| 自动计划与人工计划在宫颈癌术后VMAT放疗中的剂量学比较 |
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| 引用本文： | 吴建篪,邓婷,赵罂.自动计划与人工计划在宫颈癌术后VMAT放疗中的剂量学比较[J].中国医学物理学杂志,2020,37(8):989-992. |
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| 作者姓名： | 吴建篪 邓婷 赵罂 |
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| 作者单位： | 1.郴州市第一人民医院妇科， 湖南 郴州 423000； 2.广西柳州市妇幼保健院门诊， 广西 柳州 545001 |
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| 摘 要： | 目的:观察并比较自动计划与人工计划在宫颈癌术后患者容积弧形调强（VMAT）中的剂量学参数，对自动计划应用于临床宫颈癌术后放疗中的可行性进行研究。方法:选取2018年11月~2019年11月郴州市第一人民医院接受放射治疗的宫颈癌患者30例，将其作为对象展开临床分析与探究。采用Pinnacle放射治疗计划系统，分别进行VMAT人工计划与自动计划，比较两种计划靶区的D95、Dmean、均匀性指数（HI）、适形度指数（CI）、危及器官的剂量参数。结果:人工计划与自动计划在D95的比较差异无统计意义（P>0.05）；人工计划与自动计划在靶区Dmean、HI、CI的比较差异显著（P<0.05）。人工计划与自动计划在膀胱、骨、小肠、直肠、右侧股骨头及左侧股骨头的危及器官剂量体积比较，差异有显著意义（P<0.05）。结论:VMAT自动计划与VMAT人工计划比较，自动计划的计划质量较高，可提高剂量参数合理性，应用Pinnacle放射治疗计划系统自动计划的宫颈癌术后VMAT计划，临床可行性较高，可将VMAT自动计划应用于临床宫颈癌术后放疗中。
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| 关 键 词： | 宫颈癌 自动计划 人工计划 容积弧形调强 放射剂量 |
Dosimetric comparison between automatic planning and manual planning in volumetric modulated arc therapy of cervical cancer |
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| WU Jianchi,DENG Ting,ZHAO Ying.Dosimetric comparison between automatic planning and manual planning in volumetric modulated arc therapy of cervical cancer[J].Chinese Journal of Medical Physics,2020,37(8):989-992. |
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| Authors: | WU Jianchi DENG Ting ZHAO Ying |
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| Affiliation: | 1. Department of Gynaecology, Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China 2. Outpatient Department, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou 545001, China |
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| Abstract: | Abstract: Objective To observe and compare the dose parameters between automatic planning and manual planning in volumetric modulated arc therapy (VMAT) for patients with cervical cancer after surgery, and to study the feasibility of automatic planning in postoperative radiotherapy of cervical cancer. Methods Thirty patients with cervical cancer who received radiotherapy in Chenzhou No.1 Peoples Hospital from November 2018 to November 2019 were enrolled for clinical analysis and exploration. Pinnacle treatment planning system was used for manual and automatic VMAT planning. The D95, Dmean, homogeneity index, conformity index of target areas and the dose parameters of organs-at-risk were compared between two plans. Results There were significant differences in the Dmean, homogeneity index and conformity index of target areas between manual planning and automatic planning (P<0.05), but not in D95 (P>0.05). Moreover, there were statistical differences in the dose-volume parameters of bladder, bone, small intestine, rectum, right femoral head and left femoral head between manual planning and automatic planning (P<0.05). Conclusion Compared with manual VMAT planning, automatic VMAT planning has higher planning quality and can improve the rationality of dose distribution. The VMAT plan automatically planned by Pinnacle treatment planning system which has higher clinical feasibility can be applied to the postoperative radiotherapy of cervical cancer. |
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| Keywords: | Keywords: cervical cancer automatic planning manual planning volumetric modulated arc therapy radiation dose |
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