| 早期预测子痫前期的生物标志物研究进展 |
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| 引用本文： | 叶太阳,林其德,李卫平. 早期预测子痫前期的生物标志物研究进展[J]. 上海交通大学学报(医学版), 2009, 29(6) |
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| 作者姓名： | 叶太阳 林其德 李卫平 |
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| 作者单位： | 上海交通大学医学院仁济医院妇产科,上海200127 |
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| 摘 要： | 子痫前期严重危害母胎健康，寻找有效的早期预测子痫前期的生物标志物意义重大。已相继发现可溶性Fh-1、胎盘生长因子（PIGF）等胎盘来源的生物标志物，并显示出一定的应用前景。同时，蛋白质组学、代谢组学、微小RNA等新技术的发展也为筛选子痫前期早期预测的生物标志物带来了新的希望。
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| 关 键 词： | 子痫前期 预测 生物标志物 |
Research advances in biomarkers for early prediction of preeclampsia |
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| YE Tai-yang reviewer LIN Qi-de,LI Wei-ping reviser. Research advances in biomarkers for early prediction of preeclampsia[J]. Journal of Shanghai Jiaotong University:Medical Science, 2009, 29(6) |
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| Authors: | YE Tai-yang reviewer LIN Qi-de LI Wei-ping reviser |
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| Affiliation: | Department of Obstetrics and Gynecology;Renji Hospital;School of Medicine;Shanghai Jiaotong University;Shanghai 200127;China |
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| Abstract: | Preeclampsia is a leading cause of maternal and infant morbidity and mortality.It is very important to explore the biomarkers for the early prediction of preeclampsia.Some peptides released from placenta,such as soluble Flt-1 and placenta growth factor(PIGF),have been revealed for definite prospects of application.Meanwhile,the recent advances in proteomics,metabolomics and microRNA shed light on searching of new biomarkers for preeclampsia prediction. |
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| Keywords: | preeclampsia prediction biomarker |
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