N-[(4-溴-3,5-二氟)苯基]马来酰亚胺合成

以马来酸酐和4-溴-3,5-二氟苯胺为原料,对甲苯磺酸为催化剂,甲苯/DMF为混合溶剂,采用溶剂共沸法,制备了N-[(4-溴-3,5-二氟)苯基]马来酰亚胺,用FTIR、1HNMR和13CNMR对产物进行了结构表征,并对合成工艺进行优化,所得适宜工艺条件(以4-溴-3,5-二氟苯胺38.6 mmol计):催化剂对甲苯磺酸用量0.877 8 g,n(马来酸酐)/n(4-溴-3,5-二氟苯胺)=1.2,胺化反应时间为1.5 h,环化反应时间为2 h,产率可达92.6%。     

N-苯基马来酰亚胺的合成

以苯胺和顺丁烯二酸酐为原料，采用两步法合成N-苯基马来酰亚胺，确定了最佳反应条件。分析各因素对产品收率的影响，并对产品相关物理性质进行了测定。N-苯基马来酰亚胺收率92％以上。     

N-[4-(α-溴代丁酰氧基)苯基]马来酰亚胺的合成与表征

通过分子设计合成了一种能进行自引发聚合的新型取代苯基马来酰亚胺单体N-[4-(α-溴代丁酰氧基)苯基]马来酰亚胺(AB^*)。研究了催化剂用量、反应温度和时间等因素对合成反应的影响,得出了优化反应条件。采用NMR、FT-IR等对目标及中间产物的结构进行了表征。     

合成N-苯基马来酰亚胺的研究

以马来酸酐和苯胺为原料合成N-苯基马来酰亚胺(N-PMI)的过程中，采用对甲苯磺酸和硫酸铜为催化剂，对羟基苯甲醚为阻聚剂，并采用甲苯／二甲基甲酰胺混合溶剂，有效提高了N-苯基马来酰亚胺的产率。加入金属铜盐催化剂后，N-苯基马来酰亚胺的纯度提高到99．4％左右。同时研究了反应物摩尔比、催化剂用量以及混合溶剂配比等因素对合成N-苯基马来酰亚胺的影响。     

N-苯基马来酰亚胺的合成与表征

以顺丁烯二酸酐和苯胺为原料,研究在催化剂作用下合成N_苯基马来酰亚胺（N—PMI）的新工艺,在N-苯基马来酰胺酸合成时采用乙酸已酯作溶剂,在N-PMI合成时采用乙二胺四乙酸（EDTA）钠盐作为催化剂、醋酐作为脱水剂、丙酮作为溶剂,考察了原料配比、催化剂的选择及用量、反应温度与反应时间等因素对反应结果的影响,合成N-PMI的最佳工艺条件为：顺酐与苯胺质量比为1．06：1,0,催化剂用量为O．35g／g中间体,反应温度为55℃,反应时间为4h。在最佳工艺下产品收率可达92％以上,产品纯度可达99％（质量分数）以上,并通过气相色谱检测了产品纯度,通过红外光谱对产品结构进行了表征。     

N-苯基马来酰亚胺的合成工艺研究进展

介绍了国内外N-苯基马来酰亚胺的主要合成方法及最新研究进展,对现有合成工艺的优缺点进行了比较分析,并结合生产实际,指出了N-苯基马来酰亚胺合成的未来发展趋势.     

N-苯基马来酰亚胺的应用与合成

叙述了N -苯基马来酰亚胺的用途及合成方法。通过分析ABS及PVC的市场前景 ,提出了在国内开发N -苯基马来酰亚胺的必要性和紧迫性。     

N-苯基马来酰亚胺的合成及应用进展

叙述了国内外N-苯基马来酰亚胺的几种制备方法,论述了其作为新一代树脂耐热改性剂在ABS及PVC树脂改性以及其它方面的应用。     

N-(4-羟基苯基)马来酰亚胺改性酚醛树脂的制备与表征

采用N-(4-羟基苯基)马来酰亚胺(4-HPM)改性酚醛树脂(PF),改性后PF的耐热性能明显优于传统的热塑性PF。质量分数2%的4-HPM改性PF的热分解温度比纯PF提高104.6℃,冲击强度提高130%。改性PF的固化过程分为两个固化阶段:第一阶段是少量羟甲基的缩合;第二阶段为马来酰亚胺的双键打开进行自交联。     

N-苯基马来酰亚胺的生产和应用前景

综述了N-苯基马来酰亚胺的用途及合成方法，指出了我国N-苯基马来酰亚胺的开发前景。     

Radical polymerization of N-[(1-n-butoxycarbonyl)ethyl]maleimide

Poly(N-[(1-n-butoxycarbonyl)ethyl]maleimide) (PBAM) was synthesized by solution polymerization with 2,2′-Azobis(isobutylronitrile) (AIBN) as radical initiator. The resulting polymer(PBAM) was characterized by infrared spectroscopy (IR), themogravimetry (TG), and differential thermal analysis (DTA). The initial decomposition temperature of PBAM is 321.6°C; the glass transition temperature of PBAM was 240.5°C. The effects of solvent, temperature, initiator concentration ([I]), and monomer concentration ([BAM]) on polymerization were also discussed. The overall activation energy (E_a) of homopolymerization was determined (E_a = 93.5 kJ/mol). It was revealed that the rate of polymerization (R_p) can be expressed as R_p ∝ [I]^0.58[BAM]. © 2001 John Wiley & Sons, Inc. J Appl Polym Sci 82: 424–427, 2001     

