共查询到18条相似文献,搜索用时 140 毫秒
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以聚丙烯酰胺(PAM),聚氨酯(PU)为制备凝胶的基本单元,通过在室温下将线性PAM溶解和分散在水中,添加PU组分,制备出一种合成简便的聚丙烯酰胺/聚氨酯(PAM/PU)水凝胶,并研究了其对Pb~(2+)的吸附性能,探索了吸附的最佳组分,结果表明凝胶在15%(wt)PAM,40 g/L PU吸附效果最好,PAM分子量对凝胶的吸附性能影响较小。 相似文献
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聚乙烯醇水凝胶在生物医学工程领域的用途非常广泛。本文就PVA水凝胶的制备、改性及其在生物医学工程中的应用进行综述,简述了PVA水凝胶的溶胀和收缩机理,同时对其发展方向进行了展望。 相似文献
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采用聚乙二醇、Ymer N120、聚丙二醇和异佛尔酮二异氰酸酯为原料,以三乙醇胺作交联剂合成聚氨酯(PU)预聚物,浸入白芨多糖(BSP)和丙烯酰胺(AM)混合溶液,通过自由基聚合制备了负载BSP的PU/PAM双网络水凝胶.采用FTIR、SEM对水凝胶的结构和形貌进行了表征,通过拉力试验机和生物实验对其力学性能和生物性能进行了测试.结果表明,当三乙醇胺用量为多元醇物质的量的60%时,双网络水凝胶具有高溶胀率(256%)的同时保持一定的拉伸强度(1.9 MPa)和高压缩强度(22.7 MPa).双网络水凝胶具有抗菌抗氧化作用,其中,双网络水凝胶对大肠杆菌和金黄色葡萄球菌的抑菌带宽度分别为0.5~4.0和0.5~3.5 mm,羟基自由基清除率最高为28%;溶血率低于5%,细胞存活率最高达101.3%±3.6%,表明双网络水凝胶具有良好的生物相容性. 相似文献
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可注射水凝胶在组织工程中应用进展 总被引:5,自引:1,他引:4
组织工程采用可注射原位形成水凝胶,与预成型支架相比具有特定的优势:能填充任意形状的缺损,并在很大程度上降低植入对机体组织的侵入性,且能与各种治疗药物混合。本文介绍了可注射凝胶形成过程及几种水凝胶系统.并以实例说明可注射水凝胶在组织工程中的应用。 相似文献
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《聚氨酯工业》2019,(5)
粒状4,4'-二氨基二苯甲烷(MDA)与水按质量比为1∶1制得糊状MDA,再以不同比例的聚乙烯吡咯烷酮(PVP)采用包浆法对MDA颗粒表面进行包覆,制备出了4种物理钝化改性的扩链剂。按扩链系数0. 8分别对用聚四氢呋喃二醇(PTMG2000)和2,4-甲苯二异氰酸酯(2,4-TDI)制备的预聚体进行扩链,制备了4种聚氨酯(PU)弹性体,并对扩链反应凝胶时间和PU弹性体的性能进行了研究。结果表明,钝化后的MDA为扩链剂制备的PU弹性体凝胶时间比钝化前的有大幅度延长,在MDA与PVP质量比为20∶(1~2. 5)范围,凝胶时间随PVP用量的增加而延长,25℃时凝胶时间均能延长到60 min以上,改善了制备浇注型PU弹性体的可操作性,解决了扩链剂MDA与PU预聚体相容性差等问题。当MDA与PVP质量比为20∶1. 5时,PU弹性体的力学性能最佳。 相似文献
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Maria Bercea Luiza Madalina Gradinaru Ioana‐Alexandra Plugariu Mihaela Mandru Daniel Laurentiu Tigau 《Polymer International》2020,69(2):149-155
The rheological behaviour of polyurethane (PU) and poly(vinyl alcohol) (PVA) was investigated in aqueous solution and the hydrogel state. The dependence of viscosity on polymer concentration is discussed. The formation of supramolecular structures induced by temperature increase or shear conditions was evidenced. In PU solutions, as temperature increases, a self‐assembling process occurs due to hydrogen bonding and hydrophobic interactions determining a thermoreversible hydrogel formation. In creep and recovery tests, the weak PU network presents high elasticity only at low shear stress (below 10 Pa); it recovers only 15%–20% of strain above 40 Pa and the hydrogel structure fails at high shear stress (above 150 Pa). Also, PU hydrogel is not able to recover its structure after being submitted to successive low and high deformations. In PVA solutions, a shear induced aggregation was observed at 37 °C. PVA hydrogels obtained by the freezing–thawing method present high elasticity and stability due to the strong polymer–polymer interactions established between the polymer chains. Physical networks based on PU/PVA mixtures synergistically combine the characteristics of the two polymers, showing high elasticity when a shear stress up to 3000 Pa is applied during the creep test followed by a fast recovery of the hydrogel structure after exhibiting successive levels of deformation (self‐healing ability). Therefore, these hydrogels are suitable materials for tissue engineering applications. © 2019 Society of Chemical Industry 相似文献
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温度、pH及离子强度敏感性聚氨酯水凝胶的合成与性能研究 总被引:2,自引:0,他引:2
以甲苯二异氰酸酯(TDI)、聚乙二醇(PEG-6000)、二羟甲基丙酸(DMPA)及三乙撑四胺(TEFA)等为原料,合成了温度、pH、及离子强度敏感性聚氨酯水凝胶(PUHG)。研究了PUHG溶胀率(SR)受温度(T)、pH、离子强度(I)、交联剂用量等因素的影响。结果表明PUHG的溶胀率在20~45℃的范围内随温度的升高而减小,45℃后不再变化;在酸性(pH4)溶液中收缩,在碱性(pH9)溶液中溶胀,表现出良好的pH值敏感性;在一定温度和pH下,随着离子强度的增加PUHG的溶胀率减小。水凝胶溶胀动力学研究表明,PUHG具有良好的溶胀-退胀可逆性。 相似文献
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Hydrogels are attractive materials for constructing underwater antifouling coatings on solid substrates. However, the application of hydrogel coatings usually faces the obstacles of complex preparation process and poor durability. Herein, we present a facile method to prepare durable hydrogel coatings on metal foils based on rationally designed supramolecular polyurea (PU) hydrogels. PU hydrogels are designed to be cross-linked with hydrogen bonds (H-bonds) and hydrophobic interactions in the hard segment domains by using dihydrazides with different alkyl spacer lengths ( (CH2)m ) as chain extender. The synergy of H-bond and hydrophobic interaction can stabilize H-bonds in water, as confirmed by Raman spectroscopy. As a result, PU hydrogels exhibit antiswelling capacity and robustness in both deionized water and seawater. Subsequently, PU hydrogel coatings on Cu/Al foils are prepared by convenient brush coating and subsequent swelling. The resulting hydrogel coatings exhibit excellent underwater anti-oil-adhesion and self-cleaning property, and are durable enough to withstand various static and dynamic damaging tests. The good durability of PU hydrogel coatings should be ascribed to the robust adhesion interface and excellent antiswelling capacity of PU hydrogels. The combination of facile preparation and good durability makes PU hydrogel coatings promising candidates for reliable underwater antifouling. 相似文献
