18氟-脱氧葡萄糖心肌代谢显像对心电图呈坏死型患儿的临床价值

目的 探讨18氟-脱氧葡萄糖(18F-FDG)心肌代谢显像对心电图呈坏死型患儿的临床价值。方法对5例心电图呈坏死型患儿应用SPECT／PET进行心肌灌注(99Tc-MIBI法)和18F-FDG心肌代谢显像检查。结果 例1~3(川崎病并冠状动脉瘤、心肌梗死)18F-FDG心肌代谢显像示大部分心肌存活。例4、5(扩张型心肌病。心电图示心肌坏死型)18F-FDG心肌代谢显像示浅淡缺损区,除极小部分放射充填外均未见放射性充填(非存活心肌-坏死或瘢痕形成)。结论 18F-FDG心肌代谢显像检测对判断心肌梗死后存活心肌及扩张型心肌病诊断、治疗和预后判断有重要参考价值。

Clinical significance of 18F-fluorode oxyglucose myocardial metabolic imaging in evaluation of myocardial necrosis demonstrated by electrocardiogram

Objective To investigate the clinical significance of 18F-fluorode oxyglucose(18F-FDG) myocardial metabolic imaging in the evaluation of myocardial necrosis demonstrated by electrocardiogram (ECG). Methods 99Tc-MIBI myocardial perfusion and 18F-FDG myocardial metabolic imaging were used in 5 cases with SPECT/PET. Results 18F-FDG myocardial metabolic imaging showed that most areas of myocardium were demonstrated survivable in 1-3 cases diagnosed as Kawasaki disease with coronary artery aneurysm, myocardial infarction. Case 4 and 5 suffering from dilated cardiomyopathy and myocardial necrosis in ECG showed non-alive myocardium-necrosis in most myocardial areas demonstrated by 18F-FDG myocardial metabolic imaging. Conclusion 18F -FDG myocardial metabolic imaging is of important value in evaluation live myocardium after myocardial infarction and the diagnosis, treatment and prognosis of dilated cardiomyopathy.