| 辐射致癌病因概率计算方法研究进展 |
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| 引用本文： | 宁静,袁勇,谢向东,杨国山.辐射致癌病因概率计算方法研究进展[J].军事医学科学院院刊,2009,33(6):570-573. |
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| 作者姓名： | 宁静 袁勇 谢向东 杨国山 |
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| 作者单位： | 军事医学科学院放射与辐射医学研究所,北京,100850 |
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| 摘 要： | 为解决辐射致癌患者的赔偿问题,美国国立卫生研究院提出用病因概率（probability of causation,PC）来评估癌症和所受电离辐射之间的关联程度,我国也发布了根据PC判断放射性肿瘤的相关国家标准。本文总结了与PC计算相关的辐射致癌超额危险模型的研究进展,并介绍了超额危险在不同人群之间的转换方法、与低剂量和低剂量率的依赖关系、其他流行病学危险因子的修正方法以及PC的应用情况。
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| 关 键 词： | 肿瘤 辐射性 病因概率 超额危险 危险因素 |
Research advances in probability of causation calculation of radiogenic neoplasms |
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| NING Jing,YUAN Yong,XIE Xiang-Dong,YANG Guo-Shan.Research advances in probability of causation calculation of radiogenic neoplasms[J].Bulletin of the Academy of Military Medical Sciences,2009,33(6):570-573. |
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| Authors: | NING Jing YUAN Yong XIE Xiang-Dong YANG Guo-Shan |
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| Affiliation: | (Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China) |
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| Abstract: | Probability of causation (PC) was used to facilitate the adjudication of compensation claims for cancers diagnosed following exposure to ionizing radiation. In this article, the excess cancer risk assessment models used for PC calculation are reviewed. Cancer risk transfer models between different populations, dependence of cancer risk on dose and dose rate, modification by epidemiological risk factors and application of PC are also discussed in brief. |
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| Keywords: | neoplasms radiation-induced probability of causation excess risk risk factors |
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