清热利湿健脾温肾法治疗慢性肾炎蛋白尿临床观察

目的:观察清热利湿健脾温肾法治疗慢性肾炎蛋白尿的疗效.方法:82例患者随机分为治疗组50例争对照组32例.治疗组给予具有清热利湿健脾温肾功效的消浊固本汤加味内服,对照组给予复方肾炎片口服.治疗前后分别作尿蛋白定量、血肌苷、尿素氮检测,观察两组临床疗效.结果:消浊固本汤加味组治疗慢性肾炎患者的总有效率为88%,优于复方肾炎片组的总有效率65.62%(P<0.05).结论:清热利湿健脾温肾法能有效治疗慢性肾炎蛋白尿,延缓肾病进程.     

益气养阴清热利湿法治疗慢性肾炎70例

目的:观察运用益气养阴、清热利湿中药组方治疗慢性肾炎的疗效。方法:选择慢性肾炎气阴两虚兼湿热证患者为研究对象,治疗组40例用益气养阴、清热利湿法中药汤剂辨证治疗,对照组30例给予肾炎康复片治疗。结果:治疗组显效率为45%、总有效率为80%;对照组分别为33.3%和63.3%;治疗组优于对照组(P<0.05)。提示:益气养阴、清热利湿法是治疗慢性肾炎气阴两虚兼湿热证的有效治法。     

中西医结合治疗表现为无症状性血尿的非IgA系膜增生性肾炎30例

目的：探讨中西医结合治疗表现为无症状性血尿的非IgA系膜增生性肾炎的疗效。方法：将表现为无症状性血尿的非IgA系膜增生性肾炎患者56例，随机分为2组。中西医结合治疗组30例，对照组26例。中西医结合治疗组采用地塞米松、氮芥结合中药辨证施治；对照组采用雷公藤多苷片口服治疗。结果：中西医结合治疗组总有效率96．67%，对照组总有效率76．92%，两组疗效比较差异有显著性意义（P〈0．01）。结论：中西医结合治疗表现为无症状性血尿的非IgA系膜增生性肾炎具有较好疗效。     

中西医结合治疗系膜增生性肾炎临床观察

目的观察中西医结合治疗系膜增生性肾炎临床疗效。方法将72例本病患者随机分成两组各36例,对照组予以西医常规对症治疗;治疗组在对照组基础上予以活血益气汤治疗。疗程2个月。结果治疗组总有效率为91.66%,对照组为69.44%,治疗组疗效优于对照组(P0.05)。结论中西医结合治疗系膜增生性肾炎疗效较好。     

中西医结合治疗紫癜性肾炎肾病综合征型疗效观察

目的:探讨中西医结合治疗紫癜性肾炎肾病综合征型的临床疗效。方法:采用中西医结合治疗的方法治疗紫癜性肾炎肾病综合征型45例为治疗组,单纯西药治疗20例为对照组,用药24周,观察两组治疗前后临床疗效及尿沉渣红细胞、24h尿蛋白定量、血肌酐的变化。结果:治疗组总有效率91.1%,随访半年无复发。对照组总有效率75.0%。两组间有显著性差异(P<0.05)。提示:中西医结合治疗紫癜性肾炎肾病综合征型较单纯西药治疗疗效显著,复发率低,未发现明显的不良反应。     

小蓟白茅根藕节治疗慢性肾小球肾炎血尿蛋白尿临床研究

[目的]通过运用中药小蓟、白茅根、藕节等治疗慢性肾小球肾炎的临床研究,观察中药治疗慢性肾炎血尿、蛋白尿的疗效。[方法]将已确诊的慢性肾炎患者随机分成对照组、治疗组。两组均予常规西医治疗,治疗组在西医治疗基础上根据中医辨证加减方药,予小蓟、白茅根、藕节等煎服,日1剂水煎分2次服。疗程3个月。[结果]治疗组治疗慢性肾炎总有效率为79.17%,对照组为45.83%。治疗组明显优于对照组(P<0.05)。[结论]中药小蓟、白茅根、藕节等治疗慢性肾小球肾炎血尿、蛋白尿疗效确切;以化瘀止血、清热利湿为主、补肾养阴为辅,能有效减少慢性肾小球肾炎血尿、蛋白尿。     

中西医结合治疗狼疮性肾炎20例疗效观察

目的:观察中西医结合治疗狼疮性肾炎的疗效。方法:选择临床确诊病例41例,随机分为治疗组20例,对照组21例。对照组单纯西药治疗,治疗组在此基础上辨证分4型加服中药。结果:治疗组总有效率95%,对照组总有效率85.7%。2组疗效有显著差异。结论:中西医结合治疗狼疮性肾炎前景广阔。     

