Anderson Hynes肾孟成形术治疗肾盂输尿管连接部梗阻

目的 探讨Ａｎｄｅｒｓｏｎ Ｈｙｎｅｓ肾盂盛形有术对肾盂输尿管连接部梗阻的疗效。方法 采用Ａｎｄｅｒｓｏｎ Ｈｙｎｅｓ肾盂成形术治疗２５例病人的３０个肾盂输尿管连接部梗阻,并随访观察。结果 随访３～３２个月,２５例中２４例（２９个肾脏）术后症状减轻或消失,肾盂、肾盏扩大程度明显减轻,吻合口通畅,无并发症发生。１例因术后吻合口狭窄而行佃尿管肾盏吻合术。结论 Ａｎｄｅｒｓｏｎ Ｈｙｎｅｓ肾盂成形术是治     

肾盂输尿管连接部梗阻的手术治疗

目的;探讨肾盂输尿管连接部梗阻的最佳方案及引流方式。方法：报告６３例（７０例）肾盂输尿管连接部梗阻病人,４８例行Ａｎｄｅｒｓｏｎ－Ｈｙｎｅｓ肾盂成形术,６例行肾盂瓣输尿管成形术,５例行Ｙ－Ｖ成形术,１１例行肾切除术。     

肾盂输尿管连接部梗阻48例术式分析

分析４８例肾盂输尿管连接梗阻手术治疗方式中，行ＦｏｌｅｙＹ－Ｖ成形术１６例，离断性肾盂成形术（Ａｎｄｅｒｓｏｎ－Ｈｙｎｅ手术）１９例，患肾切除术１０例，保守治疗３例，认为Ａｎｄｅｒｓｏｎ－Ｈｙｎｅ术较理想，并对肾切除指征进行讨论。     

离断性肾盂成形术治疗先天性肾盂输尿管连接部梗阻

1994年 1月～ 2 0 0 2年 1月 ,我院共采用离断性肾盂成形术 (Ａｎｄｅｒｓｏｎ Ｈｙｎｅｓ术 )治疗先天性肾盂输尿管连接部梗阻 5 1例 ,疗效满意 ,现报告如下。1　临床资料1 1　一般资料 :本组 5 1例 ,均为单侧病变 ,男 19例 ,女 32例 ,年龄 6～ 4 0岁 ,平均 2 1岁。术前经Ｂ超、ＩＶＵ及逆行肾盂造影检查确诊 ,ＩＶＵ患肾不显影6例 ,重度积水 31例 ,中度积水 14例 ,狭窄段长度0 5～ 3ｃｍ不等。术后病理报告均支持肾盂输尿管连接部梗阻的诊断。1 2　手术方法 :5 1例均采用离断性肾盂成形术 ,术中彻底切除肾盂输尿管连接部的狭窄段 ,包括相…     

离断式肾盂成形术治疗肾盂输尿管连接部梗阻

肾盂输尿管连接部梗阻是泌尿系统常见的梗阻性病变 ,所引起肾积水的手术治疗应早期进行。合理的整形手术 ,可纠正肾盂输尿管连接部异常 ,消除肾积水 ,恢复肾功能[1] 。本院自 1996年 5月至 2 0 0 0年 9月共收治肾盂输尿管连接部梗阻患者 39例 ,均行离断式肾盂成形术 (Ａｎｄｅｒｓｏｎ Ｈｙｎｅｓ术 ) ,取得满意疗效 ,报告如下。1　临床资料1 1　一般资料　肾盂输尿管连接部梗阻患者 39例 ,男 33例 ,女 6例。年龄 8～ 5 4岁 ,平均 2 7 9岁 ,左侧 30例 ,右侧 9例 ,合并肾结石者 15例。因腰痛就诊者 30例 ,因外伤后血尿就诊者 9例。既往手术史…     

先天性肾积水的手术治疗

目的：探讨小儿先天性肾盂输尿管连接部梗阻性肾积水的治疗方法。方法：３０只肾采用ＡｎｄｅｒｓｏｎＨｙｎｅｓ肾盂成形术；对积水严重、皮质菲薄部分采用肾折叠术。结果：ＡｎｄｅｒｓｏｎＨｙｎｅｓ肾盂成形术后，腹痛、血尿等症状消失，肾功能不同程度恢复。结论：掌握手术操作要点，防止术后感染，是手术成功的要点。     

肾盂输尿管连接部狭窄的手术治疗

肾盂输尿管连接部（ＵＰＪ）狭窄是原发性肾积水的常见原因之一。我院自１９８１年１月至１９９９年８月共收治３３例患者，用离断性肾盂成形术（Ａｎｄｅｒｓｏｎ－Ｈｙｎｅｓ术）治疗３０例，３４侧，报告如下：１一般资料 本组３３例，男２４例，女９例。年龄６月～５４岁，平均１６．２岁，双侧病变４例，占１２％。上腹部肿块１７例，疼痛２３例，血尿２例，并发肾结石３例。全部病例均行静脉肾盂造影，１８例患肾未显影，其余均显影延迟，肾盂、肾盏有不同程度的积水，逆行肾盂造影１０例，肾盂穿刺造影２１例，显示肾盂肾盏扩张，Ｕ…     

肾盂输尿管连接部梗阻37例报告

目的:提高对肾盂输尿管连接部梗阻的诊疗效果.方法:总结我院1992～1999年37例肾盂输尿管连接部梗阻的诊疗情况,行离断式肾盂成形23例,非离断式肾盂成形9例,成形术后行肾折叠缝合5例,放置支架肾造瘘管28例,双丁管引流4例,患肾切除5例.结果:32例成形术后无尿瘘及吻合口狭窄,5例并行肾折叠缝合术,随访1.5～3年.肾脏轻至中度积水.结论:肾盂输尿管连接部梗阻患者,一旦确诊应及时治疗,肾盏扩张严重并行肾折叠缝合术,应用双J管内引流.     

