磁敏感加权成像对丘脑底核的显示价值

目的评价磁敏感加权成像(SWI)对脑丘底核(STN)的显示价值。方法收集帕金森氏病患者13例,所有患者均接受3.0TMRI检查,扫描序列包括T2W/FSE(T2-weightedfastspin-echo,T2加权快速自旋回波)序列、T2W/FSTIR(T2加权快速短时反转恢复)及SWI序列,分别测量不同序列STN与周围组织(脑白质)的对比度和对比噪声比,并进行比较。结果三组序列STN与脑白质的对比度及对比噪声比存在显著差异。结论 SWI提高了STN与脑白质的对比度及对比噪声比,提高了对STN的显示能力,最大限度地实现了对STN的可视化,对帕金森氏病患者脑深部刺激术(DPS)前定位评价、术中位置准确性的判断具有良好的应用前景。

Display of subthalamic nucleus by susceptibility-weighted imaging

Objective To evaluate the values of subthalamic nucleus （STN） was achieved by using susceptibility-weighted imaging （SWI）. Methods 13 patients with Parkinson＇ s disease, scanned with 3. 0T, scanning sequences included TE-wcighted fast spin-echo （TEW/FSE）, T2- weighted fast short inversion time inversion-recovery （T2W/FSTIR） and susceptibility-weighted imaging （SWI）. The contrast ratio and contrast noise ratio of STN with the surrounding tissue （ white matter） was measured in different sequence and statistically analyzed. Results Using SPSS13.0 statistics software, there is significant difference in three groups sequences about contrast ratio and contrast noise ratio of STN with white matter. Conclusion Contrast ratio and contrast noise ratio of STN with white matter are improved by using SWI , and visibility of STN is improved, the visualization of STN was maximumly achieved, SWI is provided with good application prospect about positioning evaluation before operation and intraoperative position accuracy judgment in deep brain stimulation （DBS） of Parkinson＇ s disease.