| 脑电生物反馈对支气管哮喘患儿的血清皮质醇和神经生长因子的影响及意义 |
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| 引用本文： | 张海燕,刘贺临,刘义红,高琼,王艳华,潘红英.脑电生物反馈对支气管哮喘患儿的血清皮质醇和神经生长因子的影响及意义[J].临床儿科杂志,2011,29(10). |
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| 作者姓名： | 张海燕 刘贺临 刘义红 高琼 王艳华 潘红英 |
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| 作者单位： | 华中科技大学同济医学院附属孝感市中心医院儿科,湖北孝感,432000 |
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| 摘 要： | 目的探讨支气管哮喘的神经心理发病机制,为支气管哮喘的防治提供有利的干预措施。方法将诊断为支气管哮喘的患儿220例随机分为常规GINA方案吸入治疗1组(116例)和常规GINA方案吸入治疗加脑电生物反馈治疗2组(104例),同时选择保健门诊同性别,同年龄,家族中无精神病、癫疒间及智力低下儿童80例为对照组。三组儿童(哮喘患儿一经诊断明确后在未治疗前)均检测血清皮质醇(8 am和4 pm)、神经生长因子(NGF)、脑电波θ/β比值;哮喘患儿经过6个月的治疗后再次复查对上述指标。结果哮喘患儿与对照组儿童的脑电波θ/β比值在治疗前比较差异有统计学意义,经过6个月的治疗后治疗2组θ/β比值接近正常对照组儿童。哮喘患儿在治疗前,8 am和4 pm皮质醇数值均较对照组儿童低,差别有统计学意义,治疗1组治疗前后变化差异无统计学意义,治疗2组6个月后皮质醇8 am测定值较未治疗前明显上升,下午则无明显变化;哮喘组患儿治疗前的NGF数值明显较对照组儿童高,差异有统计学意义,治疗1组治疗后NGF有所下降但差异无统计学意义,治疗2组NGF数值较对照组明显降低,差异有统计学意义。结论适度的神经心理调节可协调下丘脑-垂体-肾上腺轴反应,...
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| 关 键 词： | 哮喘 皮质醇 神经生长因子 脑电生物反馈 儿童 |
Effect of electric biofeedback on serum cortisol and nerve growth factor in children with bronchial asthma and its significance |
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| ZHANG Hai-yan,LIU He-lin,LIU Yi-hong,GAO Qiong,WANG Yan-hua,PAN Hong-ying.Effect of electric biofeedback on serum cortisol and nerve growth factor in children with bronchial asthma and its significance[J].The Journal of Clinical Pediatrics,2011,29(10). |
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| Authors: | ZHANG Hai-yan LIU He-lin LIU Yi-hong GAO Qiong WANG Yan-hua PAN Hong-ying |
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| Affiliation: | ZHANG Hai-yan,LIU He-lin,LIU Yi-hong,GAO Qiong,WANG Yan-hua,PAN Hong-ying(Department of Pediatrics,Central Hospital of Xiaogan Affiliated to Huazhong University of Science and Technology Tongji Medical College,Xiaogan 432000,Hubei,China) |
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| Abstract: | Objective To explore the neuropsychological pathogenesis of bronchial asthma in order to improve the prevention and treatment of bronchial asthma.Methods Two hundred and twenty pediatric patients diagnosed with bronchial asthma were randomly divided into the therapy group one(116 patients)and the therapy group two(104 patients).All asthmatic patients received routine inhalation treatment according to the GINA program.In addition,therapy group two received additional electric biofeedback therapy.Eighty healt... |
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| Keywords: | asthma cortisol nerve growth tactor electric biofeed-back child |
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