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Xpert MTB/RIF在结核性胸膜炎诊断中的研究进展
引用本文:曾 路1,2,王 曼1,刘 侠2,王水利3. Xpert MTB/RIF在结核性胸膜炎诊断中的研究进展[J]. 现代检验医学杂志, 2019, 0(6): 161-165
作者姓名:曾 路1  2  王 曼1  刘 侠2  王水利3
作者单位:(1.西安医学院,西安710068;2. 陕西省结核病防治院, 西安710100;3. 陕西省人民医院 呼吸与危重症一病区,西安710068)
摘    要:结核性胸膜炎是引起胸腔积液常见的原因之一,其诊断主要通过临床表现、影像学、实验室检查等综合判断。结核性胸膜炎诊断常用检测技术包括胸腔积液细胞生化检查、结核分枝杆菌抗体检测、结核分枝杆菌涂片及培养等,但敏感度及特异度不高。结核分枝杆菌/ 利福平耐药实时荧光定量核酸扩增检测技术(Xpert MTB/RIF)为诊断结核病新兴技术手段,在肺结核病诊断方面有较高应用价值,但在结核性胸膜炎诊断方面临床研究报道较少,部分观点不统一,该文对其在诊断结核性胸膜炎的研究进展进行综述。

关 键 词:结核分枝杆菌/ 利福平耐药实时荧光定量核酸扩增检测技术(Xpert MTB/RIF)  结核性胸膜炎

Research Progress of Xpert MTB/RIF in Diagnosis of Tuberculous Pleurisy
ZENG Lu1,' target="_blank" rel="external">2,WANG Man1,LIU Xia2,WANG Shui-li3. Research Progress of Xpert MTB/RIF in Diagnosis of Tuberculous Pleurisy[J]. Journal of Modern Laboratory Medicine, 2019, 0(6): 161-165
Authors:ZENG Lu1,' target="  _blank"   rel="  external"  >2,WANG Man1,LIU Xia2,WANG Shui-li3
Affiliation:(1.Xi’an Medical University,Xi’an 710068,China;2. Tuberculosis Hospital of Shaanxi Province,Xi’an 710100,China;3. Respiratory and Critical Illness Ward 1, Shaanxi Provincial People’s Hospital,Xi’an 710068,China)
Abstract:Tuberculous pleurisy was one of the common reasons which causing pleural effusion. It was diagnosed mainly bythe comprehensive judgment of clinical presentation,imaging features,laboratory examination,and so on. The technologieswhich were usually used in the diagnosis of tuberculous pleurisy included cytobiochemical examination of pleural effusion,detection of Mycobacterium tuberculosis antibody, smear and culture of Mycobacterium tuberculosis, etc, but the sensitivity andspecificity remained low. Xpert MTB/RIF was one of the new technology to diagnose tuberculosis,which had high value indiagnosing lung tuberculosis. In diagnosing tuberculous pleurisy, there were few clinical studies and some views hadn’t reach anagreement. This paper was to review the research progress of Xpert MTB/RIF in tuberculous pleurisy diagnosis.
Keywords:
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