《中西医结合心血管病电子杂志》稿约

正《中西医结合心血管病电子杂志》由国家新闻出版总署批准、国家食品药品监督管理总局主管、中国医药科技出版社主办的连续型电子出版物,本刊为月刊。国内统一刊号:CN 11-9336/R,国际刊号:ISSN 2095-6681,是国内外公开发行的     

《中西医结合心血管病电子杂志》稿约

正《中西医结合心血管病电子杂志》由国家新闻出版总署批准、国家食品药品监督管理总局主管、中国医药科技出版社主办的连续型电子出版物,本刊为月刊。本刊采用图文声像多种形式,反应我国中西医结合心血管病学领域临床及科研工作新成果、新进展、新经验,介绍学科发展趋势,促进跨学科学术交流,提升我国心血管医学水平。本刊辟有临床研究、理论研究、教学研究、中医文化、文献综述、诊断技术、调查分析、护理研究、病例报告、药物分析、名医撷华、基础研究等众多     

再谈医学科技期刊的质量监控

以相关的国家标准和法规为依据，三年来对有代表性的“中华”、“中国”及部分省市出版的医学期刊计６０余种５００余期进行了系统的刊后审读和研究。认为我国医学科技期刊现状不容乐观，期刊质量有滑坡趋势，应予重视。除认真提高编辑部的整体素质外，刊后审读是监督期刊质量的重要手段。     

学术期刊论文题名的审读及其编辑加工

通过对目前学术期刊论文题名拟、编中存在的各种问题进行分析,对学术期刊论文题名进行审读的要素和编辑加工应遵循的基本原则进行了一些探讨,以引起学术期刊编辑对论文题名审读和编辑加工的重视.     

电子出版物的发展及其对图书馆工作的影响

电子计算机管理图书文献信息，已成为图书情报单位追求的目标，电子出版物进入图书馆也是大势所趋，对电子出版物及其种类、电子出版物的发展历史进行了阐述，并就电子出版物对图书馆工作及其工作人员将产生的影响进行了探讨。     

药学期刊插图质量调查分析

目的:了解药学期刊插图的质量,找出差距,改进编辑工作.方法: 对2006年出版的38种(44期)药学期刊的插图质量进行审读调查.结果: 共审读插图1 609个,存在问题的插图532个,占33.1%;从各期刊看,有问题插图所占百分率最低的为3.7%,其次为4.2%,最高的为80.4%,其次为79.7%;把质量问题分为7类,其中标目词问题最多(17.8%),其次为绘制和印刷质量(9.4%),最少问题的是处理和设计不当(0.6%);地方性期刊和中药方面的期刊问题较多.结论:药学期刊编辑应重视插图的质量问题,加强学习与交流,了解计算机制图方法,重视对作者的培养,才能提高期刊的插图质量.     

开发和利用电子出版物存在的问题及对策

随着现代通信技术及网络技术的迅猛发展,电子出版物在全球迅速发展,强烈地冲击着传统的生产方式和社会结构.在西方一些发达国家,信息产业每年以20%-30%的速度增长,电子出版物已占出版物总发行量1/5左右,美国已有15 000余种杂志拥有电子版,美国国会图书馆准备投资数亿美元,将其整个馆藏8 830多万种资料数字化,以电子出版物形式通过因特网在世界范围内高速传播[1].     

网络电子出版物对高校图书馆服务模式的影响

一、网络电子出版物在图书馆领域的发展学者师曾志给网络电子出版物下了个简单明了的定义:“网络电子出版物的概念从广义上来理解,是将信息以电子方式记录在计算机主机的硬盘介质上并能进行复制,通过计算机网络向公众传播发行的行为。网络电子出版物简单地理解,是以网络为基础的存储、传播和获取信息和知识的产品,它主要包括联机数据库、电子期刊、电子报纸以及电子书等”。[1]网络电子出版物可以简单的理解为在网络上传递的数字化信息资源,它通过网络这一媒介,可以同时向多个用户传递,是一种可以共享的的信息资源,不存在传统图书馆服务中的一人占有其他人就无法使用的现象。网络电子出版物可以在本地站点中通过存储信息资源来建立存储量庞大的数据库,也可以通过建立虚拟链接来获取其他站点的信息资源。网络电子出版物是用户获取信息资源的一种方便有效的途径。与传统的印刷相比,网络电子出版物开拓了新的信息载体,带来了丰富多彩的信息资源,满足了人们对信息获取的多样性、动态性、及时性的需求。目前,网络电子出版物被广泛用于图书馆领域,是现代化的图书馆信息资源不可或缺的重要组成部分。网络电子出版物引进图书馆以后,改变了信息资源传播的方式,由传统的纸质介质转换到纸质与电...     

