| 50岁及以上中老年HIV/AIDS患者心理健康与服药依从性的关系研究 |
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| 引用本文： | 谭卓1,余彬2,' target='_blank'>1,余军3,熊君3,何坤明4,周会彬5,贾鹏6,王菊7,吉克春农7,杨淑娟1. 50岁及以上中老年HIV/AIDS患者心理健康与服药依从性的关系研究[J]. 现代预防医学, 2023, 0(11): 2082-2087. DOI: 10.20043/j.cnki.MPM.202211063 |
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| 作者姓名： | 谭卓1 余彬2 ' target='_blank'>1 余军3 熊君3 何坤明4 周会彬5 贾鹏6 王菊7 吉克春农7 杨淑娟1 |
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| 作者单位： | 1.四川大学华西公共卫生学院/华西第四医院，四川 成都610041；2.四川大学灾后重建与管理学院；3.泸县疾病预防控制中心；4.金堂县疾病预防控制中心； 5.简阳市疾病预防控制中心； 6.武汉大学资源与环境科学学院；7.凉山州疾病预防控制中心 |
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| 摘 要： | 目的 探索四川省中老年HIV/AIDS患者抑郁症状、焦虑症状和抗逆转录病毒治疗服药依从性的关系，为改善该人群服药依从性提供科学依据。方法 在四川省的艾滋病高发县区，对符合纳入标准的对象进行调查，采用抑郁症筛查量表（PHQ-9）和广泛性焦虑障碍量表（GAD-7）测量心理健康，自我报告法判断服药依从性，单因素分析，多因素二元logistic回归分析抑郁、焦虑症状和服药依从性的关系，亚组分析探索不同人群间是否存在差异。结果 共1 288人完成了调查，抑郁症状总分的均分为（4.43±4.90）分，焦虑症状总分的均分为（2.75±4.24）分，调查对象中依从的占85.56%，不依从的占14.44%。多因素分析显示，抑郁症状与服药依从性呈负相关，且症状越明显关联强度越大(轻度：OR=0.58,95%CI:0.38～0.89；中度：OR=0.51,95%CI:0.28～0.94；重度：OR=0.42,95%CI:0.18～0.95)。轻度焦虑与依从性正相关(OR=1.71,95%CI:1.01～2.93)。亚组分析显示，抑郁、焦虑症状对服药依从性的影响在不同户口性质的人群间存在差异。结论 中老年HI...
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| 关 键 词： | 艾滋病病毒感染者/艾滋病患者 中老年 抑郁 焦虑 服药依从性 |
Study on the relationship between mental health and medication compliance in middle-aged and elderly patients with HIV/AIDS aged 50 and over |
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| TAN Zhuo,YU Bin,YU Jun,XIONG Jun,HE Kun-ming,ZHOU Hui-bin,JIA Peng,WANG Ju,JIKE Chun-nong,YANG Shu-juan. Study on the relationship between mental health and medication compliance in middle-aged and elderly patients with HIV/AIDS aged 50 and over[J]. Modern Preventive Medicine, 2023, 0(11): 2082-2087. DOI: 10.20043/j.cnki.MPM.202211063 |
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| Authors: | TAN Zhuo YU Bin YU Jun XIONG Jun HE Kun-ming ZHOU Hui-bin JIA Peng WANG Ju JIKE Chun-nong YANG Shu-juan |
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| Affiliation: | *West China School of Public Health/West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China |
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| Abstract: | Objective To explore the relationship between depressive symptoms, anxiety symptoms, and drug compliance of antiretroviral therapy (ART) in middle-aged and elderly patients with HIV/AIDS in Sichuan Province, so as to provide scientific basis for improving medication compliance. Methods The subjects who met the inclusion criteria were investigated in the counties with high incidence of AIDS in Sichuan Province. Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder Scale -7(GAD-7) were used to measure mental health. Medication compliance was judged according to self-report results. Univariate analysis and multivariate logistic regression analysis were used to analyze the relationship between depression, anxiety symptoms, and medication compliance. Results A total of 1 288 people completed the survey. The average total scores of depressive symptoms and anxiety symptoms were (4.43±4.90) and (2.75±4.24), respectively, and the compliance with ART was 85.56%. Multivariate analysis showed that depressive symptoms were negatively correlated with medication compliance, and the more obvious the symptoms, the greater the correlation strength (mild: OR=0.58, 95%CI: 0.38-0.89; moderate: OR=0.51, 95%CI: 0.28-0.94; severe: OR=0.42, 95%CI: 0.18-0.95). Mild anxiety was positively correlated with compliance (OR=1.71, 95%CI: 1.01-2.93). Subgroup analysis showed that the effects of depression and anxiety symptoms on medication compliance varied among people with different household registry. Conclusion The mental health of middle-aged and elderly patients with HIV/AIDS is an important factor affecting their compliance with ART. Different degrees of depression and anxiety symptoms and different populations have varying effects on compliance. Different groups should be provided with corresponding psychological support to improve their medication compliance and health status. |
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| Keywords: | HIV/AIDS patients Middle-aged and elderly Depression Anxiety Medication compliance |
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