多巴胺对骨修复材料表面改性的研究进展

随着骨缺损病患的日益增多,对骨修复材料的要求越来越高,寻求有效的方法使骨修复材料实现功能化,以改善材料与骨组织之间的相互作用及促进骨组织快速修复成了关键所在。海洋生物贻贝分泌的粘附蛋白在水环境中展现出超强粘附性能,能牢固附着于各种材料表面。受粘附蛋白启发,研究发现多巴胺(Dopamine,DA)具有与贻贝粘附蛋白类似的结构和性能,其具有超强粘附性、化学反应活性以及生物相容性;特别是其对骨细胞有优异的粘附、增殖效果,有望用于骨修复材料的表面改性。着重介绍了DA的主要性能以及其在骨修复材料表面改性方面的研究进展。     

分子自组装技术基底材料的研究进展

综述了用于分子自组装技术的基底材料的种类及自组装分子膜的制备过程,结合多种表征方法的测试结果介绍了各类自组装分子膜的吸附特性、组装机理、功能特点、应用领域及影响薄膜性能的各种因素,还介绍了在自组装单分子膜表面制备其它无机功能薄膜的研究结果。     

金属基骨植入材料表面生物活性的研究进展

介绍了几种金属骨植入材料，根据生物活性定义、生物材料与组织间的结合方式，探讨了金属表面生物活性机制和影响表面生物活性的因素，分析了在金属基骨植入材料表面可制备的生物活性涂层，并对金属基骨植入材料表面活性的研究前景进行了展望。     

生物医用高分子材料表面改性研究进展

生物医用高分子是高分子科学的一大发展,在众多的高分子材料中,最杰出的代表典范——生物医用有机硅化合物,自60年代起就一直广泛应用在临床医学以下几个方面,并显示了广阔的应用前景:人工脏器、植入装置、修复外科、软骨组织、氧透气膜、神经组织、心脏瓣膜、金属涂层等脏器与修复材料。     

有机-无机杂化材料研究进展

综述了有机－无机杂化材料的制备方法及影响材料结构和性能的因素,并对有机－无机碳化材料在力学,光学,电学等领域的应用进行了简要的评述。这类性能优异的新材料在未来的高科技领域必须有广阔的应用前景。     

骨植入医用钛合金表面改性涂层研究进展

钛合金具有优良的力学性能以及良好的生物相容性,使其广泛应用于骨植入生物医药领域.随着植入物性能要求的不断提高,力学性能优异的高强模比新型医用钛合金逐渐被开发,同时,由于钛合金存在表面细胞粘附性差等骨整合问题,通过表面改性来提升钛合金生物相容性成为医用钛合金的研究焦点.概述了骨植入医用钛合金的发展历程和常用的表面改性涂层...     

等离子体表面技术和在有机材料改性应用中的新进展

综述了20世纪90年代以来低温等离子体表面技术及其在有机材料改性应用中的新进展。介绍阻挡放电和远等离子体处理是实现工业化和获得更好的等离子体表面改性的新方法。目前的研究更多地关注于等离子体接枝表面改性,即将不同性能的单体接枝于用等离子体处理过的材料表面获得永久性表面改性,以提高材料的粘附性、吸湿性、吸附性、导电性和生物相容性等。对低温等离子体表面改性技术的研究和应用进行了展望。     

纳米SiO2改性可生物降解材料研究进展

纳米SiO2无毒,无味,无污染,具有优异的纳米特性,与高分子聚合物具有良好的相容性,被广泛应用于改善可生物降解材料性能等领域。综述了纳米SiO2的分散稳定性能,以及纳米SiO2改性聚乳酸、聚乙烯醇等合成型生物降解材料与淀粉、纤维素、壳聚糖、蛋白质、木质素等天然高分子材料的研究进展,并从降低价格及增强性能方面,对其改性可生物降解材料替代某些通用塑料的应用前景进行了展望。     

正极材料掺杂与表面改性的研究进展

掺杂和表面改性是稳定锂离子二次电池正极材料结构、改善其电性能的有效方法.综述了国内外近年来正极材料掺杂与表面改性的研究进展,介绍了镍系和锰系正极材料掺杂与表面改性对其结构和电性能的影响,并从促进Li 、电子传递和稳定结构2个方面进行了归纳,认为今后研究掺杂的重点应放在掺杂元素的选择、掺杂离子在晶体中的分布、掺杂离子价态的变化、掺杂离子相互间协同作用机理等方面.而表面改性将向着研究更为稳定的、Li 透过率更高的薄膜方向发展.     

MOFs材料改性及其吸附二氧化碳的研究进展

化石燃料燃烧后产生的二氧化碳气体的大量排放引起了人们的极大关注.CO2吸附捕获具有技术可靠、成本低等特点,应用前景广阔.金属有机骨架材料(MOFs)具有良好的化学稳定性和热稳定性,以及独特微孔结构而成为一种高效的CO2吸附材料.重点介绍了使用MOFs进行CO2吸附捕集的最新研究进展,总结了MOFs材料的制备、改性方法及...     

