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三维斑点追踪技术及压力-应变环定量评估妊娠期高血压患者心肌功能的临床价值
引用本文:张萌,宋昇达,杜丽娟,兰亭玉,段凤霞,张惠琴,何文. 三维斑点追踪技术及压力-应变环定量评估妊娠期高血压患者心肌功能的临床价值[J]. 临床超声医学杂志, 2024, 26(1)
作者姓名:张萌  宋昇达  杜丽娟  兰亭玉  段凤霞  张惠琴  何文
作者单位:首都医科大学附属北京天坛医院超声科,清华大学第一附属医院超声科,首都医科大学附属北京天坛医院超声科,首都医科大学附属北京天坛医院超声科,首都医科大学附属北京天坛医院超声科,首都医科大学附属北京天坛医院超声科,首都医科大学附属北京天坛医院超声科
摘    要:目的 探讨实时三维斑点追踪(3D-STI)技术及压力-应变环(PSL)定量评估妊娠期高血压(HDCP)患者左室心肌功能的临床价值。方法 选取我院确诊的HDCP患者33例(HDCP组)和同期正常妊娠孕妇32例(对照组),收集两组一般资料,应用常规超声心动图及多普勒获得舒张末期左室内径(LVDd)、左室后壁厚度(LVPWTd)、室间隔厚度(IVSTd),以及二尖瓣口舒张早期及舒张晚期血流速度峰值(E、A)、二尖瓣环舒张早期运动速度峰值(E’)及Tei指数;应用3D-STI获得左室整体纵向应变(GLS)、整体径向应变(GRS)、整体圆周应变(GCS)、整体面积应变(GAS)、左室舒张末期容积指数(EDVI)、左室收缩末期容积指数(ESVI)、每搏量(SV)、射血分数(EF)、心输出量(CO);应用PSL获得左室整体做功效率(GWE)、左室整体有用功(GCW)、左室整体无用功(GWW)、左室整体做功指数(GWI),比较两组上述指标的差异。结果 ①临床资料:HDCP组体表面积、收缩压、舒张压均较对照组增高,差异均有统计学意义(均P<0.05)。②常规超声心动图参数:HDCP组IVSTd、LVPWTd均较对照组增厚,E’较对照组减低,Tei指数较对照组增高,差异均有统计学意义(均P<0.05)。③3D-STI参数: HDCP组GLS、GCS、GRS、GAS均较对照组减低,EDVI、ESVII、SV、CO较对照组增高,差异均有统计学意义(均P<0.05);两组EF比较差异无统计学意义。④PSL参数:HDCP组与对照组GWE、GCW、GWW、GWI比较差异均无统计学意义。结论 HDCP患者左室心肌功能较正常妊娠孕妇减低,但排除后负荷影响后,HDCP患者左室心肌做功并无明显改变;应用3D-STI技术及PSL可准确评估HDCP患者心肌功能是否受损,可为临床诊治提供参考依据。

关 键 词:超声心动描记术  斑点追踪,三维  压力-应变环  妊娠期高血压  心肌功能
收稿时间:2023-07-08
修稿时间:2023-11-24

The Clinical Value of Three-dimensional Speckle Tracking Imaging and Pressure-strain Loop in Quantitative Evaluation of Left Ventricular Function in Patients with Hypertensive Disorder Complicating Pregnancy
zhangmeng,songshengd,dulijuan,lantingyu,duanfgengxi,zhanghuiqin and hewen. The Clinical Value of Three-dimensional Speckle Tracking Imaging and Pressure-strain Loop in Quantitative Evaluation of Left Ventricular Function in Patients with Hypertensive Disorder Complicating Pregnancy[J]. Journal of Ultrasound in Clinical Medicine, 2024, 26(1)
Authors:zhangmeng  songshengd  dulijuan  lantingyu  duanfgengxi  zhanghuiqin  hewen
Affiliation:Beijing Tian Tan Hospital, Capital Medical University,,,,,,
Abstract:Objective To investigate the clinical value of three-dimensional speckle tracking imaging(3D-STI)and pressure-strain loop(PSL) in quantitative evaluation of left ventricular myocardial function in patients with hypertensive disorder complicating pregnancy(HDCP).Methods Thirty-three patients with HDCP (HDCP group) and 32 normal pregnant women (control group) were selected. The general data of the two groups were collected. Left ventricular end-diastolic diameter(LVDd),left ventricular posterior wall thickness(LVPWTd),ventricular septal thickness(IVSTd),mitral flow velocity(E,A),mitral ring motion velocity(E '') and Tei index were obtained by conventional echocardiography and Doppler technology. Global longitudinal strain(GLS),global area strain(GAS),global lateral strain(GRS),global circumferential strain(GCS),left ventricular end-diastolic volume index(EDVI),left ventricular end-systolic volume index(ESVI),stroke volume index(SVI),ejection fraction(EF),cardiac output(CO) were obtained by 3D-STI.PSL was used to obtain left ventricular global work efficiency(GWE),global active work(GCW),global idle work(GWW),global work index(GWI),and the statistical differences of the above indexes between two groups were compared. Results ①Clinical data: the body surface area,systolic blood pressure and diastolic blood pressure in HDCP group were significantly higher than those in control group (all P < 0.05). ②Conventional echocardiographic parameters: IVSTd and LVPWTd in HDCP group were thicker than those in control group, E ''was lower than that in control group and Tei index was higher than that in control group,the differences were statistically significant (all P < 0.05). ③3D-STI parameters:GLS,GAS,GRS and GCS in HDCP group were lower than those in control group(all P < 0.05).There was no significant difference in EF between the two groups. ④PSL parameters:there was no significant difference in GWE,GCW,GWW and GWI between HDCP group and control group. Conclusion The left ventricular myocardial function of HDCP patients is reduced compared with normal pregnancy,but the left ventricular myocardial work of HDCP patients has no significant change after excluding the influence of afterload.3D-STI and PSL can accurately assess whether the myocardial function of HDCP patients is impaired,and provide help for clinical diagnose and treatment.
Keywords:Echocardiography   Speckle tracking  Three Dimension  Pressure-strain Loop  hypertensive disorder complicating pregnancy  Myocardial function
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