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IntroductionNeonates appear to be less affected by COVID-19 than adults, yet COVID-19 has been a challenge for all medical specialties, including neonatal intensive care unit (NICU) specialists. Unfortunately, current knowledge about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is limited. This case report explains how COVID-19 neonatal sepsis was treated with immunomodulatory agents.Case presentationIn this case, we present a premature male newborn who was ill. He was born to a mother with a negative nasopharyngeal swab test for SARS-CoV-2. On the fifth day of life, the baby developed respiratory distress, and a nasopharyngeal swab test for SARS-CoV-2 tested positive. The baby was Intubated, and intratracheal surfactant was administered. The infant was treated with intravenous immunoglobulin (IVIg) and corticosteroids for 14 days.Patient's demographicsAge: under 1 month, Sex: Male, Ethnicity: Iranian.ConclusionThe basics of treatment for neonatal COVID-19 is supportive care. Some studies have treated infants with various drugs such as Hydroxychloroquine, Favipiravir, and Remedsivir; however, in our case, a 5-day-old baby boy was treated with corticosteroids and IVIg. We achieved good outcomes after 2 weeks of treatment with dexamethasone 0.3 mg/kg per day and IVIg 2 g/kg/day (for 3 days). It appears that these treatments, along with adjuvant ventilation and the administration of endotracheal surfactant, can improve a patient's general condition.  相似文献   

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Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2,has posed a serious threat to global public health security.With the increase in the number of confirmed cases globally,the World Health Organization has declared the outbreak of COVID-19 an international public health emergency.Despite atypical pneumonia as the primary symptom,liver dysfunction has also been observed in many clinical cases and is associated with the mortality risk in patients with COVID-19,like severe acute respiratory syndrome and Middle East respiratory syndrome.Here we will provide a schematic overview of the clinical characteristics and the possible mechanisms of liver injury caused by severe acute respiratory syndrome coronavirus 2 infection,which may provide help for optimizing the management of liver injury and reducing mortality in COVID-19 patients.  相似文献   

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自新型冠状病毒(SARS-CoV-2)感染的肺炎疫情发生以来,确诊人数不断增加,及时有效的预防、治疗成为目前对于该病的关键。通过文献阅读及临床数据综合来看,采用中西医结合治疗作用突出,效果显著,中医药已成为不可或缺的一部分。笔者就目前对于该病认识、病因病机、诊断治疗、临床疗效、预后康复做一综述。  相似文献   

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<正>新型冠状病毒(简称“新冠”)感染以发热、干咳、乏力为主要表现,部分患者出现咽痛、鼻塞及流涕等上呼吸道感染症状,儿童症状相对成人较轻[1]。研究[2-3]显示,儿童肥胖、合并有基础性疾病是儿童感染危重型新冠的高危因素,其中合并神经系统及呼吸系统疾病是最为常见的影响因素。重型及危重型患儿通常需要行呼吸支持,在此过程中气道廓清技术(airway clearance therapy,ACT)有着举足轻重的作用。  相似文献   

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快速建议指南是为应对突发公共卫生事件,在短时间内用科学、规范的方法制订的指南。其主要特点是能在保证指南科学性的基础上,尽可能缩短指南制订周期,因此常用于指导和应对突发公共卫生事件或紧急情况。本文将介绍快速建议指南的定义、特点、现状、适用情况、制订流程和优势与局限性,以期为相关指南制订者和研究者提供参考,为快速建议指南更好地在我国发展提出思考与建议。  相似文献   

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2019年12月以来,新型冠状病毒引发的疾病已成为全国的突发公共卫生事件,对人民群众健康和生命构成严重威胁.中国医师协会超声医师分会、中华医学会超声医学分会等行业学会分别发布了有关新冠疫情下超声人员防护、超声仪器管理等多个建议案.但在实际工作中,由于受诊区固有设计、诊室固有布局、防护用品短缺等多种因...  相似文献   

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In barely nine months, the pandemic known as COVID-19 has spread over 200 countries, affecting more than 22 million people and causing over than 786 000 deaths. Elderly people and patients with previous comorbidities such as hypertension and diabetes are at an increased risk to suffer a poor prognosis after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although the same could be expected from patients with chronic obstructive pulmonary disease (COPD), current epidemiological data are conflicting. This could lead to a reduction of precautionary measures in these patients, in the context of a particularly complex global health crisis. Most COPD patients have a long history of smoking or exposure to other harmful particles or gases, capable of impairing pulmonary defences even years after the absence of exposure. Moreover, COPD is characterized by an ongoing immune dysfunction, which affects both pulmonary and systemic cellular and molecular inflammatory mediators. Consequently, increased susceptibility to viral respiratory infections have been reported in COPD, often worsened by bacterial co-infections and leading to serious clinical outcomes. The present paper is an up-to-date review that discusses the available research regarding the implications of coronavirus infection in COPD. Although validation in large studies is still needed, COPD likely increases SARS-CoV-2 susceptibility and increases COVID-19 severity. Hence, specific mechanisms to monitor and assess COPD patients should be addressed in the current pandemic.  相似文献   

