MRI在小儿线粒体脑肌病中的诊断价值

目的　探讨MRI在小儿线粒体脑肌病中的诊断价值。方法　搜集自 1996 -0 1～ 2 0 0 0 -12经MRI检查、病理及实验室检查证实的小儿线粒体脑肌病 16例进行回顾性分析。结果　 16例患者脑内病灶均表现为多发对称性略长T1、长T2 信号 ,其中单纯脑深部灰质受累 9例 ,大脑皮质和深部灰质同时受累 4例 ,灰、白质同时受累 2例 ,单纯白质受累 1例。结论　多样化的临床和MRI表现是小儿线粒体脑肌病的特点 ;MRI对小儿线粒体脑肌病的诊断有较大帮助。

Diagnostic Value of MRI in the Mitochondrial Encephalomyopathy in Children

Objective To study diagnostic value of MRI in the mitochondrial encephalomyopathy about children.Methods 16 patients of mitochondrial encephalomyopathy in children had been examinatd with MR,proved by patholigy and biochemical laboratory examinations from 1996 to 2000.All of informations were retrospectively analysed.Results Brain parenchymal lesions in all cases were low signal intensity on T 1-weighted and high signal imtensity on T 2-weighted images.16 patients with mitochondrial encephalomyopathe of children,9 patients of them had only the deep gray matter involved,4 patients had both the deep gray matter and the cerebral cortex involved simultsneously,2 patients had with involvement of cortex and subcortical white matter,1 patient had exclusitvely involvement of white matter.Conclusion The varied clinical and MRI findings are the characteristic of mitochondrial encephalomyopathy,MRI has better helping to the diagnosis of mitochondrial encephalomyopathy in children.