益气养阴、清热利湿方治疗慢性肾小球肾炎50例疗效观察

目的:观察益气养阴、清热利湿方治疗慢性肾小球肾炎的临床疗效。方法:将100例慢性肾小球肾炎患者随机分为治疗组与对照组,每组各50例。治疗组予以益气养阴、清热利湿方治疗,对照组予以肾炎康复片治疗。2组治疗周期均为3个月,比较2组综合疗效及尿蛋白、尿红细胞疗效。结果:综合疗效的总有效率治疗组为80. 0%,对照组为56. 0%,组间比较,差异有统计学意义(P 0. 05);尿蛋白疗效的总有效率治疗组为80. 0%,对照组为58. 0%,组间比较,差异有统计学意义(P 0. 05);尿红细胞疗效的总有效率治疗组为74. 0%,对照组为50. 0%,组间比较,差异有统计学意义(P 0. 05)。结论:益气养阴、清热利湿方治疗慢性肾小球肾炎可改善尿蛋白、尿红细胞情况,提高综合疗效,值得临床推广应用。     

中西医结合治疗慢性肾小球肾炎42例观察

目的:观察中西医结合治疗慢性肾小球肾炎的临床疗效。方法:42例随机分为治疗组25例和对照组17例,两组均用西药治疗,治疗组加用中药治疗,治疗6个月。结果:治疗组疾病及症候总有效率均明显优于对照组(P0.05)。结论:中西医结合治疗慢性肾炎疗效显著。     

清化肾炎汤治疗特发性膜性肾病的疗效观察

目的观察清化肾炎汤治疗特发性膜性肾病的疗效。方法将68例特发性膜性肾病患者随机分为治疗组和对照组各34例。对照组予雷公藤多甙片、来氟米特及小剂量泼尼松联合治疗;治疗组加服中药汤剂清化肾炎汤。16周后判断疗效。结果总有效率治疗组为85.29%;对照组为64.70%,两组疗效比较有显著性差异(P0.05)。结论清化肾炎汤联合雷公藤多甙片、来氟米特及小剂量泼尼松治疗特发性膜性肾病疗效满意。     

Analysis of the treatment with traditional Chinese medicine in chronic glomerulonephritis based on histopathologic type]

The histopathologic type of 189 cases of chronic glomerulonephritis (GN) were confirmed by renal biopsies, they were subdivided into 3 groups. 77 patients of Western medicine (WM) group was treated by conventional WM (prednison or CTX), and after treatment the total effective rate was 55.8%. The TCM-WM group was treated by the same WM plus treatment according to Syndrome Differentiation with Chinese medicinal herbs, and the total effective rate was 86% in 50 patients. The TCM group was treated by Chinese medicinal herbs, and the total effective rate was 67.3% in 62 cases. There was very significant difference (P < 0.01) between the WM and the TCM-WM group. Among the patients of TCM-WM and TCM groups, 67% of 112 cases were manifested as Dampness-Heat Syndrome, so it suggested that one of the important method for GN treatment is clearing away Dampness-Heat. The effects of TCM-WM group is much better than the WM group in treating mesangio-proliferative GN and membranous GN. It was difficult for WM in treating IgA nephropathy, membrano-proliferative GN and focal glomerulosclerosis, but Chinese medicinal herbs were effective with replenishing Qi and strengthening the Spleen, clearing away Dampness-Heat, promoting blood circulation and relieving Stasis, etc.     

Treatment of 100 children with infantile nephrotic syndrome by integrated traditional Chinese medicine and Western medicine]

For ten years (1979-1989), 150 cases of infantile nephrotic syndrome were treated by integrated TCM and Western medicine (WM). The WM group (50 cases) was treated by conventional WM drugs (prednisone, CLB, etc) and the TCM-WM group (100 cases) was treated by the above-mentioned WM plus treatment according to Syndrome Differentiation with decoction of Chinese medicinal herbs. Wulin San, Zhenwu Tang and Zhibai Dihuang Tang were selected in treating Spleen-Qi Deficiency distressed by Dampness, both Spleen-Kidney Yang Deficiency and both Liver-Kidney Yin Deficiency Syndrome respectively. The total effective rate was 100%, and the efficacy of TCM-WM group was higher than that of WM group (P < 0.005). The efficacy of TCM-WM treatment of nephritic nephropathy was far better than that of simple nephropathy (P < 0.05). Also the efficacy of TCM-WM was superior in raising plasma albumin and reducing blood cholesterol than that of WM (P < 0.001). The cellular immunity function and plasma cortisol of TCM-WM group were significantly improved than that of WM, P < 0.01 and 0.001 respectively. The result showed that the curative effect of the TCM-WM group in treating nephrotic syndrome was much better than that of WM alone.     

