在免疫受损的患者中发病率明显增加.本文报告1例艾滋病(AIDS)患者,患有口腔Kaposi肉瘤及播散性皮肤隐球菌病.患者41岁, 相似文献
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A 42-year-old white male without prior skin disease presented 8 months ago with chest pain, fever, and coughing to his primary physician. At that point, he had no skin lesions. The diagnosis was made by standard blood tests. The patient completed treatment and was symptom free for 8 months until he presented to his physician again with skin lesions on his right cheek and extremities. The patient was referred to our dermatology clinic for further evaluation. A complete skin examination revealed lesions on his face, extremities, and back. The lesions on his right face were 8 x 10-mm erythematous papules and nodules coalescing into a plaque. A biopsy was taken from his right cheek lesions. 相似文献
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Matsushima S Horiguchi Y Honda T Fujii S Okano T Tanabe M Wakayama T Hashimoto T Yancey KB 《The Journal of dermatology》2004,31(1):10-15
A 68-year-old Japanese male with a five-year-history of lung carcinoma showed recurrent blisters and erosions on the oral and genital mucosae and the skin. The patient complained of dyspnea due to severe laryngeal stenosis and underwent a tracheostomy. A skin biopsy specimen showed a subepidermal blister and linear deposits of IgG and C3 at the basement membrane zone of the epidermis. Indirect immunofluorescence examination demonstrated circulating IgG anti-basement membrane zone autoantibodies that reacted to epiligrin on immunoblotting. Based on a diagnosis of anti-epiligrin cicatricial pemphigoid, he was treated with prednisolone, minocycline hydrochloride and nicotinamide. Although no new skin lesions appeared, he died of lung carcinoma five months after the tracheostomy. A review of reported cases with anti-epiligrin cicatricial pemphigoid in Japan disclosed that 5 of 16 cases (31.2%) were complicated by internal malignancies. 相似文献
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Emi Yamazaki Katsuko Kikuchi Yoji Sasahara Michihiro Kono Masashi Akiyama Setsuya Aiba 《The Journal of dermatology》2020,47(1):58-60
A case of atopic dermatitis (AD) with X-linked agammaglobulinemia (XLA), which is one of the primary immunodeficiency diseases, is reported. A 12-year-old boy had suffered from dry skin and recurrent itchy eruptions since he was 2 years old, and he was diagnosed as having XLA at the age of 4 years. His total immunoglobulin (Ig)E level was 7 IU/mL, even with regular Ig replacement therapy. Furthermore, filaggrin (FLG) mutations known in the Japanese population were not found. His skin lesions were well controlled by the application of a mild-class topical steroid and a moisturizer, though he developed folliculitis due to Staphylococcus aureus infection during treatment with a strong-class topical steroid. This case suggests that the FLG mutation and IgE-mediated sensitization are not necessary to induce AD skin manifestation. 相似文献
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A 7-year-old boy was examined for cutaneous lesions that were localized to the side of the body on which he slept and occurred on skin in direct contact with an enuresis blanket. The painless skin lesions were similar to the punched-out skin ulcers and atrophic scars reported in the British literature as buzzer ulcers. Exposure of the child's skin to electrical current may have produced the lesions, which ceased to appear when use of the enuresis blanket was discontinued. 相似文献
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The development of acute graft‐versus‐host‐disease (GVHD) in recipients of donor lymphocyte infusion (DLI) is not rare and the complication is quite often fatal. We describe a severe skin GVHD patient who responded well to basiliximab. A 20‐year‐old male who received a hematopoietic stem cell transplantation at his age of 18. His fusion gene Aml1/Eto remained positive, so he was administered with DLI combined with interferon‐a (IFN‐a). Forty days after the therapy, he presented with severe skin rashes with multiple mucous membrane involvement. The skin and mucous lesions recovered after basiliximab treatment. So far, severe type of erythema multiforme in GVHD patients after DLI with IFN‐a injection is firstly reported here, together with a new alternative therapy. 相似文献
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A case of piroxicam photosensitivity in a 42-year-old man is reported. While he was taking piroxicam, eczematous skin lesions on sun-exposed skin and vesicular hand dermatitis on the finger webs and palms developed. He showed a lowered minimal erythema dose (MED) to UVA when a rechallenge with piroxicam was attempted. Photopatch testing with piroxicam was positive. 相似文献
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Multiple plasma cell tumours of the skin may, on rare occasions, precede clinical, radiological and laboratory evidence of systemic myelomatosis. A man presented with several plasma cell tumours of the skin but with no detectable evidence of the disseminated myelomatosis to which he succumbed 16 months later. Multiple cutaneous extra-medullary plasmacytomas should be regarded as a cutaneous expression of multiple myelomatosis. 相似文献
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Elser I Hassan AS Rieker J Ruzicka T Megahed M 《Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete》2003,54(4):368-370
A 30-year old male patient presented with a rare congenital pigment disturbance, dyschromatosis universalis hereditaria. Clinically, he displayed mottled hyperpigmentation covering almost the entire skin surface with accentuation in skin folds. The lesions had been present since birth. He was the only family member showing these changes. He had no other medical problems and took no medications. 相似文献