| 帕金森病的神经心理学测验和SPECT对照研究 |
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| 引用本文： | 黄延焱,陆怡,贺凤凤.帕金森病的神经心理学测验和SPECT对照研究[J].中国医学计算机成像杂志,2000,6(2):131-134. |
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| 作者姓名： | 黄延焱 陆怡 贺凤凤 |
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| 作者单位： | 黄延焱（上海医科大学附属华山医院200040）;陆怡（上海医科大学附属华山医院200040）;贺凤凤（上海医科大学附属华山医院200040）;赵晋华（上海医科大学附属华山医院200040）;徐一峰（上海精神卫生中心）;宋立升（上海精神卫生中心） |
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| 摘 要： | 研究神经心理学测验和脑ＳＰＥＣＴ对帕金森病（ＰＤ）的诊断价值。材料和方法：对３０例正常老人（ＮＡ）和３１例ＰＤ进行神经心理学测验（ＭＭＳＥ，ＦＯＭ，ＤＳＴ，ＲＶＲ，ＢＤ）和ＳＰＥＣＴ检查，比较两组认知功能和脑血流灌注特点。结果：两组间各测验（ＭＭＳＥ，ＦＯＭ，ＤＳＴ，ＲＶＲ，ＢＤ０结果均有显著差异，ＮＡ各测验是分均高于ＰＤ。与ＮＡ相比，ＰＤ双侧项叶、颞叶、基底节、丘脑的放射性计数比值显著降低（Ｐ〈
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| 关 键 词： | 帕金森病 SPECT 神经心理学测验 |
Comparison of
Neuropsychological Tests andSPECT with 99m Tc - HMPAO in Parkinson' s Disease |
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| Huang Yanyan.Comparison of
Neuropsychological Tests andSPECT with 99m Tc - HMPAO in Parkinson'''' s Disease[J].Chinese Computed Medical Imaging,2000,6(2):131-134. |
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| Authors: | Huang Yanyan |
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| Abstract: | Purpose:To explore the characteristics and diagnotic values of neuropsychological tests and SPECT with 99mTc-HMPAO in Parkinson's disease (PD).Materials and Methods:Five neuropsychological tests and SPECT were performed in 30 normal adults(NA) and 31 PD to observe their cognitive functions and cerebral perfusion.Results:cognitive functions assessed by neuropsychological tests(MMSE,FOM,DST,RVR,BD)and cerebral perfusion examined by SPECT in PD group were significant different from that in NA.The ratioes of all cognitive functions tested were significantly lower in PD group Compared with that in NA group.The cerebral perfusion of PD was significantly decreased in bilateral frontal,parietal,thalamus cortex and basal ganglia in PD compared with those of NA.Relationship and regression analysis showed that there was certain relation between neuropsychological tests and cerebral perfusion.The perfusion in frontal,left parietal and left thalamus cortex was significantly correlated with FOM results(P<0.05),indicating that FOM could reflex indirectly the perfusion in these areas.Conclusion:Neuropsychological tests and brain SPECT can be used as auxiliary means in the diagnosis of PD. |
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| Keywords: | Parkinson's disease SPECT Neuropsychological tests |
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