中西医结会治疗成人原发性肾病综合征134例观察

本文探讨了中西医结合治疗成人原发性肾病综合征(PNS)的方法及效果,西医治疗组66例,主要用激素治疗;中西医结合组68例,用中药配合激素治疗。结果表明:用中药配合激素治疗,无论在增加疗效和减少不良反应上,均有相得益彰之效。中西组的有效率达85.3%,而西医组仅56.1%。中西组用激素的不良反应发生率为14.8%,而西医组为48.4%。     

脑热清口服液结合西药治疗颅脑手术后发热的证-效关系研究

目的观察脑热清口服液(简称脑热清)对颅脑手术后发热的退热疗效及中医证型与疗效关系。方法按天坛医院神经外科3个自然病区随机分为3组,对颅脑手术后患者分别用脑热清(脑热清组,86例)、脑热清结合西药(结合组,276例)和西药(西药组,89例)治疗,比较3组退热幅度和退热疗效,结合组中医证型与退热疗效的关系,并观察各种证型治疗前后主要症状的积分变化。结果脑热清组和结合组退热幅度、退热总有效率均明显优于西药组(P<0．01);结合组中医证型的退热疗效从高到低顺序为湿热内蕴型>内热炽盛型>痰热内阻型,且中医证型的主要症状有显著的改善。结论脑热清结合西药对颅脑手术后发热有确切的退热作用,退热效果与中医证型有关,退热的同时能明显改善其临床主要症状。     

Treatment of IgA nephropathy by integrated traditional and Western medicine]

45 cases of IgA nephropathy were confirmed by renal biopsy and were divided into 2 groups, the integrated traditional and western medicine (TCM-WM) therapeutic group and the western medicine (WM) therapeutic group. The WM group was treated by conventional western medicine (persantin, vitamin B co.), and the TCM-WM group was treated by the same western medicine plus differential symptomatic treatment with decoction of Chinese crude herbs. In this paper, most patients (30 cases) were present as deficiency of Yin of the Liver and Kidney type, and were treated by Qiju Dihuang pill plus Erzhi pill. All types in TCM-WM group were also used herbs of promoting blood circulation and remove blood stasis in almost every case. After 6 months of such treatment, the total effective rate of TCM-WM group and the WM group were 86.4% and 13.0% respectively. There was very significant difference (P less than 0.01) between them. The results showed that the curative effect of the TCM-WM group was much superior than WM alone for the treatment of IgA nephropathy.     

中西医结合治疗老年人原发性肾病综合征临床观察

目的：观察中西医结合治疗老年人原发性肾病综合征（ＩＮＳ）的临床疗效。方法：８２例老年人ＩＮＳ患者随机分为治疗组和对照组。治疗组（４１例）有强的松和环磷酰胺（ＣＴＸ）并辨证加服中药，对照组（４１例）单纯用西药治疗。观察临床缓解率、副反应率、副发率及缓解时间。结果：治疗组完全缓解率（５８．５％）和总缓解率（８５．４％）均显著高于对照组（３９．０％、６３．４％，Ｐ〈０．０１）。治疗组副反应率（３６．６％     

中西医结合治疗骨髓增生异常综合征

本文报道50例骨髓增生异常综合征的中西医结合治疗。其中难治性贫血及环形铁粒幼细胞性难治性贫血以调节造血、免疫功能的药物治疗;难治性贫血伴有原始细胞增多、慢性粒单核细胞白血病或转变中的原始细胞增多的难治性贫血给予小剂量化疗,两组均加服中药。两组有效率分别为47.83%及62.96%,总有效率为56%。6例用全反式维甲酸诱导分化治疗,2例有效。11例转为白血病之后用小剂量或联合化疗配合中药治疗,缓解率54.55%,缓解后存活期9～27个月。小剂量化疗具有细胞毒及诱导分化作用。中药可改善症状和体征,利于血像和骨髓像的恢复,防止感染及提高机体免疫力。     

中西医结合治疗输卵管阻塞的临床研究

目的探索一种治疗输卵管阻塞有效而且实用的方法。方法120例输卵管阻塞患者随机采用中西医结合(中西医组)、单纯中药(中药组)、单纯西药(西药组)3种不同方法治疗，观察其疗效；并同时检测血清C反应蛋白(CRP)和白细胞介素-1β(IL-1β)。结果中西医组输卵管双侧通畅率86.7%，妊娠率85.0%；中药组分别为66.7%和63.3%；西药组分别为53.3%和50.0%。3组比较，中西医组效果明显优于中药组和西药组(P＜0.01)。治疗3个疗程后，3组CRP和IL-1β均下降(P＜0.01，P＜0.05)。结论中西医结合治疗输卵管阻塞效果好，实用性强。     

517例肝硬化西医和中西医结合治疗的疗效对比

本文统计了甘肃省12家医院用西医及中西医结合方法治疗肝硬化517例。在降低无腹水组的 SGPT 值、升高有腹水组血清总蛋白和白蛋白、纠正肝性脑病方面,中西医结合治疗组明显优于西医治疗组(P<0.01);有腹水者的治愈好转率达82.7%,亦较西医组的66.1%为高(P<0.01);病死率远低于西医组(P<0.01),提示中西医结合治疗肝硬化的效果较单纯西医治疗优越。     

中西医结合治疗放射性溃疡17例

用中西医结合治疗放射性溃疡１７例并与单纯西药对照观察，治疗组总疗效（９４．１％）明显优于对照组（５２．９％），治疗组平均止痛时间６２．１８天，平均疮面液化时间８０．１６天，平均有效时间１０７．５５天，均较对照组短（Ｐ〈０．０１），提示中西医结合治疗有较好的腐脱、敛疮、止痛作用，可加速放射性溃疡的愈合。外治疗法在本病治疗中具有重要作用。