| 112例新型冠状病毒肺炎患者肝肾功能和心肌酶学变化分析 |
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| 引用本文： | 王联发,陈晨,王艳,唐郡,张骏飞,黄猛珣,刘波. 112例新型冠状病毒肺炎患者肝肾功能和心肌酶学变化分析[J]. 实用肝脏病杂志, 2021, 24(3): 351-354. DOI: 10.3969/j.issn.1672-5069.2021.03.012 |
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| 作者姓名： | 王联发 陈晨 王艳 唐郡 张骏飞 黄猛珣 刘波 |
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| 作者单位： | 230031 合肥市 解放军联勤保障部队第901医院心内二科(陈晨,王联发,王艳,黄猛珣); 消化内科(唐郡); 感染病科(刘波); 安徽医科大学第一附属医院感染病科(张骏飞) |
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| 摘 要： | 目的 观察新型冠状病毒肺炎(COVID-19)患者血清肝肾功能和心肌酶学的变化.方法 在本组112例COVID-19肺炎患者中,普通型68例,重型22例,危重型22例.常规检测血清肝肾功能指标及肌钙蛋白T(cTnT)、肌红蛋白(Myo)和肌酸激酶同工酶(CK-MB).结果 各组COVID-19肺炎患者血清肾功能指标变化...
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| 关 键 词： | 新型冠状病毒肺炎 肝肾功能 心肌酶学 预后 |
| 收稿时间： | 2021-01-08 |
Serum liver and kidney function tests and myocardial enzymes in 112 patients with coronavirus-19 pneumonia |
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| Chen Chen,Wang Lianfa,Wang Yan,et al. Serum liver and kidney function tests and myocardial enzymes in 112 patients with coronavirus-19 pneumonia[J]. Journal of Clinical Hepatology, 2021, 24(3): 351-354. DOI: 10.3969/j.issn.1672-5069.2021.03.012 |
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| Authors: | Chen Chen Wang Lianfa Wang Yan et al |
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| Affiliation: | Department of Cardiology, 901st Hospital, Hefei 230031,Anhui Province, China |
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| Abstract: | Objective The aim of this study was to analyze the changes of serum liver and kidney function tests and cardiac muscle enzymes in patients with coronavirus-19(covid-19)pneumonia.Methods The clinical materials in 112 patients with covid-19 pneumonia were retrospectively analyzed and it included typical type in 68,severe type in 22 and critical type in 22.Serum liver and kidney function tests and myocardial enzyme cardiac troponin Test(cTnT),myohemoglobin(Myo)and creatine kinase Isoenzyme-MB(CK-MB)levels were determined routinely.Results There was no significant difference as respect to serum renal function tests in the three groups(P>0.05);the abnormal incidences of serum ALT and AST in critical patients were 31.8%and 45.5%,much higher than 4.6%and 13.6%(P<0.05)in severe ones or 0.0%and 2.9%(P<0.05)in patients with typical ones;the abnormal elevated incidences of serum cTnT,Myo and CK-MB in critical patients were 72.7%,45.5%and 27.3%,significantly higher than 22.7%,16.6%and 9.1%,respectively(P<0.05)in severe patients or 4.4%,1.5%and 1.5%,respectively(P<0.05)in typical patients;out of 24 patients with abnormal serum myocardial enzyme,the fatality rate was 25%,much higher than 1.1%(P<0.05)in 88 patients with normal serum myocardial enzyme.Conclusion The results from a single-centered retrospective study suggest that the patients with covid-19 pneumonia could have serum myocardial enzyme elevation,which might hint the critical clinical type and poor prognosis. |
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| Keywords: | Coronavirus-19 pneumonia Liver and kidney function tests Myocardial enzymes Prognosis |
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