催乳素垂体腺瘤经蝶显微外科治疗

目的 探讨催乳素垂体腺瘤经蝶显微手术的治疗效果。方法 总结１１９例催乳素垂体腺瘤采取经蝶显微手术的治疗安全性与远期疗效。本组女１０７例，男１２例。年龄１３～５６（平均３６．７）岁。术前均经ＣＴ扫描中ＭＲＩ确诊，其中大腺瘤１５例（１２．６１％），微腺瘤１０４例（８７．４％）。手术采取经唇下－鼻中隔－蝶窦入路行肿瘤切除术。结果 术后并发症少，无死亡。１０３例（８６．６％）行随访观察，随访期６月～７．５

Transsphenoidal microsurgical treatment for prolactin-secreting pituitary adenoma

Objective To probe the curative effect on prolactin secreting pituitary adenoma (PRL SPA). Methods The long term efficacy and safety of transsphenoidal microsurgical resection for 119 patients with PRL SPA were reviewed at our department of neurosurgery. There were 107 females and 12 males. The patients ranged in age from 13 to 56 years with a mean of 36.7 years. Preoperative diagnosis was made by CT or MRI scan. Of the patients, 15 (12.6%) were macroadenomas and 104 (87.4%) were microadenomas. Operations were performed via either the sublabio septo sphenoidal approach or the naso vestibulo sphenoidal approach. Results Operative morbidity was low and there was no operative mortality in this group. Long term follow up review ranging from 6 months to 7.5 years (mean 3.5 years) in 103 (86.6%) patients revealed a cure of 88 patients (85.4%). Conclusion The microsurgical technique via transsphenoidal approach to remove PRL SPA is a safe and effective method.