N-(4-羟基苯基)马来酰亚胺的合成研究

合成了N-(4-羟基苯基)马来酰亚胺，采用FT-IR对其进行结构表征，考察了合成过程中的多种影响因素，获得了最佳条件的工艺参数。     

2-(2-咪唑基)-(4-正丁氧基)苯甲酰苯胺的合成工艺改进

2-(2-咪唑基)-(4-正丁氧基)苯甲酰苯胺具有潜在的抗肿瘤效应。本文通过改进合成路径,经过关环反应、还原反应以及酰化反应,成功合成了化合物2-(2-咪唑基)-(4-正丁氧基)苯甲酰苯胺(6),六步反应总收率达到30%,且各步反应都能放量反应,反应中间体及目标化合物结构经MS、1H NMR、13C NMR确证。     

N—（4—羟基苯基）马来酰亚胺的合成研究

以顺丁烯二酸酐(MA)、对氨基苯酚(4-AP)为原料,一步法合成了N-(4-羟基苯基)马来酰亚胺(4-HPM)。本文研究了原料配比、反应时间和催化剂用量等因素对产率的影响,并对产物物理性能进行了研究。     

N-对羧基苯基马来酰亚胺的制备与表征

以顺丁烯二酸酐(MAn)和对氨基苯甲酸(P-AA)为原料、乙酸乙酯为溶剂、无水醋酸钠为脱水催化剂合成了N-对羧基苯基马来酰亚胺(P-CPMI)，并采用元素分析、核磁共振、红外光谱对目标产物的结构进行了表征。     

N-[(3,4,5-三氟)苯基]丙烯酰胺的合成及溶解度测定

以3,4,5-三氟苯胺和丙烯酰氯为原料,碳酸氢钠为缚酸剂,制得N-[(3,4,5-三氟)苯基]丙烯酰胺(TFPA).用红外光谱、核磁共振氢谱和核磁共振碳谱对TFPA进行结构表征.探讨原料物质的量比、碳酸氢钠用量、反应温度、反应时间对TFPA收率的影响.获得适宜反应条件为:3,4,5-三氟苯胺和丙烯酰氯物质的量比为1:1...     

Free Radical Copolymerization of Methyl Methacrylate and Styrene with N-(4-Carboxyphenyl)maleimide

The free radical copolymerization of methyl methacrylate (MMA) or styrene (St) with N-(4-carboxyphenyl)maleimide (CPMI) was carried with AIBN as an initiator in THF solvent at 80°C. A series of copolymers of MMA and St with CPMI were prepared using different feed ratios of comonomers. The values of monomer reactivity ratios (r₁, r₂) determined by Fineman-Ross and Kelen-Tudos methods are 0.26 and 2.51 in the CPMI/MMA system and 0.08 and 0.22 in the CPMI/St system. Alfrey–Price Q-e values for CPMI were calculated as Q = 1.05 and e = 0.41 in the CPMI/MMA system and Q = 1.21 and e = 0.91 in the CPMI/St system. The polymer samples have been characterized by solubility tests, intrinsic viscosity measurements, FT-IR and ¹H-NMR spectral analysis, and thermo-gravimetric analysis. It was found that the initial and final decomposition temperatures increased with increasing the amount of CPMI in the copolymer. The integral procedural decomposition temperature and energy of activation of thermal degradation have also been reported.     

N-[(S)-1-(乙氧羰基)-3-苯丙基]-L-丙氨酸的合成

以苯乙酮和乙醛酸为原料制得3-苯甲酰基丙烯酸乙酯,与L-丙氨酸苄酯对甲苯磺酸盐经迈克尔加成、还原、拆分制得标题化合物,总收率约20%,纯度达99.8%。该方法简单可行,工艺可靠。     

Synthesis and properties of silicon-containing maleimide polymers based on N-(trimethylsilyl)maleimide

N-(Trimethylsilyl)maleimide (TMSMI) has been polymerized with various styrenic monomers (XSt) in the presence of a radical initiator to give high-molecular-weight, alternating copolymers in high yields. The copolymers P(TMSMI/XSt) have high glass transition temperatures above 200°C and thermal decomposition temperatures in the range 320–360°C. The thermal and acidolytic deprotection of trimethylsilyl (TMS) groups of TMSMI units in the copolymers have been investigated. UV irradiation and subsequent heating of a film of P(TMSMI/t-BOCSt) containing a photoacid generator resulted in deprotection of the protecting groups by the photogenerated acids, thereby causing a significant change in solubility of the polymer. Thus positive image patterns were obtained with P(TMSMI/t-BOCSt) by photolithographic processes. © 1998 Society of Chemical Industry