腹腔镜胆总管探查取石术62例临床分析

目的探讨腹腔镜胆总管探查取石术的手术方式、适应证。方法回顾性分析2002年2月至2004年8月62例腹腔镜胆总管探查取石术的临床资料。结果62例均在胆道镜的配合下完成腹腔镜胆总管探查取石术。其中胆总管切开取石后置T管引流20例，胆总管切开取石后一期缝合42例。2例发生术后胆漏。结论对腹腔镜下胆总管探查取石术，不管是采取T管引流还是一期缝合，只要掌握手术方式及适应证，腹腔镜下治疗胆总管结石是可行的，是一种创伤小、恢复快、安全可靠的微创手术。     

腹腔镜胆道镜联合一期缝合治疗胆总管结石的临床探讨(附16例报告)

目的:探讨联合应用腹腔镜、胆道镜治疗胆总管结石和一期缝合术的临床经验。方法:搜集2006年3月-2009年3月间我院实施腹腔镜胆总管探查一期缝合术16例,总结其手术时间、住院时间、手术并发症,对手术效果进行分析。结果:手术成功16例(100%),手术时间60~150min,住院时间7~20d,发生胆漏1例(6.2%)经腹腔引流治愈,残余结石1例(6.2%)经术后十二指肠镜取石治愈。14例随访6~48个月,平均18个月,无胆漏、胆管狭窄、胆道出血发生。结论:严格掌握手术适应证,选择合适的病例,腹腔镜下胆总管探查一期缝合安全、有效、可行。     

腹腔镜胆总管切开取石一期缝合胆总管58例分析

目的探讨胆囊结石合并胆总管结石经腹腔镜胆囊切除胆总管切开胆道镜探查取石术后一期缝合胆总管的治疗效果。方法回顾性分析行腹腔镜胆囊切除胆总管切开胆道镜探查取石术后一期缝合胆总管的58例胆囊结石合并胆总管结石患者的临床资料。结果 58均成功施行腹腔镜下胆囊切除+胆总管切开胆道镜取石一期缝合术,手术时间1～3 h,术后发生胆漏32例,漏液均<100 ml/d,30例在3～7 d内停止胆漏,2例16 d后好转。本组31例患者获得随访,随访时间6～12个月,均行磁共振胰胆管造影复查,示胆道通畅,无结石及狭窄。结论腹腔镜下胆总管切开胆道镜取石术后一期缝合胆总管治疗胆囊结石合并胆总管结石具有不带T管、创伤小、恢复快及住院时间短的优点,值得推广。     

腹腔镜联合胆道镜胆总管切开取石术52例临床疗效观察

目的 探讨腹腔镜联合胆道镜胆总管切开探查取石术的疗效.方法 2009年3月至2012年3月云南省安宁市人民医院普外科对52例患者施行腹腔镜胆囊切除、胆总管切开取石术,回顾分析治疗效果.结果 52例患者均顺利完成手术,2例患者中转开腹,中转率为3.85％,手术时间51～158 min,平均为86 min.其中7例胆总管一期缝合,45例放置T管,3例胆漏,发生率为5.77％,经引流治疗后愈合;6例胆管残留结石,发生率为11.54％,术后3月经胆道镜取出.结论 腹腔镜联合胆道镜胆囊切除、胆总管探查取石术治疗胆总管结石具有安全有效、创伤小、住院时间短、恢复快等优点,值得推广.     

腹腔镜联合胆道镜胆总管切开取石术疗效观察

目的探讨腹腔镜联合胆道镜手术治疗胆总管结石的临床价值。方法对42例胆总管结石患者均采用腹腔镜联合胆道镜下胆总管探查取石术进行治疗。结果手术成功率为95.2%(40/42),2例中转开腹;平均手术时间为107 min;术中平均出血60 mL;术后腹腔平均引流量平均85 mL;胃肠道平均恢复时间31 h;平均住院时间6 d;术后有残余结石1例,经T管窦道胆道镜取石术治愈;术后出现胆漏1例;术后随访无胆道残余结石或胆道狭窄等并发症发生。结论腹腔镜联合胆道镜下胆总管探查取石术治疗胆总管结石切实可行。     

