| 隐睾症中激素和雌雄激素受体的研究 |
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| 引用本文： | 傅冷西,李笃妙,张建星,林俊山.隐睾症中激素和雌雄激素受体的研究[J].中华小儿外科杂志,2005,26(4):186-188. |
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| 作者姓名： | 傅冷西 李笃妙 张建星 林俊山 |
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| 作者单位： | 1. 350005,福州,福建医科大学附属第一医院中心实验室
2. 350005,福州,福建医科大学附属第一医院小儿外科 |
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| 基金项目： | 福建省科技计划资助项目(编号K20056) |
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| 摘 要： | 目的 从激素和雌雄激素受体变化探讨隐睾症发病机制。方法 化学发光免疫技术检测30例隐睾症和16例斜疝(对照组)患儿血清促卵泡生成激素(FSH)、促黄体生成激素(LH)和睾丸酮(T)激素水平;免疫组化技术观察隐睾症患儿睾丸引带、阴囊肉膜、阴囊皮肤和斜疝患儿疝囊组织雄激素受体(AR)和雌激素受体(ER)表达情况。结果 ①激素水平:隐睾症组血清LH和T水平与斜疝组二者之间无显著性差异(P<0.05);双侧隐睾组血清FSH水平高于斜疝组(0.01
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| 关 键 词： | 雄激素受体 隐睾症 促卵泡生成激素 促黄体生成激素 化学发光免疫 睾丸引带 免疫组化技术 睾丸下降不全 激素水平 阴囊肉膜 阴囊皮肤 雌激素受体 显著性差异 发病机制 技术检测 表达情况 血清LH 双侧隐睾 FSH 低表达 高表达 |
Androgen and estrogen receptor expressions in cryptorchidism |
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| FU Leng-xi,LI Du-miao,ZHANG Jian-xing,LIN Jun-shan.Androgen and estrogen receptor expressions in cryptorchidism[J].Chinese Journal of Pediatric Surgery,2005,26(4):186-188. |
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| Authors: | FU Leng-xi LI Du-miao ZHANG Jian-xing LIN Jun-shan |
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| Abstract: | Objective To assess the expressions of androgen receptor (AR)and estrogen receptor (ER) in cryptorchidism.Methods Serum levels of FSH, LH and Testosterone were studied by fluoresent immunocytometry in 30 patients with cryptorchidism and 16 patients with indirect inguinal hernia (Control group). Expressions of AR and ER in gubernacular ligament, scrotal dartos, scrotal skin and tissue of hernia sac were examined with immunohistochemistry.Results There was no difference in LH and T levels between cryptorchidism and the control groups(P< 0.05). The serum FSH level of patients with bilateral cryptorchidism was significantly higher than that of the control group ( 0.01
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| Keywords: | Cryptorchidism Hormone Receptor androgen Receptor estrogen |
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