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生物电阻抗法与体重指数在杜氏肌营养不良患儿营养评估中的比较研究
引用本文:赵晓鹏,谢颖,胡环宇,赵丽华,陈银红,李增宁. 生物电阻抗法与体重指数在杜氏肌营养不良患儿营养评估中的比较研究[J]. 中国儿童保健杂志, 2020, 28(8): 917-920. DOI: 10.11852/zgetbjzz2019-1513
作者姓名:赵晓鹏  谢颖  胡环宇  赵丽华  陈银红  李增宁
作者单位:河北医科大学第一医院临床营养科, 河北 石家庄 050031
基金项目:2018年度省医学适用技术跟踪项目(G2018021)
摘    要:目的应用生物电阻抗分析(BIA)检测杜氏肌营养不良(DMD)患儿体成分,并比较体重指数(BMI)与体脂百分比(PBF)判定患儿超重的一致性。方法收集2015年8月-2017年2月在河北医科大学第三医院神经肌肉病科就诊的39例男性DMD患者作为患儿组,同期随机选取46例健康男童作为对照组。应用BIA对两组儿童进行人体成分检测。结果两组儿童的脂肪含量、BMI差异均无统计学意义(P>0.05)。患儿组的身高、体重、身体水分、蛋白质、无机盐、肌肉质量和基础代谢率(BMR)均低于对照组(P<0.05),但患儿组的PBF高于对照组(P<0.05)。患儿组中PBF与年龄呈正相关关系(r=0.546,P<0.05),BMI与PBF在判定DMD患儿超重时的一致性较差(Kappa=0.352,P<0.05)。结论相比于同年龄段同性别的健康少儿,DMD患儿的整体营养状况较差,应用BIA比使用BMI能更加准确地评估患儿的营养状况。

关 键 词:杜氏肌营养不良  生物电阻抗分析  体脂百分比
收稿时间:2019-12-11
修稿时间:2020-02-12

Comparative study on bioelectrical impedance analysis and body mass indexin nutrition assessment of children with duchenne muscular dystrophy
ZHAO Xiao-peng,XIE Ying,HU Huan-yu,ZHAO Li-hua,CHEN Yin-hong,LI Zeng-ning. Comparative study on bioelectrical impedance analysis and body mass indexin nutrition assessment of children with duchenne muscular dystrophy[J]. Chinese Journal of Child Health Care, 2020, 28(8): 917-920. DOI: 10.11852/zgetbjzz2019-1513
Authors:ZHAO Xiao-peng  XIE Ying  HU Huan-yu  ZHAO Li-hua  CHEN Yin-hong  LI Zeng-ning
Affiliation:Department of Clinical Nutrition, the First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China Corresponding author:LI Zeng-ning, E-mail:lizengning@126.com
Abstract:Objective To analyze the body composition of children with duchenne muscular dystrophy (DMD) by bioelectrical impedance analysis (BIA), and to compare the consistency of body mass index (BMI) with the percentage of body fat (PBF) when assessing the overweight of DMD children. Methods A total of 39 male DMD children were enrolled in case group from August 2015 to February 2017 in Neuromuscular Department of the Third Hospital of Hebei Medical University, and 46 healthy boys were randomly selected as control group during the same period.BIA was used to test body composition in two groups. Results There was no significant difference on fat content and BMI between the two groups (P>0.05).The height, weight, body water, protein, inorganic salt, muscle mass and basal metabolic rate (BMR) of DMD children were significantly lower than those in control group (P<0.05).However, the PBF of DMD children was higher than that of the control group (P<0.05).There was positive correlation between PBF and age in DMD children (r=0.546, P<0.05).BMI was poorly consistent with PBF in determining the overweight of children with DMD (Kappa=0.352, P<0.05). Conclusions Compared with healthy children with the same age and gender, the nutritional status of DMD children is poor.BIA can more accurately assess the nutritional status of patients than using BMI.
Keywords:duchenne muscular dystrophy   bioelectrical impedance analysis   percentage of body fat  
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