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结核性脑膜炎脑脊液细胞学的特征性表现
引用本文:徐仿成,王兴中,陈先文.结核性脑膜炎脑脊液细胞学的特征性表现[J].脑与神经疾病杂志,2009,17(1).
作者姓名:徐仿成  王兴中  陈先文
作者单位:安徽医科大学第一附属医院神经内科,合肥,230022
摘    要:目的探讨脑脊液细胞学检查对结核性脑膜炎早期临床诊断的价值。方法采用玻片离心沉淀法制片收集脑脊液细胞,瑞-姬姆萨染色(MGG),光学显微镜分类计数。结果37例临床诊断为结核性脑膜炎患者的脑脊液细胞学呈以下改变:细胞学形态以斑片状聚集分布的激活型单核细胞、单核吞细胞和巨噬细胞,周围伴中性粒细胞和淋巴细胞,中性粒细胞比例为35.57±22.95%,类似于无反应性肉芽肿样改变。结论形似无反应性肉芽肿样的脑脊液细胞学改变以及中性粒细胞特征性的比率,可能是结核性脑膜炎早期诊断的特征性改变。

关 键 词:结核性脑膜炎  脑脊液细胞学  无反应性肉芽肿  中性粒细胞

The specific manifestation on cerebrospinal fluid cytology of tuberculous meningitis
XU Fang-cheng,WANG Xing-zhong,CHEN Xian-wen.The specific manifestation on cerebrospinal fluid cytology of tuberculous meningitis[J].Journal of Brain and Nervous Diseases,2009,17(1).
Authors:XU Fang-cheng  WANG Xing-zhong  CHEN Xian-wen
Affiliation:XU Fang-cheng,WANG Xing-zhong,CHEN Xian-wen. Department of Neurology,The First Affiliatted Hospital of Anhui Medical University,Hefei 230022,China.
Abstract:Objective To observe the value of cerebrospinal fluid cytological examination on clinical diagnosis of tuberculous meningitis in earlier period. Methods Cells in cerebrospinal fluid were collected by centrifugation on the glass slide,Wright-Giemsa's stained,and calculated the percentage of them by light microscope.Results The specific manifestation on cerebrospinal fluid cytology of 37 cases of tuberculous meningitis by clinical diagnosis were as follow:The morphous were similar to the changes of nonreactiv...
Keywords:tuberculous meningitis  cerebrospinal fluid cytology  nonreactive granuloma  granulocytes  
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