| 颅内动脉瘤夹闭术后应激性溃疡的危险因素及其对病人预后的影响 |
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| 引用本文： | 姜维民,曾群,江辉,陈健彤,赵雪,郭凌志,杨佳宁. 颅内动脉瘤夹闭术后应激性溃疡的危险因素及其对病人预后的影响[J]. 中国临床神经外科杂志, 2018, 0(8): 532-534. DOI: doi:10.13798/j.issn.1009-153X.2018.08.007 |
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| 作者姓名： | 姜维民 曾群 江辉 陈健彤 赵雪 郭凌志 杨佳宁 |
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| 作者单位： | 作者单位:411000 湖南，湘潭市中心医院神经外科（姜维民、曾 群、江 辉、陈健彤、赵 雪、郭凌志、杨佳宁） |
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| 摘 要： | 目的 探讨颅内动脉瘤夹闭术后发生应激性溃疡（SU）的危险因素及其对病人预后的影响。方法 回顾性分析2016年1月1日至2017年12月31日夹闭术治疗的69例颅内动脉瘤的病例资料。采用多因素Logistic回归分析SU发生的危险因素。结果 69例中，术后发生SU 16例（23.19%，SU组），未发生SU 53例（无SU组）。多因素Logistic回归分析显示术前高Hunt-Hess分级是颅内动脉瘤夹闭术后并发SU的独立危险因素（OR=11.81；95% CI 1.42~98.35；P=0.022）。69例中，痊愈38例，好转21例，自动出院6例，在院死亡4例（5.8%）。SU组ICU住院时间[（13.44±9.49）d]明显长于无SU组[（8.75±5.55）d；P=0.016]。但是SU组总住院时间[（28.19±10.18）d]和治疗有效率（81.25%，13/16）与无SU组[分别为（26.13±9.60）d、（86.79%，46/53）]均无统计学差异（P>0.05）。结论 SU是颅内动脉瘤夹闭术后常见并发症，术前高Hunt-Hess分级是SU的独立危险因素，且SU可明显增加ICU住院时间。
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| 关 键 词： | 颅内动脉瘤 夹闭术 应激性溃疡 危险因素 预后 |
Risk factors related to stress ulcer after clipping of intracranial aneurysms and its effects on prognosis |
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| JIANG Wei-min,ZENG Qun,JIANG Hui,CHEN Jian-tong,ZHAO Xue,GUO Ling-zhi,YANG Jia-ning.. Risk factors related to stress ulcer after clipping of intracranial aneurysms and its effects on prognosis[J]. Chinese Journal of Clinical Neurosurgery, 2018, 0(8): 532-534. DOI: doi:10.13798/j.issn.1009-153X.2018.08.007 |
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| Authors: | JIANG Wei-min ZENG Qun JIANG Hui CHEN Jian-tong ZHAO Xue GUO Ling-zhi YANG Jia-ning. |
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| Affiliation: | Department of Neurosurgery, Xiangtan Central Hospital, Xiangtan 411000, China |
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| Abstract: | Methods The clinical data of 69 patients with intracranial aneurysms undergoing clipping from January, 2016 to December, 2017 were analyzed respectively. The risk factors related to the stress ulcer were analyzed statistically. Results Of 69 patients, 16 suffered from the stress ulcer and 53 not after the clipping of intracranial aneurysms. The univariate analysis showed that there were significant differences in the operation duration and the Hunt-Hess grade between the two groups (P<0.05) and the multivariate analysis showed that the high Hunt-Hess grade is an independent risk factor of the stress ulcers in the patients with intracranial aneurysms after the clipping. In addition, ICU stay was significantly longer in the patients with stress ulcers than those in the patient without stress ulcers (P<0.05). Conclusions The stress ulcer occurs often after the clipping in the patients with intracranial aneurysms and significantly extent the patients’ ICU stay. High Hunt-Hess grade is an independent risk factor of the stress ulcers after the clipping in the patients with intracranial aneurysms. |
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| Keywords: | Intracranial aneurysms Clipping Stress ulcer Risk factors Prognosis |
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