腹腔镜联合胆道镜胆总管探查取石术的临床应用体会

目的：探讨腹腔镜联合胆道镜在胆总管探查取石术中的应用价值。方法：除1例胆囊切除术后患者行腹腔镜联合胆道镜胆总管探查取石术,29例患者均行腹腔镜联合胆道镜胆总管探查取石术并切除胆囊。结果：30例手术全部成功,均置T管引流,术后2个月拔管,顺利康复,无出血、腹腔感染等并发症,住院时间9~15 d。1例结石残留,并发胆漏3例。结论：腹腔镜联合胆道镜胆总管探查取石术安全、可行,创伤小,术后恢复快。     

腹腔镜联合胆道镜行胆总管切开取石术18例临床分析

目的 探讨腹腔镜联合胆道镜行胆总管切开取石术的技巧和临床经验及教训.方法 回顾总结2008年1月至2009年10月经腹腔镜联合胆道镜胆总管切开取石术的的临床资料.结果 18例手术均获成功,手术时间100～240 min,出血量50～100 ml,未中转进腹, 18例均行T管引流;术中、术后无胆漏等并发症发生.结论 腹腔镜联合胆道镜胆总管探查取石术具有创伤小、恢复快、住院时间短的优点,治疗胆总管结石安全、有效.     

腹腔镜联合胆道镜治疗胆总管结石临床分析

目的探讨腹腔镜联合胆道镜治疗胆总管结石的临床疗效。方法回顾性分析59例经影像学检查确诊为胆总管结石患者的临床资料及随访结果。经胆囊管胆道镜探查胆总管取石34例;胆总管切开胆道镜探查取石胆总管一期缝合12例;胆总管切开胆道镜探查加T管引流术13例。结果 59例均顺利完成手术,无一例中转开腹。一期缝合术后2例发生短暂胆漏,经3～5d引流后胆漏自行愈合。手术时间65～165min;术中出血40～180ml;住院6～10d,随访1～2年无复发结石。结论腹腔镜联合胆道镜治疗胆总管结石,具有微创手术的优点,安全有效,并发症少,可替代传统的开腹胆总管切开探查T管引流术。     

腹腔镜联合胆道镜胆总管切开取石一期缝合术45例体会

目的:探讨腹腔镜胆总管切开联合胆道镜取石一期缝合术治疗胆囊结石合并胆总管结石的可行性、手术指征及适应证。方法:共45例腹腔镜下胆总管切开联合胆道镜取石后一期缝合术患者临床资料予回顾性分析及总结。结果:手术全部成功。术后出现胆漏2例(4.44%),予充分引流2~6 d愈合。术后随访0.5~2年,复查彩超、MRCP均未见结石残留及胆管狭窄,复查肝功能正常。结论:应用腹腔镜胆总管切开联合胆道镜取石一期缝合术治疗胆囊结石合并胆总管结石是一种安全有效的治疗方法,但应跟严格掌握手术适应证及禁忌证,选择病例合适,熟练掌握操作技巧以提高手术成功率和安全性。     

三镜联合治疗胆道结石的临床应用研究

目的 探讨腹腔镜、纤维胆道镜、十二指肠镜三镜联合治疗胆道结石的临床应用价值.方法 回顾性分析收治的86例胆道结石患者,运用三镜联合的手术方式进行微创治疗.结果 78例患者取石成功,取石成功率90.6%.其中50例行LC+腹腔镜胆总管探查"T"管引流+胆道镜取石术,6例行LC+腹腔镜胆总管探查I期缝合+胆道镜取石术,8例行LC+经胆囊管胆总管探查+胆道镜取石术.18例患者行ERCP+EST+LC,2例患者术后因胆漏再次开腹行"T"管引流,6例术中造影胆总管结石≥1.5 cm无法取出行鼻胆管引流(ENBD)后行开腹手术.76例患者随访约6个月,其中6例患者术后胆总管结石复发,再次行ERCP+EST后治愈.余患者在随访期间,无胆道狭窄及结石残留.结论 三镜联合治疗胆道结石具有安全、有效、微创、并发症少等优点,临床有推广应用价值.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.