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双源计算机断层摄影对先天性心脏病的诊断
引用本文:王怡宁,孔令燕,苗齐,方理刚,李烁,周慷,王志伟,徐凯,樊红苓,金征宇. 双源计算机断层摄影对先天性心脏病的诊断[J]. 协和医学杂志, 2011, 2(3): 200-204. DOI: 10.3969/j.issn.1674-9081.2011.03.002
作者姓名:王怡宁  孔令燕  苗齐  方理刚  李烁  周慷  王志伟  徐凯  樊红苓  金征宇
作者单位:1.中国医学科学院 北京协和医学院 北京协和医院 放射科, 北京 100730
摘    要:  目的  探讨双源计算机断层摄影(dual-source computed tomography, DSCT)诊断先天性心脏病(先心病)的临床应用价值。  方法  DSCT增强扫描检查先心病患者20例, 年龄4个月~53岁, 平均19岁; 所有病例均以心脏超声(echocardiography, ECHO)为对照, 并经手术证实。  结果  20例患者经手术证实的心内外结构畸形共63处, DSCT检出59处, 诊断敏感性为93.7%;ECHO检出55处, 诊断敏感性87.3%, 两种方法诊断敏感性比较差异无统计学意义(χ2=1.474, P=0.225)。63处结构畸形中, 心脏部分畸形41处, DSCT检出37处(90.2%), ECHO检出37处(90.2%), 两者敏感性相当(P=1.000);心脏-大血管连接处畸形9处, DSCT检出9处(100%), ECHO检出8处(88.9%), 差异无统计学意义(P > 0.05);大血管部分畸形13处, DSCT检出13处(100%), ECHO检出10处(76.9%), 差异无统计学意义(P > 0.05)。  结论  DSCT能够显示心内外结构畸形, 具有较高的诊断敏感性, 对先天性心脏病, 特别是合并心外大血管畸形的诊断有重要价值。

关 键 词:心脏缺损,先天性   断层摄影术,X线计算机   超声心动描记术
收稿时间:2011-05-18

Dual-source Computed Tomography for the Diagnosis of Patients with Congenital Heart Disease
WANG Yi-ning,KONG Ling-yan,MIAO Qi,FANG Li-gang,LI Shuo,ZHOU Kang,WANG Zhi-wei,XU Kai,FAN Hong-ling,JIN Zheng-yu. Dual-source Computed Tomography for the Diagnosis of Patients with Congenital Heart Disease[J]. Medical Journal of Peking Union Medical College Hospit, 2011, 2(3): 200-204. DOI: 10.3969/j.issn.1674-9081.2011.03.002
Authors:WANG Yi-ning  KONG Ling-yan  MIAO Qi  FANG Li-gang  LI Shuo  ZHOU Kang  WANG Zhi-wei  XU Kai  FAN Hong-ling  JIN Zheng-yu
Affiliation:1.Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China2.Department of Cardiac Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China3.Department of Cardiolory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Abstract:Objective To evaluate the value of dual-source computed tomography (DSCT) in the diagnosis of congenital heart disease. Methods Twenty patients aged 4 months to 53 years (mean age 19 years) with congenital heart disease underwent contrast-enhanced DSCT. The results were compared with those of echocardiography (ECHO) and confirmed by surgery. Results Among the 20 patients, DSCT detected 59 of 63 (93.7%) anomalies that confirmed by surgery, and ECHO detected 55 of 63 (87.3%) (χ2=1.474, P=0.225). In the 41 intracardiac anomalies, DSCT was as sensitive as ECHO (both 90.2%, P=1.000). In the 9 heart-vessel conjunction deformities, no significant difference was found between the sensitivities of two modalities (100% vs. 88.9%, P〉0.05). In the 13 great vessel deformities, no significant difference was found between the sensitivities of two modalities (100% vs. 76.9%, P〉0.05). Conclusion DSCT detects intraand extra-cardiac anomalies with high sensitivity and has an important value in the diagnosis of congenital heart disease especially those with extra-cardiac anomoalies.
Keywords:heart defects  congenital  tomography  X-ray computed  echocardiography  
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