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目的 疫情形式仍然严峻,积极响应国家“战役”号召,以网络化平台为助力,以提升护士岗位胜任力为核心,探索在线护士培训模式,并总结培训实践体会,为当下医疗机构有效组织培训提供借鉴与参考。方法 对全院护士开展针对性培训,从护理基础理论知识、常用临床技能操作、新冠肺炎新冠常识知识及规范防护技能、临床应对能力以及自我心理建设等各方面统筹护士岗位胜任力的提升。结果 全院护士理论知识考核及实践技能通过率达100%;赴武汉一线支援护士以及轮岗我院发热门诊护士实现“零感染”;有效舒缓护士心理压力;护士对培训满意度达95%以上;录制的护理技术操作得到有效推广。 结论 大疫下以提升岗位胜任力为核心的在线护士培训模式,有效提升护士岗位胜任力,培训内容恰适,形式便捷,便于借鉴推广。  相似文献   

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<正>2019年12月出现的新型冠状病毒(新冠)肺炎疫情极大程度地改变了全球的经济、生活和医疗。新冠病毒感染后除了对呼吸系统有急性影响外,还对其余系统及患者的心理等有持续性的影响。有研究者对核酸转阴后3个月以上的120名患者进行了血生化方面的评测,评测发现受检患者存在多项临床和血生化指标的改变:收缩压、红细胞沉降率、C反应蛋白、D-二聚体、丙氨酸氨基转移酶、天冬氨酸氨基转移酶等指标呈升高,血清白蛋白则明显降低(P≤0.001)[1]。  相似文献   

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目的:探讨普通型新型冠状病毒肺炎(COVID-19)患者住院期间咽拭子新型冠状病毒(SARS-CoV-2)核酸检测转阴后复阳的发生率及可能因素。方法:多次采集2020年2月2日至2020年3月10日武汉大学人民医院东院收治的40例确诊的普通型COVID-19患者咽拭子,采用实时反转录聚合酶链反应(RT-PCR)法进行SARS-CoV-2核酸检测。结果:所有患者在首次RT-PCR检测结果呈阴性后,第2次RT-PCR检测结果为阳性12例(30%),连续2次RT-PCR检测为阴性第3次检测为阳性的患者为13例(32.5%),连续3次RT-PCR检测阴性第4次检测为阳性的患者为3例(7.5%),连续4次RT-PCR检测为阴性第5次检测为阳性的患者为0例。结论:作为COVID-19患者确诊及出院的重要指标,咽拭子核酸检测存在一定的假阴性率。  相似文献   

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目的 探讨对进入新型冠状病毒肺炎隔离病区的医护人员进行规范化岗前培训的效果。方法 新型冠状病毒肺炎疫情通报以来,无锡市第五人民医院迅速反应,综合分析以往应对突发公共卫生事件的经验,根据新型冠状病毒流行病学特点,修订了隔离病区规范化岗前培训手册,并对预进入隔离病区的180名医护人员进行基本知识、技能培训考核及心理干预,比较岗前培训前后医护人员基本知识掌握率、消毒隔离防护用品穿脱技能合格率以及焦虑、抑郁量表(SDS、SAS)评分。结果 通过积极落实隔离病区规范化岗前培训,医护人员基本知识掌握率(97.22%)高于培训前(67.78%);消毒隔离及防护服穿脱技能合格率(98.89%)高于培训前(60.56%);SDS评分从(0.59±0.26)分降低至(0.50±0.15)分,SAS评分从(59.44±7.12)分降低至(50.36±5.17)分,差异有统计学意义(均P<0.05)。结论 为应对新型冠状病毒肺炎疫情,对进入隔离区病房的医护人员进行规范化岗前培训可以提高其基本知识和操作技能的掌握程度,通过心理干预可以降低医护人员的焦虑、抑郁心理状态,确保医护人员提供更高效的医疗护理。  相似文献   

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In December 2019, an outbreak of unexplained pneumonia was reported in Wuhan, China. The World Health Organization officially named this disease as novel coronavirus disease 2019 (COVID-19). Liver injury was observed in patients with COVID-19, and its severity varied depending on disease severity, geographical area, and patient age. Systemic inflammatory response, immune damage, ischemia-reperfusion injury, viral direct damage, drug induce, mechanical ventilation, and underlying diseases may contribute to liver injury. Although, in most cases, mild liver dysfunction is observed, which is usually temporary and does not require special treatment, the importance of monitoring liver injury should be emphasized for doctors. The risk of COVID-19 infection of liver transplantation recipients caused more and more concerns. In this article, we aimed to review the available literature on liver injury in COVID-19 to highlight the importance of monitoring and treating liver injury in COVID-19.  相似文献   

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