西文电子图书对图书馆的影响与对策

电子图书是数字化资源建设的重要部分。在信息化、知识化高速发展的今天，电子出版物的应用和普及必将越来越广泛，电子图书在馆藏结构中的比例也越来越大，它与纸质文献一起共同构筑起图书馆的馆藏文献资源体系。图书馆必须紧紧把握这一发展趋势，加强对电子出版物的特点、采访的策略及利用途径的研究。电子图书的引进对图书馆的发展是机遇，更是挑战。     

电子信息的知识产权保护

随着高科技的发展与信息时代的到来,我国信息高速公路和信息网络建设已经全面铺开,电子出版物和多媒体层出不穷,目不暇接.人们以电子方式创造、组织、存储、检索、回溯和传递信息,电子出版物近几年来无论在发达国家,还是在发展中国家都发展很快.据报道,1994年全球电子出版物品种已达11837种,9180万部,近两年增长速度有增无减.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Electro-Acupuncture Combined with the Trigger Point Needle-Embedding for Treatment of Primary Trigeminal Neuralgia in 31 Cases

In recent years, the author of this essay has applied electro-acupuncture combined with the trigger point needle-embedding for treatment of primary trigeminal neuralgia in 31 cases, yielding satis- factory results as reported in the following.     

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Objective： To explore the role of matrix metalloproteinase-1,2 （MMP-1, MMP-2） and tissue inhibitor of matrix metalloproteinases-1 （TIMP-1） in endometriosis. Methods： The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.endometria from 40 subjects （excluding endometriosis） were collected and examined by in situ hybridization technology and western blot assay. Results： Both expressions of MMP-1 and -2 were stronger in ectopic endometrium and eutopic endometrium than in normal endometrium. On the contrary, the expression of TIMP-1 in ectopic endometrium and eutopic endometrium was lower. The differences were significant （P 〈 0.01 ）. Moreover, there was no relationship among the expressions of MMP-1, 2 and TIMP-1 in ectopic endometrium. Conclusion： The expressions of MMP-1, 2 and TIMP-1 lose balance and lack of periodic changes in ectopic endometrium , which explains the biological invasive behavior of endometriosis. It was suggested-that regulating the balance between the MMPs and TIMP-1 should be an ideal therapeutic target to endometriosis.     

Shi Da-zhuo (史大卓) —An outstanding cardiologist of integrative medicine

Prof. SHI Da-zhuo, Ph.D., male, was born on March 20, 1960. Prof. SHI entered the Ph.D. program in 1990 at the China Academy of Chinese Medical Sciences under the supervision of Prof. CHEN Ke-ji, majoring in the treatment of cardiovascular diseases. After receiving his Ph.D. degree in 1993, Prof. SHI started working at the Cardiovascular Center in Xiyuan Hospital affiliated to China Academy of Chinese Medical sciences.     

Persist in and Carry Forward the Integrative Medical Research——Speech at the 6th National General Congress of Chinese Association of Integrative Medicine by Academician CHEN Zhu,Minister of Ministry of Health

The 6th National General Congress of Chinese Association of Integrative Medicine （CALM） was convened at 19-20, April 2008 in Beijing. Academician CHEN Zhu, the minister of Ministry of Health indicated at the congress that the integration of Chinese and Western medicine is very well in keeping with the situation of our country and the general rule of development in medical science; and as a good integration of Chinese medicine and Western medicine, it is mutually beneficial and advantageous to both of them. Seeing the creativity shown in integrative medical investigation in theoretic and methodological sides, we should and must persist in and develop it.