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Bioinspired Tunable Sacrificial Bonds Endowing Tetra‐PEG Based PU Hydrogel with Tunable Mechanical Properties,Shape‐Memory,and Self‐Healing Functions
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Development of hydrogels with excellent and tunable mechanical properties combining with multifunctions is an intriguing issue in material science and engineering. Herein, bioinspired tunable sacrificial bonds are introduced into the tetra‐poly(ethylene glycol) (PEG) based polyurethane (PU) (TP) network to afford a hydrogel with tunable mechanical properties, shape‐memory, and self‐healing functions. The mussel‐inspired compound of Lysine‐dopamine (LDA) is introduced into the network of TP hydrogel through polyurethane/polyurea chemistry to form LDA‐tetra‐PEG‐PU (LTP) hydrogel. As catechol groups in LDAs can intermolecularly interact with each other and can also coordinate with ferric ions with different coordination ratios, these physical interactions with different strengths in the afforded LTP hydrogel construct kinds of sequentially tuned sacrificial bonds. As a result, these sacrificial bonds preferentially rupture prior to the covalent network upon external loading, which dissipate the energy and endow the hydrogel with advanced and postadjustable mechanical properties. This mechanism is investigated in detail. Furthermore, the LTP hydrogel shows multifunctions such as shape‐memory and self‐healing abilities. In addition, the tetra‐PEG based hydrogel shows remarkable thermoresponsiveness that the hydrogel distinctly contracts with the increase of the temperature. The improved mechanical strength and multifunctions should enlarge the application areas of the tetra‐PEG based hydrogel in various fields. 相似文献
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Blood compatibility and physicochemical assessment of novel nanocomposite comprising polyurethane and dietary carotino oil for cardiac tissue engineering applications
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Saravana Kumar Jaganathan Mohan Prasath Mani Manikandan Ayyar Navaneetha Pandiyaraj Krishnasamy Gomathi Nageswaran 《应用聚合物科学杂志》2018,135(3)
Cardiovascular diseases (CVD) were estimated to claim 17 million lives each year. Among these, coronary heart disease almost accounts 50% deaths associated with CVD, which causes the blockage of the coronary arteries that supplies blood to the heart. Nowadays, the cardiac tissue engineering have become a promising solution to overcome the drawbacks associated with current therapies. Further, the scaffold used in cardiac tissue engineering must possess thromboresistant and anticoagulant nature to serve as a plausible candidate for cardiovascular applications. In this present investigation, a novel nanocomposite based on polyurethane (PU) and carotino oil was fabricated using electrospinning. Scanning electron microscopy images indicated that the nanocomposites have smaller fiber diameter (702 ± 130 nm) compared to the pristine PU (969 ± 217 nm). The Fourier transform infrared spectroscopy analysis confirmed the interaction between the carotino oil and PU by the formation of hydrogen bond and shifting of CH peak. The contact angle of electrospun PU/carotino oil was found to be 119°, which was increased compared to pristine PU (86°) indicating the hydrophobic nature of developed nanocomposites. Moreover, the surface roughness and thermal stability were found to be enhanced due to the presence of carotino oil in the PU matrix indicated in atomic force microscopy and thermogravimetric analysis. The enhanced surface roughness of nanocomposites resulted in delayed activation of the blood clot as revealed in activated partial thromboplastin time and prothrombin time assay. Moreover, the hemolytic index of fabricated nanocomposites was found to very low of about 1.33% compared to pristine PU (2.73%), suggesting non‐hemolytic nature and also better blood compatibility. So, the developed PU/carotino nanocomposites having desirable characteristics like better physicochemical and blood compatibility may render appropriate potentials for raw materials of cardiac tissue engineering. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135, 45691. 相似文献