儿童肾盂输尿管连接部梗阻术后再手术病因分析

目的 探究儿童肾盂输尿管连接部梗阻（UPJO）术后再手术的原因。方法 回顾我科2015年1月至2017年12月收治的肾盂成形术后因再次梗阻而接受手术的UPJO患儿的临床资料,分析再手术的原因。结果 共有36例患儿接受肾盂成形术后再手术治疗,术中发现梗阻原因为： 26例（72.22%）吻合口水肿增厚、周围粘连与纤维化瘢痕形成,5例（13.89%）吻合口旁或肾盂壁息肉,5例（13.89%）高位输尿管开口,3例（8.33%）迷走血管压迫输尿管,2例（5.56%）吻合口远端输尿管狭窄,2例（5.56%）肾盏颈闭锁。2例患儿因肾盏颈闭锁行肾盏颈成形＋输尿管肾下盏吻合术,其余患儿均接受开放离断式肾盂成形术。术后中位随访时间为28个月,其中34例患儿未发生再梗阻。1例肾盏颈闭锁患儿术后上、下盏间及输尿管肾盏颈吻合口均再次闭锁,再次行肾盏颈成形＋输尿管肾下盏吻合术;另1例患儿再次术后30个月出现患侧腰腹部疼痛伴积水增大,再次行肾盂成形术证实为前次吻合口再次瘢痕性狭窄。上述2例患儿经过第3次手术,术后分别随访37、20个月,无再梗阻发生。结论 吻合口水肿增厚、周围粘连与纤维化瘢痕形成是肾盂成形术后再手术最主要的原因。医源性息肉、输尿管开口位置偏高、首次手术遗漏迷走血管压迫和吻合口远端输尿管狭窄,及吻合时闭合肾盏颈也是导致肾盂成形术后再手术的重要原因。术中应注意选择输尿管较宽敞处精细吻合,保持吻合口位于肾盂低位、避免误伤肾盏颈、避免遗漏存在的迷走血管、造瘘管头端尽量远离吻合口等操作细节有助于减少肾盂成形术后再梗阻的发生。     

后腹腔镜肾盂成形术在肾盂输尿管连接部梗阻中的应用价值

目的 探讨后腹腔镜肾盂成形术治疗肾盂输尿管连接部梗阻（UPJO）的适应证、手术技,于及应用价值。方法采用后腹腔径路对28例确诊为UPJ0的患者行腹腔镜下离断肾盂成形术。结果28例手术均获成功。手术时间110～200min,平均175min;出血量50～100ml,平均75ml。术后住院时间8～20d。围术期无并发症。随访3～19个月,肾盂输尿管连接部（UPJ）吻合口无狭窄,患者肾积水、肾功能均得到改善。结论后腹腔镜治疗肾孟输尿管连接部梗阻创伤小,患者术后痛苦小、恢复快、住院时间短、疗效显著,可以作为肾孟输尿管连接部梗阻治疗的首选方法,值得临床推广应用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Electro-Acupuncture Combined with the Trigger Point Needle-Embedding for Treatment of Primary Trigeminal Neuralgia in 31 Cases

In recent years, the author of this essay has applied electro-acupuncture combined with the trigger point needle-embedding for treatment of primary trigeminal neuralgia in 31 cases, yielding satis- factory results as reported in the following.     

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Objective： To explore the role of matrix metalloproteinase-1,2 （MMP-1, MMP-2） and tissue inhibitor of matrix metalloproteinases-1 （TIMP-1） in endometriosis. Methods： The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.endometria from 40 subjects （excluding endometriosis） were collected and examined by in situ hybridization technology and western blot assay. Results： Both expressions of MMP-1 and -2 were stronger in ectopic endometrium and eutopic endometrium than in normal endometrium. On the contrary, the expression of TIMP-1 in ectopic endometrium and eutopic endometrium was lower. The differences were significant （P 〈 0.01 ）. Moreover, there was no relationship among the expressions of MMP-1, 2 and TIMP-1 in ectopic endometrium. Conclusion： The expressions of MMP-1, 2 and TIMP-1 lose balance and lack of periodic changes in ectopic endometrium , which explains the biological invasive behavior of endometriosis. It was suggested-that regulating the balance between the MMPs and TIMP-1 should be an ideal therapeutic target to endometriosis.     

Shi Da-zhuo (史大卓) —An outstanding cardiologist of integrative medicine

Prof. SHI Da-zhuo, Ph.D., male, was born on March 20, 1960. Prof. SHI entered the Ph.D. program in 1990 at the China Academy of Chinese Medical Sciences under the supervision of Prof. CHEN Ke-ji, majoring in the treatment of cardiovascular diseases. After receiving his Ph.D. degree in 1993, Prof. SHI started working at the Cardiovascular Center in Xiyuan Hospital affiliated to China Academy of Chinese Medical sciences.     

Persist in and Carry Forward the Integrative Medical Research——Speech at the 6th National General Congress of Chinese Association of Integrative Medicine by Academician CHEN Zhu,Minister of Ministry of Health

The 6th National General Congress of Chinese Association of Integrative Medicine （CALM） was convened at 19-20, April 2008 in Beijing. Academician CHEN Zhu, the minister of Ministry of Health indicated at the congress that the integration of Chinese and Western medicine is very well in keeping with the situation of our country and the general rule of development in medical science; and as a good integration of Chinese medicine and Western medicine, it is mutually beneficial and advantageous to both of them. Seeing the creativity shown in integrative medical investigation in theoretic and methodological sides, we should and must persist in and develop it.