Surface modification of hexagonal boron nitride nanomaterials: a review

Hexagonal boron nitride (h-BN) nanomaterials, such as boron nitride nanotubes, boron nitride nanofibers, and boron nitride nanosheets, are among the most promising inorganic nanomaterials in recent years. Their unique properties, including high mechanical stiffness, wide band gap, excellent thermal conductivity, and thermal stability, suggest many potential applications in various engineering fields. In particular, h-BN nanomaterials have been widely used as functional fillers to fabricate high-performance polymer nanocomposites. Like other nanomaterials, prior to their utilization in nanocomposites, surface modification of h-BNs is often necessary in order to prevent their strong tendency to aggregate, and to improve their dispersion and interfacial properties in polymer nanocomposites. However, the high chemical inertness and resistance to oxidation of h-BNs make it rather difficult to functionalize h-BNs. The methods frequently used to oxidize graphitic carbon nanomaterials are not quite successful on h-BNs. Therefore, many novel approaches have been studied to modify h-BN nanostructures. In this review, different surface modification strategies were discussed including various covalent and non-covalent surface modification strategies through wet or dry chemical routes. Meanwhile, the effects of these surface modification methods on the resulting material structures and properties were also reviewed. At last, a number of theoretical studies on the reactivity of h-BNs with different chemical agents have been conducted to explore new surface modification routes, which were also addressed in this review.     

Surface modification of cathode materials for lithium ion batteries

We have studied the effect of surface modification with aluminum hydroxide and alumina-boehmite mixtures on the electrochemical performance of an equimolar LiCoO₂/LiMn₂O₄ composite cathode material. A process has been developed for the deposition of aluminum hydroxide nanocoatings using ultrasonic processing. Al(OH)₃ nanocoatings, as well as alumina-boehmite nanocoatings, considerably improve the cyclability of the composite in an extended voltage range (up to 4.5 V) in comparison with the unmodified material, with an insignificant reduction in specific capacity in the first cycles. Both types of coatings markedly improve the cyclability of the composite at high current rates in comparison with the unmodified composite.     

A review of asbestos substitute materials in industrial applications

Asbestos is a fibrous material which makes a great contribution to human safety through its use in (among other things), fire protection materials and car brake linings. But it can also constitute a major health hazard to those who are exposed to the fine airborne fibres.This paper examines the properties and applications of asbestos, including those which lead to its being a health hazard. Over 1000 applications exist and only the more important of these are considered.Some comments are made relating to the possible health hazards arising from some substitute materials.     

Surface modification of implant materials and its effect on attachment and proliferation of bone cells

Osteoblast-like cell response in variation with the air plasma sprayed (APS) TiO2 coating process parameters correlated with coating properties were investigated to evaluate the durability and biocompatibility of the surface-modified implant. The Taguchi technique was used to determine the coating properties affected by plasma spraying parameters on Ti-6AI-4V alloy substrate. The coating properties were characterized by porosity and surface roughness using an image analyzer and surf analyzer, respectively. The MG-63 osteoblast like cell morphology and proliferation data on TiO2 coated substrate were measured by SEM observation and direct cell counting. It was demonstrated that surface roughness increased as spray distance decreased but gas flow rates and spray distance were major factors in the case of porosity. The osteoblast adhesion morphology and proliferation data indicated that osteoblast-like cell morphology was not influenced by process parameters, but cell proliferation was affected to some extent by surface roughness and porosity among TiO2 coated specimens. Specifically, the difference between those of substrate and coating layer was relatively more visible.     

Interfacial and biological properties of the gradient coating on polyamide substrate for bone substitute

Fabrication of bioactive and mechanical matched bone substitutes is crucial for clinical application in bone defects repair. In this study, nano-hydroxyapatite/polyamide (nHA/PA) composite was coated on injection-moulded PA by a chemical corrosion and phase-inversion technique. The shear strength, gradient composition and pore structure of the bioactive coating were characterized. Osteoblast-like MG63 cells were cultured on pure PA and composite-coated PA samples. The cells'' adhesion, spread and proliferation were determined using MTT assay and microscopy. The results confirm that the samples with the nHA/PA composite coating have better cytocompatibility and have no negative effects on cells. To investigate the in vivo biocompatibility, both pure PA and composite-coated PA cylinders were implanted in the trochlea of rabbit femurs and studied histologically, and the bonding ability with bone were determined using push-out tests. The results show that composite-coated implants exhibit better biocompatibility and the shear strength of the composite-coated implants with host bone at 12 weeks can reach 3.49 ± 0.42 MPa, which is significantly higher than that of pure PA implants. These results indicate that composite-coated PA implants have excellent biocompatibility and bonding abilities with host bone and they have the potential to be applied in repair of bone defects.     

Macroporous hybrid frameworks for bone graft substitute

Hybrid nanocomposite of poly(methyl methacrylate) reinforced with hydroxyapatite has been fabricated by phase separation mechanism of the polymer in the presence of a solvent having low solubility. The process demonstrates the formation of a three-dimensional honeycomb like macroporous structure of the hybrid material having struts patterned with micropores. Such mechanically stable open cell foam like structure has a potential to be used as a non-resorbable bone implant.     

Surface modification of polylactic acid by ion,electron beams and low-temperature plasma: a review

Journal of Materials Science - We review the work that has been done on the modification of polylactic acid by irradiation methods including low-temperature plasma treatment, electron-beam...