Effect of<Emphasis Type="Italic">Vitex negundo</Emphasis> leaf extract on the free radicals scavengers in complete Freund's adjuvant induced arthritic rats |
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| Authors: | P Renuka Devi S Krishna Kumari C Kokilavani |
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| Affiliation: | (1) Department of Biochemistry, Kovai Kalaimagal College of Arts and Science, Narasipuram, 641 109 Coimpatore, TamilNadu, India;(2) Department of Biochemistry, Kongunadu Arts and Science College, G N Mills Post, 641 029 Coimbatore, TamilNadu, India |
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| Abstract: | The effect of the oral administration ofVitex negundo leaf extract on the levels of enzymic and non-enzymic antioxidants were studied in the adjuvant induced arthritic (AIA) rats
The levels of antioxidant enzymes such as SOD, CAT, GPx, G6PD, GSH and Vit-C were estimated in various groups of the experimental
rats. It was observed that the antioxidant enzyme levels in the AIA were significantly low when compared to normal rats. A
significant decrease in enzymic antioxidant—SOD, CAT, GPx, G6PD and non-enzymic antioxidant—GSH, Vit-C were observed in the
liver of AIA rats compared to the normal rats. These results suggest that the leaf extract ofVitex negundo possesses antioxidant activity. |
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| Keywords: | Antioxidant Free radicals Vitex negundo |
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